Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Philip G. Bardin"'
Autor:
Grace Yap, Laurence E. Ruane, Kais Hamza, Elizabeth Leahy, Adriana Avram, Malcolm Baxter, Joo Koh, Philip G. Bardin, Paul Leong
Publikováno v:
ERJ Open Research, Vol 9, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/943af82669904039b0579c25d57bca2d
Autor:
Paul Leong, Anne E. Vertigan, Mark Hew, Malcolm Baxter, Debra Phyland, James H. Hull, Thomas L. Carroll, Peter G. Gibson, Vanessa M. McDonald, Philip G. Bardin
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Introduction Currently there is no consistent and widely accepted approach to the diagnosis of vocal cord dysfunction/inducible laryngeal obstruction (VCD/ILO). Harmonised diagnostic methods are vital to enable optimal diagnosis, advance management a
Externí odkaz:
https://doaj.org/article/4f0b6a176c614e2f960d5491cae98440
Autor:
Martin I. MacDonald, Christian R. Osadnik, Lauren Bulfin, Elizabeth Leahy, Paul Leong, Eskandarain Shafuddin, Kais Hamza, Paul T. King, Philip G. Bardin
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Background The generic term “exacerbation” does not reflect the heterogeneity of acute exacerbations of COPD (AECOPD). We utilised a novel algorithmic strategy to profile exacerbation phenotypes based on underlying aetiologies. Methods Patients h
Externí odkaz:
https://doaj.org/article/52a69679e4dc475b8125b9148702603f
Autor:
Lydia Cvejic, Nadine Guiney, Kenneth K. Lau, Paul Finlay, Kais Hamza, Paul Leong, Martin MacDonald, Paul T. King, Philip G. Bardin
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Externí odkaz:
https://doaj.org/article/557ff86de86944c8a92c30f44466fbc0
Autor:
Paul T. King, Lovisa Dousha, Nadeene Clarke, Jennifer Schaefer, Rosemary Carzino, Roleen Sharma, Ken L. Wan, Aveena Anantharajah, Kim O'Sullivan, Zhong X. Lu, Stephen R. Holdsworth, Sarath Ranganathan, Philip G. Bardin, David S. Armstrong
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Childhood lung infection is often associated with prominent neutrophilic airway inflammation and excess production of proteases such as neutrophil elastase (NE). The mechanisms responsible for this inflammation are not well understood. One potentiall
Externí odkaz:
https://doaj.org/article/117403dc98d74041be104999276d522c
Autor:
Reena Ghildyal, Michael N. Teng, Kim C. Tran, John Mills, Marco G. Casarotto, Philip G. Bardin, David A. Jans
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7976 (2022)
Respiratory syncytial virus (RSV) is a major cause of respiratory infections in infants and the elderly. Although the RSV matrix (M) protein has key roles in the nucleus early in infection, and in the cytoplasm later, the molecular basis of switching
Externí odkaz:
https://doaj.org/article/12c2b8e768624e24aed6f50d71d51a84
Autor:
Paul Leong, Martin I. MacDonald, Paul T. King, Christian R. Osadnik, Brian S. Ko, Shane A. Landry, Kais Hamza, Ahilan Kugenasan, John M. Troupis, Philip G. Bardin
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Introduction Acute exacerbations of COPD (AECOPD) are accompanied by escalations in cardiac risk superimposed upon elevated baseline risk. Appropriate treatment for coronary artery disease (CAD) and heart failure with reduced ejection fraction (HFrEF
Externí odkaz:
https://doaj.org/article/b352609a5a714f5caf7b4e7fcb391b11
Autor:
Lydia Cvejic, Nadine Guiney, Tiffany Nicholson, Kenneth K. Lau, Paul Finlay, Kais Hamza, Christian Osadnik, Paul Leong, Martin MacDonald, Paul T. King, Philip G. Bardin
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Rationale Swallow may be compromised in COPD leading to aspiration and adverse respiratory consequences. However, prevalence and consequences of detectable aspiration in stable COPD are not known. Objectives We tested the hypothesis that a significan
Externí odkaz:
https://doaj.org/article/b49c77f8c0494e0ba5f3fe46f54533b4
Autor:
Paul Leong, Anne Tran, Jhanavi Rangaswamy, Laurence E. Ruane, Michael W. Fernando, Martin I. MacDonald, Kenneth K. Lau, Philip G. Bardin
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Background Tracheal obstruction resulting from expiratory tracheal deformation has been associated with respiratory symptoms and severe airway exacerbations. In chronic obstructive pulmonary disease (COPD), acute exacerbations (AECOPD) creat
Externí odkaz:
https://doaj.org/article/a9b1caa5bb0c4851aca8e3f9c48d1c0c
Autor:
Geneviève Pépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R. G. Williams, Michael P. Gantier
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT Inflammatory responses, while essential for pathogen clearance, can also be deleterious to the host. Chemical inhibition of topoisomerase 1 (Top1) by low-dose camptothecin (CPT) can suppress transcriptional induction of antiviral and inflamm
Externí odkaz:
https://doaj.org/article/1854a7e1960c44029afa2f6f6b8c9dcb