Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Philip H. Gutin"'
Autor:
Ingo K. Mellinghoff, Lisa M. DeAngelis, Nikolaus Schultz, Thomas G. Graeber, Katherine S. Panageas, Jason T. Huse, Philip H. Gutin, Anne S. Reiner, Vaios Hatzoglou, Enrico C. Lallana, Scott Peak, Jon Glass, Minhee Won, Ahmet Dogan, Julia Wolfe, Craig H. Moskowitz, Craig S. Sauter, Paul Hamlin, M. Lia Palomba, Ariela Noy, Elina Tsyvkin, Alissa A. Thomas, Elena Pentsova, Antonio Omuro, Craig P. Nolan, Thomas J. Kaley, Igor T. Gavrilovic, Cameron W. Brennan, Viviane S. Tabar, Agnes Viale, Marc Rosenblum, Dan Rohle, Wan-Ying Hsieh, Owen Clark, Donna Nichol, Paolo Codega, Derrek Schartz, Carl Campos, Sarah S. Tang, Nicolaos Palaskas, Alessandro Pastore, Christian Grommes
Supplementary Methods. Supplementary Table S1: Baseline characteristics of PCNSL Patients. Supplementary Table S2: Baseline characteristics of SCNSL patients. Supplementary Table S3: Corticosteroid use. Supplementary Table S4: Genes with Recurrent Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846702464e3ab3c289e6186006db05bc
https://doi.org/10.1158/2159-8290.22532099
https://doi.org/10.1158/2159-8290.22532099
Autor:
Barry S. Taylor, Ingo K. Mellinghoff, Lisa M. DeAngelis, Marc Rosenblum, Cameron W. Brennan, Viviane S. Tabar, Timothy A. Chan, Philip H. Gutin, Alexandra M. Miller, Anna F. Piotrowski, Mariza Daras, Adrienne Boire, Christian Grommes, Jacqueline B. Stone, Eli L. Diamond, Thomas J. Kaley, Igor T. Gavrilovic, Antonio Omuro, Elena Pentsova, Craig P. Nolan, T. Jonathan Yang, Kathryn Beal, Allison Hyde, Malbora Manne, Andrew T. McKeown, Shweta S. Chavan, Shahiba Q. Ogilvie, Maryam Pourmaleki, Juliann Chmielecki, Michael E. Goldberg, Diana Mandelker, Zsofia K. Stadler, Angela G. Arnold, David B. Solit, Marc Ladanyi, Ahmet Zehir, Michael F. Berger, Bob T. Li, David M. Hyman, Natalie M. DiStefano, Robert J. Young, Andrew L. Lin, Philip Jonsson
Figure S1: Distribution of systemic therapies received. Figure S2: Number of sequenced samples per patient. Figure S3: Subgroup-defining genomic lesions in IDH-wildtype and -mutant gliomas. Figure S4: Frequency of mutations in primary tumors. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4027dff8635107fa41557a7b76e27f
https://doi.org/10.1158/1078-0432.22472186
https://doi.org/10.1158/1078-0432.22472186
Autor:
Barry S. Taylor, Ingo K. Mellinghoff, Lisa M. DeAngelis, Marc Rosenblum, Cameron W. Brennan, Viviane S. Tabar, Timothy A. Chan, Philip H. Gutin, Alexandra M. Miller, Anna F. Piotrowski, Mariza Daras, Adrienne Boire, Christian Grommes, Jacqueline B. Stone, Eli L. Diamond, Thomas J. Kaley, Igor T. Gavrilovic, Antonio Omuro, Elena Pentsova, Craig P. Nolan, T. Jonathan Yang, Kathryn Beal, Allison Hyde, Malbora Manne, Andrew T. McKeown, Shweta S. Chavan, Shahiba Q. Ogilvie, Maryam Pourmaleki, Juliann Chmielecki, Michael E. Goldberg, Diana Mandelker, Zsofia K. Stadler, Angela G. Arnold, David B. Solit, Marc Ladanyi, Ahmet Zehir, Michael F. Berger, Bob T. Li, David M. Hyman, Natalie M. DiStefano, Robert J. Young, Andrew L. Lin, Philip Jonsson
Table S1: Patient-level clinical annotation. Table S2: Sample-level clinical annotation. Table S3: Patient-level treatment lines. Table S4: Gene panels for targeted sequencing. Table S5: Somatic mutations. Table S6: Gene-level copy number alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac7a093f2982213652b140852cf8ccb
https://doi.org/10.1158/1078-0432.22472180.v1
https://doi.org/10.1158/1078-0432.22472180.v1
Autor:
Barry S. Taylor, Ingo K. Mellinghoff, Lisa M. DeAngelis, Marc Rosenblum, Cameron W. Brennan, Viviane S. Tabar, Timothy A. Chan, Philip H. Gutin, Alexandra M. Miller, Anna F. Piotrowski, Mariza Daras, Adrienne Boire, Christian Grommes, Jacqueline B. Stone, Eli L. Diamond, Thomas J. Kaley, Igor T. Gavrilovic, Antonio Omuro, Elena Pentsova, Craig P. Nolan, T. Jonathan Yang, Kathryn Beal, Allison Hyde, Malbora Manne, Andrew T. McKeown, Shweta S. Chavan, Shahiba Q. Ogilvie, Maryam Pourmaleki, Juliann Chmielecki, Michael E. Goldberg, Diana Mandelker, Zsofia K. Stadler, Angela G. Arnold, David B. Solit, Marc Ladanyi, Ahmet Zehir, Michael F. Berger, Bob T. Li, David M. Hyman, Natalie M. DiStefano, Robert J. Young, Andrew L. Lin, Philip Jonsson
Purpose:The genomic landscape of gliomas has been characterized and now contributes to disease classification, yet the relationship between molecular profile and disease progression and treatment response remain poorly understood.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641951579cd359e3e5caf9da91b7120d
https://doi.org/10.1158/1078-0432.c.6528149
https://doi.org/10.1158/1078-0432.c.6528149
Autor:
Barry S. Taylor, Ingo K. Mellinghoff, Lisa M. DeAngelis, Marc Rosenblum, Cameron W. Brennan, Viviane S. Tabar, Timothy A. Chan, Philip H. Gutin, Alexandra M. Miller, Anna F. Piotrowski, Mariza Daras, Adrienne Boire, Christian Grommes, Jacqueline B. Stone, Eli L. Diamond, Thomas J. Kaley, Igor T. Gavrilovic, Antonio Omuro, Elena Pentsova, Craig P. Nolan, T. Jonathan Yang, Kathryn Beal, Allison Hyde, Malbora Manne, Andrew T. McKeown, Shweta S. Chavan, Shahiba Q. Ogilvie, Maryam Pourmaleki, Juliann Chmielecki, Michael E. Goldberg, Diana Mandelker, Zsofia K. Stadler, Angela G. Arnold, David B. Solit, Marc Ladanyi, Ahmet Zehir, Michael F. Berger, Bob T. Li, David M. Hyman, Natalie M. DiStefano, Robert J. Young, Andrew L. Lin, Philip Jonsson
List of Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b012a1aef7c35ac455292434f5b79f
https://doi.org/10.1158/1078-0432.22472183.v1
https://doi.org/10.1158/1078-0432.22472183.v1
Autor:
Maya S. Graham, Heiko Schöder, Neil H. Bander, Joseph A. O'Donoghue, Michael R. McDevitt, Sean D. Carlin, Simone Krebs, Christian Grommes, Joseph R. Osborne, Robert J. Young, Philip H. Gutin
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:783-785
Autor:
Robert J. Young, Philip H. Gutin, Kathryn Beal, Jason T. Huse, Viviane Tabar, Pat Zanzonico, Heiko Schöder, Zachary A. Kohutek, Bradley J. Beattie, John L. Humm, Milan Grkovski, Zhigang Zhang, Cameron Brennan, Marc K. Rosenblum, Ronald G. Blasberg
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 47:1446-1457
Radiographic changes of brain metastases after stereotactic radiosurgery (SRS) can signify tumor recurrence and/or radiation necrosis (RN); however, standard imaging modalities cannot easily distinguish between these two entities. We investigated whe
Autor:
Qiren Liang, S. Kyun Lim, Viviane Tabar, Noelle S. Williams, Hua Yu Wang, Xuanhua Xie, Yu Jung Chen, Yufeng Shi, Swathi V. Iyer, Daochun Sun, Philip H. Gutin, Jef K. De Brabander, Luis F. Parada, Zilai Wang
Publikováno v:
Nature
Cancer-specific inhibitors that reflect the unique metabolic needs of cancer cells are rare. Here we describe Gboxin, a small molecule that specifically inhibits the growth of primary mouse and human glioblastoma cells but not that of mouse embryonic
Autor:
Simone Krebs, Christian Grommes, Michael R. McDevitt, Sean D. Carlin, Joseph A. O’Donoghue, Maya S. Graham, Robert J. Young, Heiko Schöder, Philip H. Gutin, Neil H. Bander, Joseph R. Osborne
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:2102-2102
Autor:
Klara Soukup, Sina Nassiri, Roy Thomas Daniel, Viviane Tabar, Cameron Brennan, Johanna A. Joyce, Mara Kornete, Jean-Philippe Brouland, Robert L. Bowman, Florian Klemm, Christine A. Iacobuzio-Donahue, Roeltje R. Maas, Monika E. Hegi, Philip H. Gutin
Publikováno v:
Cell, vol. 181, no. 7, pp. 1643-1660.e17
Cell
Cell
Brain malignancies encompass a range of primary and metastatic cancers, including low-grade and high-grade gliomas and brain metastases (BrMs) originating from diverse extracranial tumors. Our understanding of the brain tumor microenvironment (TME) r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89eb8ac1f8338913b832b55314e40f36
https://serval.unil.ch/resource/serval:BIB_B25384BE18E8.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_B25384BE18E8.P001/REF.pdf