Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Philip J M, Johnson"'
Autor:
Quentin Bertrand, Przemyslaw Nogly, Eriko Nango, Demet Kekilli, Georgii Khusainov, Antonia Furrer, Daniel James, Florian Dworkowski, Petr Skopintsev, Sandra Mous, Isabelle Martiel, Per Börjesson, Giorgia Ortolani, Chia-Ying Huang, Michal Kepa, Dmitry Ozerov, Steffen Brünle, Valerie Panneels, Tomoyuki Tanaka, Rie Tanaka, Kensuke Tono, Shigeki Owada, Philip J. M. Johnson, Karol Nass, Gregor Knopp, Claudio Cirelli, Christopher Milne, Gebhard Schertler, So Iwata, Richard Neutze, Tobias Weinert, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Time-resolved serial crystallography at X-ray Free Electron Lasers offers the opportunity to observe ultrafast photochemical reactions at the atomic level. The technique has yielded exciting molecular insights into various biological process
Externí odkaz:
https://doaj.org/article/3c025d7fb07142aba6ad9ce725228605
Autor:
Wojciech Błachucki, Philip J. M. Johnson, Ivan Usov, Edwin Divall, Claudio Cirelli, Gregor Knopp, Pavle Juranić, Luc Patthey, Jakub Szlachetko, Henrik Lemke, Christopher Milne, Christopher Arrell
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 2, Pp 233-242 (2024)
To fully exploit ultra-short X-ray pulse durations routinely available at X-ray free-electron lasers to follow out-of-equilibrium dynamics, inherent arrival time fluctuations of the X-ray pulse with an external perturbing laser pulse need to be measu
Externí odkaz:
https://doaj.org/article/72348668dc404a1d816e610e3916cebb
Autor:
Maximilian Wranik, Michal W. Kepa, Emma V. Beale, Daniel James, Quentin Bertrand, Tobias Weinert, Antonia Furrer, Hannah Glover, Dardan Gashi, Melissa Carrillo, Yasushi Kondo, Robin T. Stipp, Georgii Khusainov, Karol Nass, Dmitry Ozerov, Claudio Cirelli, Philip J. M. Johnson, Florian Dworkowski, John H. Beale, Scott Stubbs, Thierry Zamofing, Marco Schneider, Kristina Krauskopf, Li Gao, Oliver Thorn-Seshold, Christoph Bostedt, Camila Bacellar, Michel O. Steinmetz, Christopher Milne, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Serial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experi
Externí odkaz:
https://doaj.org/article/f224092cc9184c46b2af0e3942817cf2
Autor:
Maximilian Wranik, Tobias Weinert, Chavdar Slavov, Tiziana Masini, Antonia Furrer, Natacha Gaillard, Dario Gioia, Marco Ferrarotti, Daniel James, Hannah Glover, Melissa Carrillo, Demet Kekilli, Robin Stipp, Petr Skopintsev, Steffen Brünle, Tobias Mühlethaler, John Beale, Dardan Gashi, Karol Nass, Dmitry Ozerov, Philip J. M. Johnson, Claudio Cirelli, Camila Bacellar, Markus Braun, Meitian Wang, Florian Dworkowski, Chris Milne, Andrea Cavalli, Josef Wachtveitl, Michel O. Steinmetz, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Photopharmacology manipulates the biological activity of small molecules by light. Using an X-ray laser, the authors follow the release of the drug azo-combretastatin A4 from tubulin and the concomitant structural changes over nine orders of magnitud
Externí odkaz:
https://doaj.org/article/31ccc9f5c1c7420b8b23b5fa45bdc9ee
Autor:
Karol Nass, Camila Bacellar, Claudio Cirelli, Florian Dworkowski, Yaroslav Gevorkov, Daniel James, Philip J. M. Johnson, Demet Kekilli, Gregor Knopp, Isabelle Martiel, Dmitry Ozerov, Alexandra Tolstikova, Laura Vera, Tobias Weinert, Oleksandr Yefanov, Jörg Standfuss, Sven Reiche, Christopher J. Milne
Publikováno v:
IUCrJ, Vol 8, Iss 6, Pp 905-920 (2021)
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables essentially radiation-damage-free macromolecular structure determination using microcrystals that are too small for synchrotron studies. However, SFX experiments o
Externí odkaz:
https://doaj.org/article/ad50bebd17b6464fb70fffcb3373aa32
Lipidic cubic phase serial femtosecond crystallography structure of a photosynthetic reaction centre
Autor:
Petra Båth, Analia Banacore, Per Börjesson, Robert Bosman, Cecilia Wickstrand, Cecilia Safari, Robert Dods, Swagatha Ghosh, Peter Dahl, Giorgia Ortolani, Tinna Björg Ulfarsdottir, Greger Hammarin, María-José García Bonete, Adams Vallejos, Lucija Ostojić, Petra Edlund, Johanna-Barbara Linse, Rebecka Andersson, Eriko Nango, Shigeki Owada, Rie Tanaka, Kensuke Tono, Yasumasa Joti, Osamu Nureki, Fangjia Luo, Daniel James, Karol Nass, Philip J. M. Johnson, Gregor Knopp, Dmitry Ozerov, Claudio Cirelli, Christopher Milne, So Iwata, Gisela Brändén, Richard Neutze
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:698-708
Serial crystallography is a rapidly growing method that can yield structural insights from microcrystals that were previously considered to be too small to be useful in conventional X-ray crystallography. Here, conditions for growing microcrystals of
Autor:
Camila Bacellar, Jérémy R. Rouxel, Rebecca A. Ingle, Giulia F. Mancini, Dominik Kinschel, Oliviero Cannelli, Yang Zhao, Claudio Cirelli, Gregor Knopp, Jakub Szlachetko, Frederico A. Lima, Samuel Menzi, Dmitry Ozerov, Georgios Pamfilidis, Katharina Kubicek, Dmitry Khakhulin, Wojciech Gawelda, Angel Rodriguez-Fernandez, Mykola Biednov, Christian Bressler, Christopher A. Arrell, Philip J. M. Johnson, Christopher J. Milne, Majed Chergui
We report femtosecond Fe K-edge absorption (XAS) and nonresonant X-ray emission (XES) spectra of ferric cytochrome C (Cyt c) upon excitation of the haem (>300 nm) or mixed excitation of the haem and tryptophan (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77088dc64aec3d3177ba4cdd9741ec67
http://hdl.handle.net/20.500.12614/3294
http://hdl.handle.net/20.500.12614/3294
Autor:
Thomas Gruhl, Tobias Weinert, Matthew Rodrigues, Christopher J Milne, Giorgia Ortolani, Karol Nass, Eriko Nango, Saumik Sen, Philip J M Johnson, Claudio Cirelli, Antonia Furrer, Sandra Mous, Petr Skopintsev, Daniel James, Florian Dworkowski, Petra Båth, Demet Kekilli, Dmitry Ozerov, Rie Tanaka, Hannah Glover, Camila Bacellar, Steffen Brünle, Cecilia M Casadei, Azeglio D Diethelm, Dardan Gashi, Guillaume Gotthard, Ramon Guixà-González, Yasumasa Joti, Victoria Kabanova, Gregor Knopp, Elena Lesca, Pikyee Ma, Isabelle Martiel, Jonas Mühle, Shigeki Owada, Filip Pamula, Daniel Sarabi, Oliver Tejero, Ching-Ju Tsai, Niranjan Varma, Anna Wach, Sébastien Boutet, Kensuke Tono, Przemyslaw Nogly, Xavier Deupi, So Iwata, Richard Neutze, Jörg Standfuss, Gebhard FX Schertler, Valerie Panneels
Vision is initiated by the rhodopsin family of light-sensitive G protein-coupled receptors (GPCRs). A photon is absorbed by the 11-cis retinal chromophore of rhodopsin, which isomerizes within 200 femtoseconds to the all-trans conformation, thereby i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6e4e1e23892118ac11c72f2ba04337
https://ruj.uj.edu.pl/xmlui/handle/item/312907
https://ruj.uj.edu.pl/xmlui/handle/item/312907
Autor:
Oleksandr Yefanov, A. Tolstikova, Demet Kekilli, Y. Gevorkov, Tobias Weinert, Claudio Cirelli, Camila Bacellar, Isabelle Martiel, Jörg Standfuss, Laura Vera, Dmitry Ozerov, Florian S. N. Dworkowski, Sven Reiche, Daniel James, Christopher J. Milne, Philip J. M. Johnson, Karol Nass, Gregor Knopp
Publikováno v:
IUCrJ, Vol 8, Iss 6, Pp 905-920 (2021)
IUCrJ
IUCrJ 8(6), 905-920 (2021). doi:10.1107/S2052252521008046
IUCrJ
IUCrJ 8(6), 905-920 (2021). doi:10.1107/S2052252521008046
IUCrJ 8(6), 905 - 920 (2021). doi:10.1107/S2052252521008046
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables essentially radiation-damage-free macromolecular structure determination using microcrystals that
Serial femtosecond crystallography (SFX) at X-ray free-electron lasers (XFELs) enables essentially radiation-damage-free macromolecular structure determination using microcrystals that
Autor:
Claudio Cirelli, Rafael Abela, Thomas J. Schmidt, Vladimir Arsov, Eduard Prat, Leonardo Sala, M. Aiba, B. Keil, Gian Luca Orlandi, Karol Nass, Luc Patthey, Marco Calvi, F. Marcellini, Rolf Follath, Terence Garvey, Daniela Kiselev, Martin Paraliev, Alexander Dietrich, Christian Erny, Steven L. Johnson, Albert Romann, Arturo Alarcon, Peter Radi, Henrik T. Lemke, Micha Dehler, Pavel Chevtsov, Bruce D. Patterson, Martin Huppert, Maik Kaiser, J. Alex, Jean-Yves Raguin, S. Redford, Christoph Kittel, Mathias Sander, Fabian Märki, Christopher Arrell, Jens Rehanek, Zheqiao Geng, Thomas Schietinger, A. Wrulich, Claude Pradervand, Simona Bettoni, Roger Biffiger, Simon Ebner, Elke Zimoch, Cigdem Ozkan Loch, Sladana Dordevic, Majed Chergui, C. Svetina, Gregor Knopp, Vincent Esposito, D. Treyer, Roger Kalt, C. Gough, A. Trisorio, A. Hauff, Paul Beaud, Hans-Heinrich Braun, Alexandre Gobbo, G. Marinkovic, Roberto Dinapoli, Rasmus Ischebeck, Marco Pedrozzi, Daniel Llorente Sancho, W. Koprek, Alexander Malyzhenkov, Eugenio Ferrari, Leonid Rivkin, Philip J. M. Johnson, Yunieski Arbelo, Romain Ganter, Mike Seidel, Carlo Vicario, A. Citterio, Roman Mankowsky, Gerhard Ingold, L. Stingelin, F. Frei, M. Bopp, Carl Beard, Stephan Hunziker, Florian Löhl, Ariana Cassar, Volker Schlott, Philipp Dijkstal, Paolo Craievich, Didier Voulot, Giulia F. Mancini, Sven Reiche, Daniel Engeler, Aldo Mozzanica, Pavle Juranić, Andreas Dax, Uwe Flechsig, Christopher J. Milne, Serhane Zerdane, Markus Janousch, Yunpei Deng, M. Jurcevic, Isabelle Martiel, Nicole Hiller, Tine Celcer, T. Schilcher, Christoph P. Hauri, Michael Laznovsky, M. Stadler, Bill Pedrini, Camila Bacellar, Marta Csatari Divall
Publikováno v:
Nature Photonics. 14:748-754
We present the first lasing results of SwissFEL, a hard X-ray free-electron laser (FEL) that recently came into operation at the Paul Scherrer Institute in Switzerland. SwissFEL is a very stable, compact and cost-effective X-ray FEL facility driven b