Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Philip G Haydon"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Neuronal activity undergoes significant changes during vigilance states, accompanied by an accommodation of energy demands. While the astrocyte-neuron lactate shuttle has shown that lactate is the primary energy substrate for sustaining neur
Externí odkaz:
https://doaj.org/article/60dff80641184a76b1e5174ab88bd923
Autor:
Kendall R Walker, Amit Modgil, David Albrecht, Selene Lomoio, Philip G Haydon, Stephen J Moss, Giuseppina Tesco
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155799 (2016)
Golgi-localized γ-ear-containing ARF binding protein 3 (GGA3) is a monomeric clathrin adaptor that has been shown to regulate the trafficking of the Beta-site APP-cleaving enzyme (BACE1), which is required for production of the Alzheimer's disease (
Externí odkaz:
https://doaj.org/article/f97a36937c584f06ae853a52e5cb0fbf
Autor:
Elsa N Bou Ghanem, Stacie Clark, Sara E Roggensack, Sally R McIver, Pilar Alcaide, Philip G Haydon, John M Leong
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005126 (2015)
An important determinant of disease following Streptococcus pneumoniae (pneumococcus) lung infection is pulmonary inflammation mediated by polymorphonuclear leukocytes (PMNs). We found that upon intratracheal challenge of mice, recruitment of PMNs in
Externí odkaz:
https://doaj.org/article/71c29e14cfd1463691a188f331f27d72
Autor:
Ulyana Lalo, Oleg Palygin, Seyed Rasooli-Nejad, Jemma Andrew, Philip G Haydon, Yuriy Pankratov
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001747 (2014)
Communication between neuronal and glial cells is important for many brain functions. Astrocytes can modulate synaptic strength via Ca(2+)-stimulated release of various gliotransmitters, including glutamate and ATP. A physiological role of ATP releas
Externí odkaz:
https://doaj.org/article/6a81a184e3a9445ea538f0b06cd80d22
Autor:
Robert Zorec, Alfonso Araque, Giorgio Carmignoto, Philip G Haydon, Alexei Verkhratsky, Vladimir Parpura
Publikováno v:
ASN Neuro, Vol 4 (2012)
Astroglial cells, due to their passive electrical properties, were long considered subservient to neurons and to merely provide the framework and metabolic support of the brain. Although astrocytes do play such structural and housekeeping roles in th
Externí odkaz:
https://doaj.org/article/09bcc7c167f241ef97b18bfe4cfa5cd0
Autor:
Moritz Armbruster, Saptarnab Naskar, Jacqueline P. Garcia, Mary Sommer, Elliot Kim, Yoav Adam, Philip G. Haydon, Edward S. Boyden, Adam E. Cohen, Chris G. Dulla
Publikováno v:
Nature Neuroscience. 25:607-616
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f34587797d45ca154da1b7a347143088
https://doi.org/10.1038/s41593-022-01049-x
https://doi.org/10.1038/s41593-022-01049-x
Autor:
Selene Lomoio, Ravi S. Pandey, Nicolas Rouleau, Beatrice Menicacci, WonHee Kim, William L. Cantley, Philip G. Haydon, David A. Bennett, Tracy L. Young-Pearse, Gregory W. Carter, David L. Kaplan, Giuseppina Tesco
BackgroundCurrent models to study Alzheimer’s disease (AD) include cell cultures and animal models. Human diseases, however, are often poorly reproduced in animal models. Developing techniques to differentiate human brain cells from induced pluripo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0df38cc1e2d0dcc039217844e20f208d
https://doi.org/10.1101/2022.07.21.501004
https://doi.org/10.1101/2022.07.21.501004
Autor:
Shefeeq M. Theparambil, Noemí Esteras, Philip G. Haydon, Patrick S. Hosford, Anna Hadjihambi, Anja G. Teschemacher, Alla Korsak, Mark F. Lythgoe, Egor A. Turovsky, Nephtali Marina, Alexander V. Gourine, Yichao Yu, Alice Braga
Publikováno v:
The Journal of Neuroscience
Teschemacher, A G 2020, ' Mechanosensory signalling in astrocytes ', Journal of Neuroscience . https://doi.org/10.1523/JNEUROSCI.1249-20.2020
Teschemacher, A G 2020, ' Mechanosensory signalling in astrocytes ', Journal of Neuroscience . https://doi.org/10.1523/JNEUROSCI.1249-20.2020
Mechanosensitivity is a well-known feature of astrocytes, however, its underlying mechanisms and functional significance remain unclear. There is evidence that astrocytes are acutely sensitive to decreases in cerebral perfusion pressure and may funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048d950691e1f343934537a3549a6335
http://europepmc.org/articles/PMC7724146
http://europepmc.org/articles/PMC7724146
Autor:
Michael M. Halassa, Marco Dal Maschio, Riccardo Beltramo, Philip G. Haydon, Fabio Benfenati, Tommaso Fellin
Publikováno v:
The Scientific World Journal, Vol 10, Pp 1634-1645 (2010)
Although astrocytes are increasingly recognized as important modulators of neuronal excitability and information transfer at the synapse, whether these cells regulate neuronal network activity has only recently started to be investigated. In this art
Externí odkaz:
https://doaj.org/article/ca6161589a9b43ae9ac98e954c7a05e9
Publikováno v:
The Scientific World Journal, Vol 7, Pp 89-97 (2007)
Though accumulating evidence shows that the metabotropic glutamate receptor 5 (mGluR5) mediates some of the actions of extracellular glutamate after cocaine use, the cellular events underlying this action are poorly understood. In this review, we wil
Externí odkaz:
https://doaj.org/article/08056a81e3d94752973b715d904db3c9