Výsledky vyhledávání - "Philip D. Whanger"

Rumen Microorganisms Decrease Bioavailability of Inorganic Selenium Supplements

Autor: Philip D. Whanger, Charles T. Estill, Gerd Bobe, Jean A. Hall, T. Z. Davis, M. L. Galbraith, William R. Vorachek

Publikováno v: Biological Trace Element Research. 171:338-343

Despite the availability of selenium (Se)-enriched trace mineral supplements, we have observed low Se status in cattle and sheep offered traditional inorganic Se supplements. Reasons for this may include inadequate intake or low bioavailability of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401115d4339539ac41f8701f476703e7
https://doi.org/10.1007/s12011-015-0560-8

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Selenoprotein Gene Nomenclature

Autor: Ulrich Schweizer, Josef Köhrle, Michael T. Howard, Laurent Chavatte, Regina Brigelius-Flohé, Gustavo Salinas, Philip D. Whanger, Kaixun Huang, Fulvio Ursini, Matilde Maiorino, Raymond F. Burk, Marla J. Berry, Ick Young Kim, Dolph L. Hatfield, Miljan Simonović, Alexei V. Lobanov, Donna M. Driscoll, Margaret P. Rayman, Sharon Rozovsky, Alain Krol, Peter R. Hoffmann, Elias S.J. Arnér, Roger A. Sunde, Marcus Conrad, Fiona R. Green, Vadim N. Gladyshev, Byeong Jae Lee, Elspeth A. Bruford, Qiong Liu, Sergi Castellano, Ana Ferreiro, Xin Gen Lei, Bradley A. Carlson, Byung Cheon Lee, Gregory V. Kryukov, Alan M. Diamond, Paul R. Copeland, Yan Zhang, Edward E. Schmidt, Leopold Flohé, John E. Hesketh, Joseph Loscalzo, Marco Mariotti, Hwa-Young Kim, Roderic Guigó, Petra A. Tsuji, Lutz Schomburg, K. Sandeep Prabhu, Susan Tweedie, Diane E. Handy, Arne Holmgren, Alain Lescure, Robert J. Hondal

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2016, 291 (46), pp.24036-24040. ⟨10.1074/jbc.M116.756155⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (46), pp.24036-24040. ⟨10.1074/jbc.M116.756155⟩
J. Biol. Chem. 291, 24036-24040 (2016)

International audience; The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis. Selenoprotein enzymes with known functio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f2ae3803e0c38d55aa0270dea5ddf1
https://hal-riip.archives-ouvertes.fr/pasteur-01882353/document

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Selenoprotein W, Selenium and Glutathione Peroxidase in Rat and Sheep Brains and in Brain Cell Cultures

Autor: Neil E. Forsberg, Y. Sun, J. A. Butler, Philip D. Whanger

Publikováno v: Nutritional neuroscience. 2(4)

The effects of various selenium (Se) levels on seleno-protein W (SeW) content, Se concentration and glutathione peroxidase (GPX) activity in various parts of the brain from sheep and rats, and in glial and neuronal cells from rats were determined. Se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8d6eff0cb56cff7c8ae1cd689a2cd7
https://pubmed.ncbi.nlm.nih.gov/27415574

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Selenium and Mercury Interactions with Emphasis on Fish Tissue

Autor: Spencer A. Peterson, Nicholas V.C. Ralston, Wayne D. Mosher, Philip D. Whanger, J. E. Oldfield

Publikováno v: Environmental Bioindicators. 4:318-334

This review addresses the effects of mercury (Hg) in fish as it relates to the health of the fish themselves as well as potential risks of toxicity in wildlife and humans that consume fish. In particular, it addresses selenium (Se) as a bioindicator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9922891c1dea3d41ee51ed0e23272e60
https://doi.org/10.1080/15555270903358428

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Deletion analysis of the rodent selenoprotein W promoter

Autor: L.A. Hooven, William R. Vorachek, L.W. Ream, J.A. Butler, A.B. Bauman, Philip D. Whanger

Publikováno v: Journal of Inorganic Biochemistry. 99:2007-2012

To identify regulatory elements in the rat selenoprotein W (SeW) promoter, 2090, 1265, 741, and 404 base pair truncations of genomic DNA lying immediately upstream of the SeW coding sequence were cloned into a luciferase reporter vector (pGL3-Basic f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb051c7ef76ca29fddde49d12bea88b
https://doi.org/10.1016/j.jinorgbio.2005.06.035

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Metabolism of Subtoxic Level of Selenite by Double-Perfused Small Intestine in Rats

Autor: Jong-Bong Kim, Dong-Cheol Park, Woon-Gye Chung, S C Vendeland, Yong Heo, Hai-Won Chung, In-Sun Lee, Yeong-Chul Park, Philip D. Whanger, Jung-Ho Han

Publikováno v: Biological Trace Element Research. 98:143-158

Intestinal metabolism of the subtoxic level of selenite in rats was investigated using a double-perfusion system, which is an in situ, in vitro preparation in which the intestinal lumen and its vasculature are perfused simultaneously. The toxicity of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc24957f021651a383221fd5abc325b9
https://doi.org/10.1385/bter:98:2:143

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Selective production of rat mutant selenoprotein W with and without bound glutathione

Autor: Dean A. Malencik, Sonia R. Anderson, D.F. Barofsky, Elisabeth Barofsky, Philip D. Whanger, Andrew T. Bauman

Publikováno v: Biochemical and Biophysical Research Communications. 313:308-313

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) and electrospray ionization mass spectrometry (ESI MS) analysis of a 6x His-tagged recombinant form of rat mutant selenoprotein W (RMSW) reveals that aerobic growth conditions p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03436b4b729ba7006188d0457836e49
https://doi.org/10.1016/j.bbrc.2003.11.133

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Selenium and its relationship to cancer: an update

Autor: Philip D. Whanger

Publikováno v: British Journal of Nutrition. 91:11-28

Selenomethionine (Semet) is the major seleno-compound in cereal grains and enriched yeast whereas Se-methylselenocysteine (SeMCYS) is the major seleno-compound in Se-accumulator plants and some plants of economic importance such as garlic and broccol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58359c6055bd08e54ae46e909ab61cf
https://doi.org/10.1079/bjn20031015

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[Untitled]

Autor: Gu Qp, Walt Ream, Philip D. Whanger

Publikováno v: BioMetals. 15:411-420

The effects of selenium on selenoprotein W gene expression were examined in cultured L8 rat skeletal muscle cells. Selenoprotein W contains selenium as selenocysteine in the primary protein structure and levels of this selenoprotein are affected by s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dba1a18a110feec2143444a84437a9cf
https://doi.org/10.1023/a:1020241032336

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Baseline Selenium and Prostate Cancer Risk: Comments and Open Questions

Autor: Fred C. Madsen, Philip D. Whanger, Paul H. Frankel, Robert S. Parker

In the Selenium and Vitamin E Cancer Prevention Trial (SELECT) (1), neither 200 mcg/day of selenium (Se) from L-selenomethionine (SEM) nor 400 IU/day of all-racemic alpha-tocopheryl acetate (AT) provided benefit for the prevention of prostate cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a582a617f44ea9368592632c5689ce0a
https://europepmc.org/articles/PMC3982779/

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