Zobrazeno 1 - 10
of 462
pro vyhledávání: '"Philip E. Bourne"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Our views of fold space implicitly rest upon many assumptions that impact how we analyze, interpret and understand protein structure, function and evolution. For instance, is there an optimal granularity in viewing protein structural similar
Externí odkaz:
https://doaj.org/article/fe54d7b4d16c4853bad85547b4dabd50
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Background Machine learning (ML) has a rich history in structural bioinformatics, and modern approaches, such as deep learning, are revolutionizing our knowledge of the subtle relationships between biomolecular sequence, structure, function,
Externí odkaz:
https://doaj.org/article/c6bda3fd57b8472a998f3e96bcf243a3
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0304632 (2024)
We propose a fold change transform that demonstrates a combination of visualization properties exhibited by log and linear plots of fold change. A fold change visualization should ideally exhibit: (1) readability, where fold change values are recover
Externí odkaz:
https://doaj.org/article/781c6356480045ccb4c640a83fb5a550
Autor:
Casey-Tyler Berezin, Luis U Aguilera, Sonja Billerbeck, Philip E Bourne, Douglas Densmore, Paul Freemont, Thomas E Gorochowski, Sarah I Hernandez, Nathan J Hillson, Connor R King, Michael Köpke, Shuyi Ma, Katie M Miller, Tae Seok Moon, Jason H Moore, Brian Munsky, Chris J Myers, Dequina A Nicholas, Samuel J Peccoud, Wen Zhou, Jean Peccoud
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011652 (2023)
Information is the cornerstone of research, from experimental (meta)data and computational processes to complex inventories of reagents and equipment. These 10 simple rules discuss best practices for leveraging laboratory information management syste
Externí odkaz:
https://doaj.org/article/b4c56a843deb47c5a60ffccf01b872d9
Autor:
Erin C McKiernan, Lorena Barba, Philip E Bourne, Caitlin Carter, Zach Chandler, Sayeed Choudhury, Stephen Jacobs, Daniel S Katz, Stefanie Lieggi, Beth Plale, Greg Tananbaum
Publikováno v:
PLoS Biology, Vol 21, Iss 7, p e3002204 (2023)
Research data is optimized when it can be freely accessed and reused. To maximize research equity, transparency, and reproducibility, policymakers should take concrete steps to ensure that research software is openly accessible and reusable.
Externí odkaz:
https://doaj.org/article/54729bc3d72f470b9284f5d73903facc
Autor:
Nathan C. Sheffield, Vivien R. Bonazzi, Philip E. Bourne, Tony Burdett, Timothy Clark, Robert L. Grossman, Ola Spjuth, Andrew D. Yates
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
The biomedical research community is investing heavily in biomedical cloud platforms. Cloud computing holds great promise for addressing challenges with big data and ensuring reproducibility in biology. However, despite their advantages, cloud platfo
Externí odkaz:
https://doaj.org/article/c867a7846612472da5e21de4897cece0
Autor:
Cameron Mura, Philip E. Bourne
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/49323bb4910b4a2db0a5bcb483e46b48
Autor:
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W Harding, Cameron Mura, Philip E Bourne, Lei Xie
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010851 (2023)
Systematically discovering protein-ligand interactions across the entire human and pathogen genomes is critical in chemical genomics, protein function prediction, drug discovery, and many other areas. However, more than 90% of gene families remain "d
Externí odkaz:
https://doaj.org/article/9ff4f70275c349c3ab853db6901603ee
Autor:
Davide Chicco, Philip E Bourne
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1010395 (2022)
Special sessions are important parts of scientific meetings and conferences: They gather together researchers and students interested in a specific topic and can strongly contribute to the success of the conference itself. Moreover, they can be the f
Externí odkaz:
https://doaj.org/article/d828f301c35b4cefb848b1d179f6cb1a
Autor:
Christine L. Borgman, Philip E. Bourne
Publikováno v:
Harvard Data Science Review (2022)
Externí odkaz:
https://doaj.org/article/35e45959b49e40288ee87468e412ac0b