Výsledky vyhledávání - "Philip D, Poorvu"

Akademický článek

Estrogen levels in young women with hormone receptor-positive breast cancer on ovarian function suppression therapy

Autor: Megan E. Tesch, Yue Zheng, Shoshana M. Rosenberg, Philip D. Poorvu, Kathryn J. Ruddy, Rulla Tamimi, Lidia Schapira, Jeffrey Peppercorn, Virginia Borges, Steven E. Come, Craig Snow, Shalender Bhasin, Ann H. Partridge

Publikováno v: npj Breast Cancer, Vol 10, Iss 1, Pp 1-8 (2024)

Abstract Ovarian function suppression (OFS) benefits young women with hormone receptor (HR)-positive breast cancer but they are at risk for ovarian function breakthrough. We assessed endocrine effects of gonadotropin-releasing hormone agonist (GnRHa)

Externí odkaz: https://doaj.org/article/f3ae8ab8377e4157997d9785ff9388a8

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Akademický článek

Helping ourselves, helping others: the Young Women’s Breast Cancer Study (YWS) – a multisite prospective cohort study to advance the understanding of breast cancer diagnosed in women aged 40 years and younger

Autor: Lidia Schapira, Yue Zheng, Laura Collins, Ann H Partridge, Jeffrey Peppercorn, Virginia F Borges, Rulla M Tamimi, Gregory J Kirkner, Eric P Winer, Kathryn Ruddy, Shoshana M Rosenberg, Philip D Poorvu, Craig Snow, Meghan E Meyer, Steven Come, Ellen Warner, Shari Gelber

Publikováno v: BMJ Open, Vol 14, Iss 6 (2024)

Purpose Compared with older women diagnosed with breast cancer, younger women are more likely to die of breast cancer and more likely to suffer psychosocially in both the short-term and long term. The Young Women’s Breast Cancer Study (YWS) is a mu

Externí odkaz: https://doaj.org/article/f524706438004f91987fdbc6e69b0465

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Akademický článek

A prospective trial of treatment de-escalation following neoadjuvant paclitaxel/trastuzumab/pertuzumab in HER2-positive breast cancer

Publikováno v: npj Breast Cancer, Vol 8, Iss 1, Pp 1-7 (2022)

Abstract De-escalating adjuvant therapy following pathologic complete response (pCR) to an abbreviated neoadjuvant regimen in human epidermal growth factor receptor 2-positive (HER2+) breast cancer is the focus of international research efforts. Howe

Externí odkaz: https://doaj.org/article/d0192c11039b44b882550c174a83425c

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Akademický článek

Autor: Philip D. Poorvu, Jiani Hu, Yue Zheng, Shari I. Gelber, Kathryn J. Ruddy, Rulla M. Tamimi, Jeffrey M. Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Ellen Warner, Matteo Lambertini, Shoshana M. Rosenberg, Ann H. Partridge

Publikováno v: npj Breast Cancer, Vol 7, Iss 1, Pp 1-7 (2021)

Abstract Young women with breast cancer experience unique treatment and survivorship issues centering on treatment-related amenorrhea (TRA), including fertility preservation and management of ovarian function as endocrine therapy. The Young Women’s

Externí odkaz: https://doaj.org/article/592ffffed0fa43e097016755a05439e6

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Adjuvant Olaparib for Germline BRCA Carriers With HER2-Negative Early Breast Cancer: Evidence and Controversies

Autor: Stefania Morganti, Brittany L Bychkovsky, Philip D Poorvu, Ana C Garrido-Castro, Anna Weiss, Caroline C Block, Ann H Partridge, Giuseppe Curigliano, Nadine M Tung, Nancy U Lin, Judy E Garber, Sara M Tolaney, Filipa Lynce

Publikováno v: The Oncologist.

In the OlympiA study, 1 year of adjuvant olaparib significantly extended invasive disease-free survival and overall survival. The benefit was consistent across subgroups, and this regimen is now recommended after chemotherapy for germline BRCA1/2 mut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4f5eb6d43e5fe9a30df121ea1999222
https://doi.org/10.1093/oncolo/oyad123

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Somatic and germline genomic alterations in very young women with breast cancer

Autor: Adrienne G. Waks, Dewey Kim, Esha Jain, Craig Snow, Gregory J. Kirkner, Shoshana M. Rosenberg, Coyin Oh, Philip D. Poorvu, Kathryn J. Ruddy, Rulla M. Tamimi, Jeffrey Peppercorn, Lidia Schapira, Virginia F. Borges, Steven E. Come, Elena F. Brachtel, Ellen Warner, Laura C. Collins, Ann H. Partridge, Nikhil Wagle

Publikováno v: Clinical Cancer Research, 28(11), 2339-2348. American Association for Cancer Research Inc.

Purpose:Young age at breast cancer diagnosis correlates with unfavorable clinicopathologic features and worse outcomes compared with older women. Understanding biological differences between breast tumors in young versus older women may lead to bette

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f910a028d8e11db09bda161f50ae6d
https://doi.org/10.1158/1078-0432.ccr-21-2572

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