Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Philip D. Butcher"'
Autor:
Paula J. Gomez-Gonzalez, Nuria Andreu, Jody E. Phelan, Paola Florez de Sessions, Judith R. Glynn, Amelia C. Crampin, Susana Campino, Philip D. Butcher, Martin L. Hibberd, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact
Externí odkaz:
https://doaj.org/article/81df4f864ec84de0b601906353fb8804
Autor:
Adam A. Witney, Anna L. E. Bateson, Amina Jindani, Patrick P. J. Phillips, David Coleman, Neil G. Stoker, Philip D. Butcher, Timothy D. McHugh, RIFAQUIN Study Team
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including regimens with high-dose rifapentine with moxifloxacin. Here, the application of whole-genome sequencing (WGS) is evaluated within RIFAQUIN for identifying
Externí odkaz:
https://doaj.org/article/8b485d5bfae443b0bac7ebba395890d0
Autor:
Elena G. Salina, Simon J. Waddell, Nadine Hoffmann, Ida Rosenkrands, Philip D. Butcher, Arseny S. Kaprelyants
Publikováno v:
Open Biology, Vol 4, Iss 10 (2014)
Dormancy in non-sporulating bacteria is an interesting and underexplored phenomenon with significant medical implications. In particular, latent tuberculosis may result from the maintenance of Mycobacterium tuberculosis bacilli in non-replicating sta
Externí odkaz:
https://doaj.org/article/00f260c93d6e4a4db17e1dde218b7a3c
Autor:
Paul T. Heath, Philip D. Butcher, Clarissa Oeser, Marcus Pond, Philipp Henneke, Tim Planche, Ken Laing, Alison Bedford Russell, Kathryn A. Harris
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226817 (2020)
PLoS ONE
PLoS ONE
Background A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e019a849cbe22f3f2728bf1bb4e111
https://openaccess.sgul.ac.uk/id/eprint/111608/1/Oeser_EOS_PCR_PLoSOne2020.pdf
https://openaccess.sgul.ac.uk/id/eprint/111608/1/Oeser_EOS_PCR_PLoSOne2020.pdf
Autor:
Philip D. Butcher, Jody Phelan, Judith R. Glynn, Martin L. Hibberd, Taane G. Clark, Amelia C. Crampin, Paula J. Gomez-Gonzalez, Nuria Andreu, Susana Campino, Paola Florez de Sessions
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact on transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa27d3664237e2d3e762affb515f92
https://openaccess.sgul.ac.uk/id/eprint/110782/1/s41598-019-41692-2.pdf
https://openaccess.sgul.ac.uk/id/eprint/110782/1/s41598-019-41692-2.pdf
Autor:
Jason Hinds, Philip D. Butcher, Derek C. Macallan, Peter Riley, Thomas S. Harrison, Angela Houston, Stephania Vergnano, Amber Arnold, Catherine Cosgrove, Adam A. Witney, Katherine A. Gould, Anita Roche
Publikováno v:
Journal of Infection. 73:210-218
Summary Objectives We describe the first published cluster of extensively drug resistant Tuberculosis (XDR-TB) in the UK and show how early whole genome sequencing (WGS) of Mtb can assist in case management and contact investigations. Methods We desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b626cb1578f1b46e4443060687f907d
https://doi.org/10.1016/j.jinf.2016.04.037
https://doi.org/10.1016/j.jinf.2016.04.037
Autor:
Marcus Pond, Syed Tariq Sadiq, Margarita Ajayi, Achyuta V Nori, Ken Laing, Sheel Patel, Phillip Hay, Philip D. Butcher, Andrew Copas
Publikováno v:
Sexually Transmitted Infections
OBJECTIVES: Gram-stained urethral smear (GSUS), the standard point-of-care test for non-gonococcal urethritis (NGU) is operator dependent and poorly specific. The performance of rapid automated urine flow cytometry (AUFC) of first void urine (FVU) wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0575b3251765361c361544d41fd80ea
http://europepmc.org/articles/PMC4413809
http://europepmc.org/articles/PMC4413809
Autor:
Josef Wagner, Marcus Pond, Julian Parkhill, Tariq Sadiq, Philip D. Butcher, Achyuta V Nori, Ken Laing
Publikováno v:
Systems Biology and Novel Technologies For Molecular Analysis and Diagnosis.
Introduction Applying bacterial 16S rRNA profiling we investigated whether species in first void urine (FVU) differed between men presenting with urethritis symptoms with and without urethral inflammation. Methods 443 patients prospectively attending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47cda6c66f605475b41c85267cc4d06a
https://doi.org/10.1136/sextrans-2017-053264.146
https://doi.org/10.1136/sextrans-2017-053264.146
Autor:
Thomas S. Harrison, Amber Arnold, Graham S Cooke, Marc Lipman, Martin Dedicoat, Onn Min Kon, Angela Loyse, Irina Chis Ster, Philip D. Butcher
OBJECTIVES: Detailed information regarding treatment practices and outcomes of MDR-TB treatment in the UK is required as a baseline for care improvements. METHODS: 100 consecutive cases between 2008 and 2014 were reviewed retrospectively at 4 MDR-TB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84f897aed9d922b0a509b4d0e437fc3
http://hdl.handle.net/10044/1/49074
http://hdl.handle.net/10044/1/49074
Autor:
Simon J. Waddell, Katharina Ronacher, Philip D. Butcher, Delmiro Fernandez-Reyes, Iitu Kuittinen, Gerhard Walzl, Dimitrios Evangelopoulos, Paul D. van Helden, Juho Rousu, Anna Cichonska, Isobella Honeyborne, Timothy D. McHugh, Stephen H. Gillespie
Publikováno v:
BMC Medicine
SJW, PDB, SGH and TMcH are part of the PreDiCT-TB consortium (http://www.predict-tb.eu) which is funded from the Innovative Medicines Initiative Joint Undertaking (http://www.imi.europa.eu) under grant agreement No 115337, resour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0d9a95b714fdcb9a1054a64809df40
https://hdl.handle.net/10023/8682
https://hdl.handle.net/10023/8682