Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Philip Doble"'
Autor:
Paul A. Adlard, Jacqui Parncutt, Varsha Lal, Simon James, Dominic Hare, Philip Doble, David I. Finkelstein, Ashley I. Bush
Publikováno v:
Neurobiology of Disease, Vol 81, Iss , Pp 196-202 (2015)
Zinc transporter-3 (ZnT3) protein is responsible for loading zinc into presynaptic vesicles and consequently controls the availability of zinc at the glutamatergic synapse. ZnT3 has been shown to decline with age and in Alzheimer's disease (AD) and i
Externí odkaz:
https://doaj.org/article/30d4752944f04d0bbdce8e3c4e00e11b
Autor:
Somin Lee, Ji-Eun Kim, Seong-Ho Hong, Ah-Young Lee, Eun-Jung Park, Hwi Won Seo, Chanhee Chae, Philip Doble, David Bishop, Myung-Haing Cho
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135582 (2015)
Inorganic phosphate (Pi) is required by all living organisms for the development of organs such as bone, muscle, brain, and lungs, regulating the expression of several critical genes as well as signal transduction. However, little is known about the
Externí odkaz:
https://doaj.org/article/a0aea08c7b054ce89c8a724046676cf6
Autor:
Claude Roux, Eduardo Geraldo de Campos, Philip Doble, Bruno Spinosa De Martinis, Lucas Blanes, Dayanne Mozaner Bordin, David P. Bishop
Publikováno v:
Journal of Analytical Toxicology. 46:991-998
Urine is initially collected from athletes to screen for the presence of illicit drugs. Sweat is an alternative sample matrix that provides advantages over urine including reduced opportunity for sample adulteration, longer detection-time window and
Publikováno v:
Analytical Chemistry. 93:10418-10423
Open-sourced software is a key component of the mass spectrometry imaging field, where transparency in data processing is vital. Imaging of trace elements and immunohistochemically labeled biomolecules in tissue sections is typically performed using
Autor:
Fred Fryer, Daniel D. Buchanan, Janet M. Hergt, Philip Doble, Jon Woodhead, Ashley I. Bush, Dominic J. Hare, Michael W. M. Jones, Bence Paul, Christophe Rosty, James B. Hilton, Robert W. Hutchinson, Kai Kysenius, David P. Bishop, Peter J. Crouch, Michelle M. Hill
Publikováno v:
Chemical Science
Tumours are abnormal growths of cells that reproduce by redirecting essential nutrients and resources from surrounding tissue. Changes to cell metabolism that trigger the growth of tumours are reflected in subtle differences between the chemical comp
Publikováno v:
The Analyst. 147(13)
This work introduces novel and universal workflows for the analysis of intact proteins by capillary electrophoresis and presents guidelines for the targeted selection of appropriate background electrolytes (BGEs) by consideration of the target protei
Autor:
Maximilian Horstmann, David P. Bishop, David Clases, Philip Doble, Uwe Karst, Raquel Gonzalez de Vega
Publikováno v:
Journal of Analytical Atomic Spectrometry. 36:767-775
Gd-based contrast agents (GBCAs) are frequently administered to patients for magnetic resonance imaging to enhance tissue contrasts. After examination, they are excreted and enter surface waters via local wastewater treatment plants' effluents where
Autor:
Philip Doble, Raquel Gonzalez de Vega, Alex Cameron, David P. Bishop, Tyren M. Dodgen, David Clases
Per- and polyfluoroalkyl substances (PFAS) represent a large group of synthetic organic compounds which exhibit unique properties and have been extensively used for consumer and industrial products, resulting in a widespread presence in the environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcbabe188dbbb0fc6d033d83d7f69f6
https://hdl.handle.net/10453/150392
https://hdl.handle.net/10453/150392
Publikováno v:
Chemical reviews. 121(19)
Elemental imaging gives insight into the fundamental chemical makeup of living organisms. Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements that define structure and function. Many disease states feature a dis
Autor:
Philip Doble, Mika T. Westerhausen, David P. Bishop, Jonathan Wanagat, Monique G. Mello, Prashina P. Singh
Publikováno v:
Anal Bioanal Chem
Analytical and bioanalytical chemistry, vol 413, iss 21
Analytical and bioanalytical chemistry, vol 413, iss 21
Immuno-mass spectrometry imaging (iMSI) uses laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) to determine the spatial expression of biomolecules in tissue sections following immunolabelling with antibodies conjugated to a meta