Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Philip J, Hogarth"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Two strains of mice (BALB/c and CB6F1) were vaccinated with a range of Bacille Calmette-Guérin (BCG) Danish doses from 3 × 105 to 30 CFU/mouse, followed by aerosol infection with Mtb (H37Rv or West-Beijing HN878 strain). The results indica
Externí odkaz:
https://doaj.org/article/5a06714d4d7341239fefee3d1d60308b
Autor:
Andries J van Tonder, Mark J Thornton, Andrew J K Conlan, Keith A Jolley, Lee Goolding, Andrew P Mitchell, James Dale, Eleftheria Palkopoulou, Philip J Hogarth, R Glyn Hewinson, James L N Wood, Julian Parkhill
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010075 (2021)
Mycobacterium bovis (M. bovis) is a causative agent of bovine tuberculosis, a significant source of morbidity and mortality in the global cattle industry. The Randomised Badger Culling Trial was a field experiment carried out between 1998 and 2005 in
Externí odkaz:
https://doaj.org/article/c0ee380f21ef4c2ab4ccb3c347258a16
Autor:
Satadru Sekhar Mandal, Lucy Duncombe, N. Vijaya Ganesh, Susmita Sarkar, Laurence Howells, Philip J. Hogarth, David R. Bundle, John McGiven
Publikováno v:
ACS Central Science, Vol 3, Iss 3, Pp 224-231 (2017)
Externí odkaz:
https://doaj.org/article/297c344b2daf4e3aa5c16ef444736cda
Autor:
Rowan P Morris, Teresa Montoya, Natasha Price, Babita Nicklin, Philip J Hogarth, Jo Mayers, Jason Sawyer, Adrian McGoldrick
Publikováno v:
Journal of Applied Microbiology. 134
AimsDevelopment and validation of a real-time PCR test for high-throughput routine screening of animal tissue for Mycobacterium bovis and other Mycobacterium tuberculosis complex (MTBC) members.Methods and resultsA preliminary study compared the resu
Autor:
Pedro J. Sánchez-Cordón, John Spiropoulos, Daryan A. Kaveh, Philip J. Hogarth, M. Carmen Garcia-Pelayo, Naomi Bull
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Heterologous BCG prime-boost regimens represent a promising strategy for an urgently required improved tuberculosis vaccine. Identifying the mechanisms which underpin the enhanced protection induced by such strategies is one key aim which would signi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Two strains of mice (BALB/c and CB6F1) were vaccinated with a range of Bacille Calmette-Guérin (BCG) Danish doses from 3 × 105to 30 CFU/mouse, followed by aerosol infection withMtb(H37Rv or West-Beijing HN878 strain). The results indicated that bot
Autor:
Lee Goolding, James L. N. Wood, R. Glyn Hewinson, Keith A. Jolley, Mark J. Thornton, Philip J. Hogarth, Andrew J. K. Conlan, Eleftheria Palkopoulou, James Dale, Andries J. van Tonder, Julian Parkhill, Andrew Mitchell
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 11, p e1010075 (2021)
PLoS Pathogens, Vol 17, Iss 11, p e1010075 (2021)
Mycobacterium bovis (M. bovis) is a causative agent of bovine tuberculosis, a significant source of morbidity and mortality in the global cattle industry. The Randomised Badger Culling Trial was a field experiment carried out between 1998 and 2005 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ffa32f900a6411702411958a028083
https://www.repository.cam.ac.uk/handle/1810/332426
https://www.repository.cam.ac.uk/handle/1810/332426
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38926 (2012)
The assessment of antigen-specific T cell responses by intracellular cytokine staining (ICS) has become a routine technique in studies of vaccination and immunity. Here, we highlight how the duration of in vitro antigen pre-stimulation, combined with
Externí odkaz:
https://doaj.org/article/0b351fe853c54c89a66f4abdd7482a8d
Autor:
Elihu Aranday-Cortes, Philip J Hogarth, Daryan A Kaveh, Adam O Whelan, Bernardo Villarreal-Ramos, Ajit Lalvani, H Martin Vordermeier
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30626 (2012)
Bovine tuberculosis (bTb) remains a major and economically important disease of livestock. Improved ante-mortem diagnostic tools would help to underpin novel control strategies. The definition of biomarkers correlating with disease progression could
Externí odkaz:
https://doaj.org/article/9368a9a57b614fe9bd54d67f9cce33c7
Autor:
Alejandro Núñez, Alexander N. Civello, Philip J. Hogarth, Pedro J. Sánchez-Cordón, Colin P.D. Birch, D. Hicks, John Spiropoulos
Publikováno v:
Vaccine. 38(30)
In order to develop improved vaccinations against tuberculosis, it is essential to understand the effect of vaccination on the immune response, and to overcome the mechanisms by which mycobacteria regulate this immune response. In this study, we exam