Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Philip D. Townsend"'
Autor:
Michael J. Thomas, Wes Pawloski, George H. Lorimer, David Fushman, Victoria L. Linthwaite, Adrian P. Brown, Victor K. H. So, Martin J. Cann, Hamish B. Pegg, David R. W. Hodgson, Philip D. Townsend
Publikováno v:
Science Advances
Science advances, 2021, Vol.7(39), pp.eabi5507 [Peer Reviewed Journal]
Science advances, 2021, Vol.7(39), pp.eabi5507 [Peer Reviewed Journal]
Description
Altered ubiquitin conjugation is a mechanism by which mammalian cells can respond to fluctuating pCO2.
The identification of CO2-binding proteins is crucial to understanding CO2-regulated molecular processes. CO2 can form a reve
Altered ubiquitin conjugation is a mechanism by which mammalian cells can respond to fluctuating pCO2.
The identification of CO2-binding proteins is crucial to understanding CO2-regulated molecular processes. CO2 can form a reve
Autor:
Philip D Townsend, Britta Jungwirth, Florence Pojer, Michael Bußmann, Victoria A Money, Stewart T Cole, Alfred Pühler, Andreas Tauch, Michael Bott, Martin J Cann, Ehmke Pohl
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113265 (2014)
The cyclic AMP-dependent transcriptional regulator GlxR from Corynebacterium glutamicum is a member of the super-family of CRP/FNR (cyclic AMP receptor protein/fumarate and nitrate reduction regulator) transcriptional regulators that play central rol
Externí odkaz:
https://doaj.org/article/952552396c2b4bc7a4563b71c7006b89
Autor:
Thomas L Rodgers, Philip D Townsend, David Burnell, Matthew L Jones, Shane A Richards, Tom C B McLeish, Ehmke Pohl, Mark R Wilson, Martin J Cann
Publikováno v:
PLoS Biology, Vol 11, Iss 9, p e1001651 (2013)
Allostery is a fundamental process by which ligand binding to a protein alters its activity at a distinct site. There is growing evidence that allosteric cooperativity can be communicated by modulation of protein dynamics without conformational chang
Externí odkaz:
https://doaj.org/article/313384a500c94f30bfc7ec0bdb187ff3
Autor:
Octavina C.A. Sukarta, Wladimir I. L. Tameling, Jaap Bakker, Jan Roosien, Olga Drawska, Aska Goverse, Martin J. Cann, Andrei-Jose Petrescu, Jan Willem Borst, Laurentiu N. Spiridon, Arjen Schots, Rikus Pomp, Geert Smant, Philip D. Townsend, E.J. Slootweg, Matthieu H. A. J. Joosten, Eliza C. Martin
Publikováno v:
Plant Physiology, 178(3), 1310-1331
Plant physiology, 2018, Vol.178(3), pp.1310-1331 [Peer Reviewed Journal]
Plant Physiology 178 (2018) 3
Plant physiology, 2018, Vol.178(3), pp.1310-1331 [Peer Reviewed Journal]
Plant Physiology 178 (2018) 3
The intracellular immune receptor Rx1 of potato (Solanum tuberosum), which confers effector-triggered immunity to Potato virus X, consists of a central nucleotide-binding domain (NB-ARC) flanked by a carboxyl-terminal leucine-rich repeat (LRR) domain
Autor:
Octavina C.A. Sukarta, Frank L. W. Takken, Aska Goverse, Christopher H. Dixon, Alexander Llewelyn, Philip D. Townsend, E.J. Slootweg, Martin J. Cann, Lars-Olof Pålsson
Publikováno v:
Plant Communications, 1(4)
Plant communications, 2020, Vol.1(4), pp.100086 [Peer Reviewed Journal]
Plant Communications 1 (2020) 4
Plant communications, 1(4). Cell Press
Plant Communications
Plant communications, 2020, Vol.1(4), pp.100086 [Peer Reviewed Journal]
Plant Communications 1 (2020) 4
Plant communications, 1(4). Cell Press
Plant Communications
Plant NLR proteins enable the immune system to recognize and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming. Some NLRs have been shown to act in the nucleus and interact with transcription facto
Autor:
Gary J. Sharples, Octavina C.A. Sukarta, Ally Yang, Christopher H. Dixon, Philip D. Townsend, Aska Goverse, Timothy P. Hughes, Lars-Olof Pålsson, Martin J. Cann, Frank L. W. Takken, E.J. Slootweg
Publikováno v:
Journal of biological chemistry, 2018, Vol.293(9), pp.3218-3233 [Peer Reviewed Journal]
The Journal of Biological Chemistry, 293(9), 3218-3233. American Society for Biochemistry and Molecular Biology Inc.
The Journal of Biological Chemistry
Journal of Biological Chemistry 293 (2018) 9
Journal of Biological Chemistry, 293(9), 3218-3233
The Journal of Biological Chemistry, 293(9), 3218-3233. American Society for Biochemistry and Molecular Biology Inc.
The Journal of Biological Chemistry
Journal of Biological Chemistry 293 (2018) 9
Journal of Biological Chemistry, 293(9), 3218-3233
Plant nucleotide-binding leucine–rich repeat (NLR) proteins enable the immune system to recognize and respond to pathogen attack. An early consequence of immune activation is transcriptional reprogramming, and some NLRs have been shown to act in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22b31780532545d2f19218e4514e04f
https://doi.org/10.1074/jbc.RA117.000485
https://doi.org/10.1074/jbc.RA117.000485
Autor:
Paul D. Facey, Ricardo Del Sol, Paul Dyson, Philip D. Townsend, D. Hugh Jones, Ehmke Pohl, Matthew D. Hitchings
Publikováno v:
Cellular and Molecular Life Sciences. 71:4911-4926
Dps proteins are members of an extensive family of proteins that oxidise and deposit iron in the form of ferric oxide, and are also able to bind DNA. Ferroxidation centres are formed at the interface of anti-parallel dimers, which further assemble in
Autor:
Kenneth C. Hess, Stepan Fenyk, Martin J. Cann, Philip D. Townsend, Michael A. Gray, Phillip M. Holliday, David R. W. Hodgson
Publikováno v:
The Journal of Biological Chemistry
Journal of biological chemistry, 2009, Vol.284(2), pp.784-791 [Peer Reviewed Journal]
Journal of biological chemistry, 2009, Vol.284(2), pp.784-791 [Peer Reviewed Journal]
Carbon dioxide is fundamental to the physiology of all organisms. There is considerable interest in the precise molecular mechanisms that organisms use to directly sense CO(2). Here we demonstrate that a mammalian recombinant G-protein-activated aden
Autor:
Philip D, Townsend, Thomas L, Rodgers, Laura C, Glover, Heidi J, Korhonen, Shane A, Richards, Lucy J, Colwell, Ehmke, Pohl, Mark R, Wilson, David R W, Hodgson, Tom C B, McLeish, Martin J, Cann
Publikováno v:
The Journal of Biological Chemistry
Background: Protein allostery can be communicated purely through altered entropy. Results: Altered cAMP binding strength in CAP results in changes to entropy-driven allostery. Conclusion: The requirement to maintain allostery constrains evolution of
Autor:
Martin J. Cann, Philip D. Townsend, Thomas L. Rodgers, Ehmke Pohl, Mark R. Wilson, Tom McLeish
Publikováno v:
Physical Biology of Proteins and Peptides ISBN: 9783319216867
We review the idea that allosteric interactions can be transmitted not by structural switching but by the more subtle route of modulation of the amplitude of thermally-activated global dynamical modes in allosteric proteins. The effect is naturally a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a47328a4ecb33f7fd9df134a512e89d
https://doi.org/10.1007/978-3-319-21687-4_8
https://doi.org/10.1007/978-3-319-21687-4_8