Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Philip J, Thompson"'
Autor:
Sarah Grosche, Ingo Marenholz, Jorge Esparza-Gordillo, Aleix Arnau-Soler, Erola Pairo-Castineira, Franz Rüschendorf, Tarunveer S. Ahluwalia, Catarina Almqvist, Andreas Arnold, Australian Asthma Genetics Consortium (AAGC), Hansjörg Baurecht, Hans Bisgaard, Klaus Bønnelykke, Sara J. Brown, Mariona Bustamante, John A. Curtin, Adnan Custovic, Shyamali C. Dharmage, Ana Esplugues, Mario Falchi, Dietmar Fernandez-Orth, Manuel A. R. Ferreira, Andre Franke, Sascha Gerdes, Christian Gieger, Hakon Hakonarson, Patrick G. Holt, Georg Homuth, Norbert Hubner, Pirro G. Hysi, Marjo-Riitta Jarvelin, Robert Karlsson, Gerard H. Koppelman, Susanne Lau, Manuel Lutz, Patrik K. E. Magnusson, Guy B. Marks, Martina Müller-Nurasyid, Markus M. Nöthen, Lavinia Paternoster, Craig E. Pennell, Annette Peters, Konrad Rawlik, Colin F. Robertson, Elke Rodriguez, Sylvain Sebert, Angela Simpson, Patrick M. A. Sleiman, Marie Standl, Dora Stölzl, Konstantin Strauch, Agnieszka Szwajda, Albert Tenesa, Philip J. Thompson, Vilhelmina Ullemar, Alessia Visconti, Judith M. Vonk, Carol A. Wang, Stephan Weidinger, Matthias Wielscher, Catherine L. Worth, Chen-Jian Xu, Young-Ae Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Genetic studies of eczema to date have mostly explored common genetic variation. Here, the authors perform a large meta-analysis for common and rare variants and discover 8 loci associated with eczema. Over 20% of the heritability of the condition is
Externí odkaz:
https://doaj.org/article/d54f293b9f924ec89242fe90b53feed8
Autor:
Cecilia M. Prêle, Thomas Iosifidis, Robin J. McAnulty, David R. Pearce, Bahareh Badrian, Tylah Miles, Sarra E. Jamieson, Matthias Ernst, Philip J. Thompson, Geoffrey J. Laurent, Darryl A. Knight, Steven E. Mutsaers
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 498 (2021)
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and functi
Externí odkaz:
https://doaj.org/article/f48fa198e8004c7484e59b7e0c37a1fd
Autor:
Kerry L Hancock, Sinthia Bosnic-Anticevich, John D Blakey, Mark Hew, Li Ping Chung, Biljana Cvetkovski, Scott Claxton, Peter Del Fante, Eve Denton, Joe Doan, Kanchanamala Ranasinghe, Lucy Morgan, Anita Sharma, Peter K Smith, Deb Stewart, Philip J Thompson, Russell Wiseman, John W Upham, Kwok Y Yan, Victoria Carter, Kiranjeet Dhillon, Florian Heraud, Thao Le, Rebecca Vella, David Price
Publikováno v:
Pragmatic and Observational Research.
Kerry L Hancock,1 Sinthia Bosnic-Anticevich,2â 4 John D Blakey,5,6 Mark Hew,7,8 Li Ping Chung,9 Biljana Cvetkovski,3 Scott Claxton,10 Peter Del Fante,11 Eve Denton,7,8 Joe Doan,12 Kanchanamala Ranasinghe,13,14 Lucy Morgan,15â 17 Anita Sharm
Autor:
Philip J. Thompson, Gerard J. Criner, Mark T. Dransfield, David M. G. Halpin, MeiLan K. Han, David A. Lipson, Ghassan J. Maghzal, Fernando J. Martinez, Dawn Midwinter, Dave Singh, Lee Tombs, Robert A. Wise
Publikováno v:
Respirology (Carlton, Vic.)REFERENCES. 27(12)
Chronic mucus hypersecretion (CMH) is a clinical phenotype of COPD. This exploratory post hoc analysis assessed relationship between CMH status and treatment response in IMPACT.Patients were randomized to once-daily fluticasone furoate/umeclidinium/v
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87175 (2014)
The kinin B₁ receptor (B₁R) is rapidly upregulated after tissue trauma or inflammation and is involved in cancer and inflammatory diseases such as asthma. However, the role of the: promoter; a postulated alternative promoter; and spliced variants
Externí odkaz:
https://doaj.org/article/1cfdd25b2eb94828bcacfb1f955a475d
Autor:
Li Ping Chung, Svetlana Baltic, Manuel Ferreira, Suzanna Temple, Grant Waterer, Philip J Thompson
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93695 (2014)
BACKGROUND: β2 adrenergic receptor (ADRβ2) polymorphisms including ADRβ2+46G>A have been reported to cause adverse outcomes in mild asthmatics. The extent to which ADRβ2 polymorphisms and in particular their haplotypes contribute to severe asthma
Externí odkaz:
https://doaj.org/article/d97e0a8ec7544e8994c9f5f93c4d8e6a
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 10, Pp 1706-1713 (2001)
Phospholipase A2 (PLA2) activity is usually assayed with expensive radioactive or chromogenic substrates unsuitable for performing large numbers of assays. We have designed a simple microplate assay for human serum PLA2 using the chromogenic substrat
Externí odkaz:
https://doaj.org/article/2f678a61b4344a69b6fdbfdde3278097
Autor:
Geoffrey J. Laurent, Philip J. Thompson, David R. Pearce, Sarra E. Jamieson, Matthias Ernst, Tylah Miles, Cecilia M Prêle, Robin J. McAnulty, Darryl A. Knight, Bahareh Badrian, Steven E. Mutsaers, Thomas Iosifidis
Publikováno v:
Biomedicines, Vol 9, Iss 498, p 498 (2021)
Biomedicines
Volume 9
Issue 5
Biomedicines
Volume 9
Issue 5
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and functi
Autor:
Adaikalavan Ramasamy, Mikko Kuokkanen, Sailaja Vedantam, Zofia K Gajdos, Alexessander Couto Alves, Helen N Lyon, Manuel A R Ferreira, David P Strachan, Jing Hua Zhao, Michael J Abramson, Matthew A Brown, Lachlan Coin, Shyamali C Dharmage, David L Duffy, Tari Haahtela, Andrew C Heath, Christer Janson, Mika Kähönen, Kay-Tee Khaw, Jaana Laitinen, Peter Le Souef, Terho Lehtimäki, Australian Asthma Genetics Consortium collaborators, Pamela A F Madden, Guy B Marks, Nicholas G Martin, Melanie C Matheson, Cameron D Palmer, Aarno Palotie, Anneli Pouta, Colin F Robertson, Jorma Viikari, Elisabeth Widen, Matthias Wjst, Deborah L Jarvis, Grant W Montgomery, Philip J Thompson, Nick Wareham, Johan Eriksson, Pekka Jousilahti, Tarja Laitinen, Juha Pekkanen, Olli T Raitakari, George T O'Connor, Veikko Salomaa, Marjo-Riitta Jarvelin, Joel N Hirschhorn
Publikováno v:
PLoS ONE, Vol 8, Iss 3 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0044008.].
Externí odkaz:
https://doaj.org/article/731bc0c9a5f74d86b5e0ca5199bfcf97
Autor:
Chuan Bian Lim, Cecilia M Prêle, Hui Min Cheah, Yuen Yee Cheng, Sonja Klebe, Glen Reid, D Neil Watkins, Svetlana Baltic, Philip J Thompson, Steven E Mutsaers
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66685 (2013)
BACKGROUND: The Hedgehog (HH) signaling pathway is critical for embryonic development and adult homeostasis. Recent studies have identified regulatory roles for this pathway in certain cancers with mutations in the HH pathway genes. The extent to whi
Externí odkaz:
https://doaj.org/article/8fb1acf1b01742ddb64b80e1669bc29c