Výsledky vyhledávání - "Philip D Allen"

Akademický článek

Cardio-Respiratory synchronized bSSFP MRI for high throughput in vivo lung tumour quantification.

Autor: Ana L Gomes, Paul Kinchesh, Stuart Gilchrist, Philip D Allen, Luiza Madia Lourenço, Anderson J Ryan, Sean C Smart

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0212172 (2019)

The identification and measurement of tumours is a key requirement in the study of tumour development in mouse models of human cancer. Disease burden in autochthonous tumours, such as those arising in the lung, can be seen with non-invasive imaging,

Externí odkaz: https://doaj.org/article/0cdd933fe5b64c7eafda8fdc20e58782

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Akademický článek

An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.

Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0176693 (2017)

Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was to develop a robust and accurate method of MRI-guided radiotherapy (MR-IGRT) delivery to ab

Externí odkaz: https://doaj.org/article/ae518cca3a5a4ee6a6bf6b30edf910b8

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Akademický článek

An MRI-Compatible High Frequency AC Resistive Heating System for Homeothermic Maintenance in Small Animals.

Autor: Stuart Gilchrist, Ana L Gomes, Paul Kinchesh, Veerle Kersemans, Philip D Allen, Sean C Smart

Publikováno v: PLoS ONE, Vol 11, Iss 11, p e0164920 (2016)

To develop an MRI-compatible resistive heater, using high frequency alternating current (AC), for temperature maintenance of anaesthetised animals.An MRI-compatible resistive electrical heater was formed from narrow gauge wire connected to a high fre

Externí odkaz: https://doaj.org/article/3aa91842a5ff4cd783a6041d110222cd

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Akademický článek

Improving In Vivo High-Resolution CT Imaging of the Tumour Vasculature in Xenograft Mouse Models through Reduction of Motion and Bone-Streak Artefacts.

Autor: Veerle Kersemans, Pavitra Kannan, John S Beech, Russell Bates, Benjamin Irving, Stuart Gilchrist, Philip D Allen, James Thompson, Paul Kinchesh, Christophe Casteleyn, Julia Schnabel, Mike Partridge, Ruth J Muschel, Sean C Smart

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128537 (2015)

Preclinical in vivo CT is commonly used to visualise vessels at a macroscopic scale. However, it is prone to many artefacts which can degrade the quality of CT images significantly. Although some artefacts can be partially corrected for during image

Externí odkaz: https://doaj.org/article/ed6f36bc39f44202a4c525d14f8c532a

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Akademický článek

Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation.

Autor: Veerle Kersemans, Bart Cornelissen, Rebekka Hueting, Matthew Tredwell, Kamila Hussien, Philip D Allen, Nadia Falzone, Sally A Hill, Jonathan R Dilworth, Veronique Gouverneur, Ruth J Muschel, Sean C Smart

Publikováno v: PLoS ONE, Vol 6, Iss 11, p e25911 (2011)

Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly alter experimental outcome. This study reports on the effects of both anaesthetic and carrier gas upon

Externí odkaz: https://doaj.org/article/d94b7216c0104b6580d8720de7aaccac

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Data from Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases

Purpose: Tumor vessels influence the growth and response of tumors to therapy. Imaging vascular changes in vivo using dynamic contrast-enhanced MRI (DCE-MRI) has shown potential to guide clinical decision making for treatment. However, quantitative M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8bf5abfae121c63556b55f9b40579c
https://doi.org/10.1158/1078-0432.c.6527586

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Supplementary Information from Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases

Supplementary methods and data. Supplementary Table 1. Equations of chosen models fit using ordinary least squares regression with the best Bayesian Information Criterion for iAUC90, Ktrans, and BATfrac in untreated preclinical tumors (cohort 1). Goo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57976c059b7a53d0abb5e6c056d2f328
https://doi.org/10.1158/1078-0432.22470495.v1

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A System-Agnostic, Adaptable and Extensible Animal Support Cradle System for Cardio-Respiratory-Synchronised, and Other, Multi-Modal Imaging of Small Animals

Autor: Sean Smart, Veerle Kersemans, Stuart Gilchrist, John Prentice, Martin Tweedie, Paul Kinchesh, Jamie H. Warner, Philip D. Allen, Sheena Wallington

Publikováno v: Tomography; Volume 7; Issue 1; Pages: 39-54
Tomography
Volume 7
Issue 1
Pages 4-54
Tomography, Vol 7, Iss 4, Pp 39-54 (2021)

Standardisation of animal handling procedures for a wide range of preclinical imaging scanners will improve imaging performance and reproducibility of scientific data. Whilst there has been significant effort in defining how well scanners should oper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f3a92e5225bdce9ef449ec8907a5ba
https://doi.org/10.3390/tomography7010004

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