Correlation of refractive index based and THz streaking arrival time tools for a hard X-ray free-electron laser

Autor: Wojciech Błachucki, Philip J. M. Johnson, Ivan Usov, Edwin Divall, Claudio Cirelli, Gregor Knopp, Pavle Juranić, Luc Patthey, Jakub Szlachetko, Henrik Lemke, Christopher Milne, Christopher Arrell

Publikováno v: Journal of Synchrotron Radiation, Vol 31, Iss 2, Pp 233-242 (2024)

To fully exploit ultra-short X-ray pulse durations routinely available at X-ray free-electron lasers to follow out-of-equilibrium dynamics, inherent arrival time fluctuations of the X-ray pulse with an external perturbing laser pulse need to be measu

Externí odkaz: https://doaj.org/article/72348668dc404a1d816e610e3916cebb

Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography

Autor: Maximilian Wranik, Tobias Weinert, Chavdar Slavov, Tiziana Masini, Antonia Furrer, Natacha Gaillard, Dario Gioia, Marco Ferrarotti, Daniel James, Hannah Glover, Melissa Carrillo, Demet Kekilli, Robin Stipp, Petr Skopintsev, Steffen Brünle, Tobias Mühlethaler, John Beale, Dardan Gashi, Karol Nass, Dmitry Ozerov, Philip J. M. Johnson, Claudio Cirelli, Camila Bacellar, Markus Braun, Meitian Wang, Florian Dworkowski, Chris Milne, Andrea Cavalli, Josef Wachtveitl, Michel O. Steinmetz, Jörg Standfuss

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

Photopharmacology manipulates the biological activity of small molecules by light. Using an X-ray laser, the authors follow the release of the drug azo-combretastatin A4 from tubulin and the concomitant structural changes over nine orders of magnitud

Externí odkaz: https://doaj.org/article/31ccc9f5c1c7420b8b23b5fa45bdc9ee

Lipidic cubic phase serial femtosecond crystallography structure of a photosynthetic reaction centre

Autor: Petra Båth, Analia Banacore, Per Börjesson, Robert Bosman, Cecilia Wickstrand, Cecilia Safari, Robert Dods, Swagatha Ghosh, Peter Dahl, Giorgia Ortolani, Tinna Björg Ulfarsdottir, Greger Hammarin, María-José García Bonete, Adams Vallejos, Lucija Ostojić, Petra Edlund, Johanna-Barbara Linse, Rebecka Andersson, Eriko Nango, Shigeki Owada, Rie Tanaka, Kensuke Tono, Yasumasa Joti, Osamu Nureki, Fangjia Luo, Daniel James, Karol Nass, Philip J. M. Johnson, Gregor Knopp, Dmitry Ozerov, Claudio Cirelli, Christopher Milne, So Iwata, Gisela Brändén, Richard Neutze

Publikováno v: Acta Crystallographica Section D Structural Biology. 78:698-708

Serial crystallography is a rapidly growing method that can yield structural insights from microcrystals that were previously considered to be too small to be useful in conventional X-ray crystallography. Here, conditions for growing microcrystals of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1f5a91eac8f35496a07f4ecfc7a445
https://doi.org/10.1107/s2059798322004144

Ultrafast structural changes direct the first molecular events of vision

Autor: Thomas Gruhl, Tobias Weinert, Matthew Rodrigues, Christopher J Milne, Giorgia Ortolani, Karol Nass, Eriko Nango, Saumik Sen, Philip J M Johnson, Claudio Cirelli, Antonia Furrer, Sandra Mous, Petr Skopintsev, Daniel James, Florian Dworkowski, Petra Båth, Demet Kekilli, Dmitry Ozerov, Rie Tanaka, Hannah Glover, Camila Bacellar, Steffen Brünle, Cecilia M Casadei, Azeglio D Diethelm, Dardan Gashi, Guillaume Gotthard, Ramon Guixà-González, Yasumasa Joti, Victoria Kabanova, Gregor Knopp, Elena Lesca, Pikyee Ma, Isabelle Martiel, Jonas Mühle, Shigeki Owada, Filip Pamula, Daniel Sarabi, Oliver Tejero, Ching-Ju Tsai, Niranjan Varma, Anna Wach, Sébastien Boutet, Kensuke Tono, Przemyslaw Nogly, Xavier Deupi, So Iwata, Richard Neutze, Jörg Standfuss, Gebhard FX Schertler, Valerie Panneels

Vision is initiated by the rhodopsin family of light-sensitive G protein-coupled receptors (GPCRs). A photon is absorbed by the 11-cis retinal chromophore of rhodopsin, which isomerizes within 200 femtoseconds to the all-trans conformation, thereby i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6e4e1e23892118ac11c72f2ba04337
https://ruj.uj.edu.pl/xmlui/handle/item/312907

A compact and cost-effective hard X-ray free-electron laser driven by a high-brightness and low-energy electron beam

Autor: Claudio Cirelli, Rafael Abela, Thomas J. Schmidt, Vladimir Arsov, Eduard Prat, Leonardo Sala, M. Aiba, B. Keil, Gian Luca Orlandi, Karol Nass, Luc Patthey, Marco Calvi, F. Marcellini, Rolf Follath, Terence Garvey, Daniela Kiselev, Martin Paraliev, Alexander Dietrich, Christian Erny, Steven L. Johnson, Albert Romann, Arturo Alarcon, Peter Radi, Henrik T. Lemke, Micha Dehler, Pavel Chevtsov, Bruce D. Patterson, Martin Huppert, Maik Kaiser, J. Alex, Jean-Yves Raguin, S. Redford, Christoph Kittel, Mathias Sander, Fabian Märki, Christopher Arrell, Jens Rehanek, Zheqiao Geng, Thomas Schietinger, A. Wrulich, Claude Pradervand, Simona Bettoni, Roger Biffiger, Simon Ebner, Elke Zimoch, Cigdem Ozkan Loch, Sladana Dordevic, Majed Chergui, C. Svetina, Gregor Knopp, Vincent Esposito, D. Treyer, Roger Kalt, C. Gough, A. Trisorio, A. Hauff, Paul Beaud, Hans-Heinrich Braun, Alexandre Gobbo, G. Marinkovic, Roberto Dinapoli, Rasmus Ischebeck, Marco Pedrozzi, Daniel Llorente Sancho, W. Koprek, Alexander Malyzhenkov, Eugenio Ferrari, Leonid Rivkin, Philip J. M. Johnson, Yunieski Arbelo, Romain Ganter, Mike Seidel, Carlo Vicario, A. Citterio, Roman Mankowsky, Gerhard Ingold, L. Stingelin, F. Frei, M. Bopp, Carl Beard, Stephan Hunziker, Florian Löhl, Ariana Cassar, Volker Schlott, Philipp Dijkstal, Paolo Craievich, Didier Voulot, Giulia F. Mancini, Sven Reiche, Daniel Engeler, Aldo Mozzanica, Pavle Juranić, Andreas Dax, Uwe Flechsig, Christopher J. Milne, Serhane Zerdane, Markus Janousch, Yunpei Deng, M. Jurcevic, Isabelle Martiel, Nicole Hiller, Tine Celcer, T. Schilcher, Christoph P. Hauri, Michael Laznovsky, M. Stadler, Bill Pedrini, Camila Bacellar, Marta Csatari Divall

Publikováno v: Nature Photonics. 14:748-754

We present the first lasing results of SwissFEL, a hard X-ray free-electron laser (FEL) that recently came into operation at the Paul Scherrer Institute in Switzerland. SwissFEL is a very stable, compact and cost-effective X-ray FEL facility driven b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21444ae8eb2f56bf35cd503ebc4adf35
https://doi.org/10.1038/s41566-020-00712-8