Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Philip D. Jeffrey"'
Publikováno v:
ACS Central Science, Vol 8, Iss 3, Pp 340-350 (2022)
Externí odkaz:
https://doaj.org/article/609ac71d142e4f7383bbc03c94dc7519
Autor:
Felix Adusei-Danso, Faisal Tarique Khaja, Micaela DeSantis, Philip D. Jeffrey, Eugenie Dubnau, Borries Demeler, Matthew B. Neiditch, David Dubnau
Publikováno v:
mBio, Vol 10, Iss 5 (2019)
ABSTRACT In Bacillus subtilis, the RicA (YmcA), RicF (YlbF), and RicT (YaaT) proteins accelerate the phosphorylation of the transcription factor Spo0A, contributing to genetic competence, sporulation, and biofilm formation, and are also essential for
Externí odkaz:
https://doaj.org/article/89f19326c9aa4620b076c13dda6e7ddb
Autor:
Travis J Eisemann, Frederick Allen, Kelly Lau, Gregory R Shimamura, Philip D Jeffrey, Frederick M Hughson
Publikováno v:
eLife, Vol 9 (2020)
Fusion of intracellular trafficking vesicles is mediated by the assembly of SNARE proteins into membrane-bridging complexes. SNARE-mediated membrane fusion requires Sec1/Munc18-family (SM) proteins, SNARE chaperones that can function as templates to
Externí odkaz:
https://doaj.org/article/e9c0b28703b047e99878b8ee5f275565
Autor:
Kevin A. DAmico, Abigail E. Stanton, Jaden D. Shirkey, Sophie M. Travis, Philip D. Jeffrey, Frederick M. Hughson
Most membrane fusion reactions in eukaryotic cells are mediated by membrane tethering complexes (MTCs) and SNARE proteins. MTCs are much larger than SNAREs and are thought to mediate the initial attachment of two membranes. Complementary SNAREs then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f19521c88d164bd1056c1a8de0c8ffa
https://doi.org/10.1101/2023.01.30.526244
https://doi.org/10.1101/2023.01.30.526244
Autor:
Nathan Coutard, Jonathan M. Goldberg, Henry U. Valle, Yuan Cao, Xiaofan Jia, Philip D. Jeffrey, T. Brent Gunnoe, John T. Groves
Publikováno v:
Inorganic Chemistry. 61:759-766
Photodriven oxidations of alkanes in trifluoroacetic acid using commercial and synthesized Fe(III) sources as catalyst precursors and dioxygen (O
Autor:
Liping Zhao, Alexei Korennykh, Guojun Wu, Abhishek Biswas, Mohamed S. Donia, Michael A. Estrella, Philip D. Jeffrey, Jared N. Balaich
Publikováno v:
Nature
The human microbiome encodes a large repertoire of biochemical enzymes and pathways, most of which remain uncharacterized. Here, using a metagenomics-based search strategy, we discovered that bacterial members of the human gut and oral microbiome enc
Autor:
Rong Hu, Umar Farook Shahul Hameed, Xiang Sun, Balakrishnan Shenbaga Moorthy, Wen Zhang, Philip D. Jeffrey, Li Zhou, Xin Ma, Fangjin Chen, Jianfeng Pei, Pankaj K. Giri, Yonggao Mou, Kunchithapadam Swaminathan, Ping Yuan
Publikováno v:
Cell Proliferation. 56
Elimination of brain tumour initiating cells (BTICs) is important for the good prognosis of malignant brain tumour treatment. To develop a novel strategy targeting BTICs, we studied NR2E1(TLX) involved self-renewal mechanism of BTICs and explored the
Autor:
Isabelle R, Taylor, Philip D, Jeffrey, Dina A, Moustafa, Joanna B, Goldberg, Bonnie L, Bassler
Publikováno v:
Biochemistry. 61(17)
The opportunistic pathogen
Publikováno v:
Proceedings of the National Academy of Sciences. 119
All kingdoms of life produce essential nicotinamide dinucleotide NADP(H) using NAD kinases (NADKs). A panel of published NADK structures from bacteria, eukaryotic cytosol, and yeast mitochondria revealed similar tetrameric enzymes. Here, we present t
Autor:
Brad R. Henke, Bonnie L. Bassler, Isabelle R. Taylor, Chari D. Smith, Philip D. Jeffrey, Jon E. Paczkowski
Publikováno v:
ACS Chemical Biology. 16:740-752
Pseudomonas aeruginosa is an opportunistic human pathogen that causes fatal infections. There exists an urgent need for new antimicrobial agents to combat P. aeruginosa. We conducted a screen for molecules that bind the virulence-controlling protein