Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Philip F. Morgan"'
Autor:
John J. Savarese, Douglas L. Cohn, Vicente Samano, Paul L. Feldman, Michael McNulty, Timothy D. Spitzer, William B. Wastila, Robert A. Mook, Patel Sanjay Shashikant, Eric E. Boros, Mir Hashim, Matthew R. Belmont, Jan-Ake I. Schultz, Philip F. Morgan
Publikováno v:
Anesthesiology. 100:835-845
Background No replacement for succinylcholine is yet available. GW280430A (AV430A) is a representative of a new class of nondepolarizing neuromuscular blocking drugs called asymmetric mixed-onium chlorofumarates. It undergoes rapid degradation in pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c055781cf9210c04512d30a1722e8b1b
https://doi.org/10.1097/00000542-200404000-00013
https://doi.org/10.1097/00000542-200404000-00013
Publikováno v:
Life Sciences. 57:PL275-PL283
Binding of 3H-spiperone and 3H-raclopride to membranes of cells stably-transfected with a human dopamine D2 receptor clone was investigated, as was that of 3H-spiperone to those stably-transfected with a human D4 receptor clone. 3H-spiperone and 3H-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e6b795b2b3d5bbe8d7fede56a67446
https://doi.org/10.1016/0024-3205(95)02151-8
https://doi.org/10.1016/0024-3205(95)02151-8
Publikováno v:
British Journal of Pharmacology. 112:855-860
1. Administration of the irreversible antagonist, N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, (EEDQ, 2 mg kg-1, i.p.) to mice reduced binding of [3H]-RX 821002 (2-methoxy-idazoxan) to alpha 2-adrenoceptors in whole mouse brain by 75% 24 h later.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bac6063fe6a6878609d2c9e6a9803f
https://doi.org/10.1111/j.1476-5381.1994.tb13158.x
https://doi.org/10.1111/j.1476-5381.1994.tb13158.x
Publikováno v:
European Journal of Pharmacology. 257:311-314
The presence of both nitrobenzylthioinosine-sensitive and nitrobenzylthioinosine-insensitive dipyridamole binding sites in postmortem human ependymal tissue is reported. Displacement studies using 15 nM [ 3 H]dipyridamole revealed 50–60% of the sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ab21ebb55085c5d804fe7ef990a0b0
https://doi.org/10.1016/0014-2999(94)90145-7
https://doi.org/10.1016/0014-2999(94)90145-7
Autor:
Philip F. Morgan, Michael J. Durcan
Publikováno v:
European Journal of Pharmacology. 224:151-156
Caffeine and other methylxanthines induce a dose-dependent reduction in core body temperature in mice. These experiments investigated the effects of neurotransmitter and neuromodulator antagonists on caffeine-induced hypothermia. Pretreatment with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fec452b48a899a86090b4595e231c86
https://doi.org/10.1016/0014-2999(92)90799-a
https://doi.org/10.1016/0014-2999(92)90799-a
Autor:
Philip F. Morgan, Michael J. Durcan
Publikováno v:
European Journal of Pharmacology. 204:15-20
Caffeine induces a dose-dependent decrease in core body temperature in mice and the hypothermia induced by a 100 mg/kg dose of caffeine was seen to persist for greater than 160 min. Other alkylxanthines including theophylline, enprophylline, isbutylm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85aa682ba591cf23c0b663b74e308c6
https://doi.org/10.1016/0014-2999(91)90829-f
https://doi.org/10.1016/0014-2999(91)90829-f
Autor:
Philip F. Morgan, Michael J. Durcan
Publikováno v:
Psychological Medicine. 20:475-486
Psychological Medicine / Volume 20 / Issue 03 / August 1990, pp 475 486 DOI: 10.1017/S0033291700016986, Published online: 09 July 2009 Link to this article: http://journals.cambridge.org/abstract_S0033291700016986 How to cite this article: Michael J.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf181198556f788e9524206e652403d5
https://doi.org/10.1017/s0033291700016986
https://doi.org/10.1017/s0033291700016986
Autor:
Michael J. Durcan, Philip F. Morgan
Publikováno v:
Life Sciences. 47:1-8
The effect of adenosine agonist pretreatment on the seizure activity of caffeine was investigated in NIH Swiss mice. The seizure ED 50 of caffeine alone was determined to be 223 mg/kg and this was reduced to 68 mg/kg following pretreatment with 0.30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e4a8db2b74c608c06593575ce54d43
https://doi.org/10.1016/0024-3205(90)90559-a
https://doi.org/10.1016/0024-3205(90)90559-a
Autor:
Peter J. Gengo, Michael J. Durcan, Ching M. Wang, Anne V. Russell, Philip F. Morgan, Ronald M. Norton, Barrett R. Cooper, Stacy A. Jones-Humble, Richard F. Cox, Donald Lyerly, Flora L.M. Tang, Michael J. Watson
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 15(3)
11192U90 was submitted to receptor binding and monoamine uptake assays. It bound potently at serotonin 5-HT2, dopaminergic D2, serotonin 5-HT1A, and adrenergic alpha 1 and alpha 2 receptors. It also bound to dopaminergic D1, serotonin 5-HT3, serotoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6d87f697c4f774b5f233f30d8a0380
https://pubmed.ncbi.nlm.nih.gov/8873105
https://pubmed.ncbi.nlm.nih.gov/8873105
Publikováno v:
European journal of pharmacology. 225(3)
Brain structures activated during ethanol withdrawal have been mapped by visualizing c-fos mRNA expression. The regional distribution of c-fos mRNA in brain during ethanol withdrawal can be mimicked by acute injection of N-methyl-D-aspartic acid (NMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f838744413899bd5c4a7ecbfef28109
https://pubmed.ncbi.nlm.nih.gov/1355445
https://pubmed.ncbi.nlm.nih.gov/1355445