Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls

Autor: Bertrand Fontaine, Safa Saker-Delye, Malin Larsson, Kjell-Morten Myhr, Lena Guillot-Noel, Frauke Zipp, Graeme J. Stewart, Pouya Khankhanian, Bernhard Hemmer, Anders Hamsten, Per Hall, Finn Sellebjerg, Isabelle Cournu-Rebeix, Juliane Winkelmann, Nadia Barizzone, Bénédicte Dubois, Adrian J. Ivinson, David A. Hafler, An Goris, Lennox Din, Philip DeJager, Alastair Compston, Vincent Damotte, Stephen Sawcer, Janna Saarela, Giancarlo Comi, Stephen L. Hauser, Bruce V. Taylor, Maurizio Leone, Christina M. Lill, Anne Spurkland, Anu Kemppinen, David R. Booth, Keijo Koivisto, Maria Ban, Sandra D'Alfonso, Paola Naldi, Jorge R. Oksenberg, Fabio Macciardi, Helle Bach Søndergaard, Per Soelberg Sørensen, Jonathan L. Haines, Dorothea Buck, Tomas Olsson, Annette Bang Oturai, Andre Franke, Ingrid Kockum, F. Martinelli-Boneschi, Pentti J. Tienari, Vittorio Martinelli, Margaret A. Pericak-Vance, Jan Hillert, Federica Esposito, Laura Bergamaschi, Elisabeth Gulowsen Celius, Jim Stankovich, Roland Martin, Marco Salvetti, Pierre-Antoine Gourraud, Manuel Comabella, Mark Lathrop, Franco Perla, Chris Cotsapas, Hakon Hakonarson, Christiane Graetz, Nikolaos A. Patsopoulos, Mauri Reunanen, Michael Li, Paola Cavalla, Sergio E. Baranzini, Jacob L. McCauley, Franca Rosa Guerini, Irina Elovaara, Hanne F. Harbo

Publikováno v: American journal of human genetics. 92(6)

Multiple sclerosis (MS) is an inflammatory CNS disease with a substantial genetic component, originally mapped to only the human leukocyte antigen (HLA) region. In the last 5 years, a total of seven genome-wide association studies and one meta-analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafca886662571d638c6541e4f770ae7
https://pubmed.ncbi.nlm.nih.gov/23731539