Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Philip D, Butcher"'
Autor:
Paula J. Gomez-Gonzalez, Nuria Andreu, Jody E. Phelan, Paola Florez de Sessions, Judith R. Glynn, Amelia C. Crampin, Susana Campino, Philip D. Butcher, Martin L. Hibberd, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact
Externí odkaz:
https://doaj.org/article/81df4f864ec84de0b601906353fb8804
Autor:
Adam A. Witney, Anna L. E. Bateson, Amina Jindani, Patrick P. J. Phillips, David Coleman, Neil G. Stoker, Philip D. Butcher, Timothy D. McHugh, RIFAQUIN Study Team
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including regimens with high-dose rifapentine with moxifloxacin. Here, the application of whole-genome sequencing (WGS) is evaluated within RIFAQUIN for identifying
Externí odkaz:
https://doaj.org/article/8b485d5bfae443b0bac7ebba395890d0
Autor:
Elena G. Salina, Simon J. Waddell, Nadine Hoffmann, Ida Rosenkrands, Philip D. Butcher, Arseny S. Kaprelyants
Publikováno v:
Open Biology, Vol 4, Iss 10 (2014)
Dormancy in non-sporulating bacteria is an interesting and underexplored phenomenon with significant medical implications. In particular, latent tuberculosis may result from the maintenance of Mycobacterium tuberculosis bacilli in non-replicating sta
Externí odkaz:
https://doaj.org/article/00f260c93d6e4a4db17e1dde218b7a3c
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88149 (2014)
Tuberculosis (TB) remains a major global public health problem. The only vaccine, BCG, gives variable protection, especially in adults, so several new vaccines are in clinical trials. There are no correlates of protective immunity to TB; therefore va
Externí odkaz:
https://doaj.org/article/28a50452a964413ca13a01becd5b6ace
Autor:
Paul T. Heath, Philip D. Butcher, Clarissa Oeser, Marcus Pond, Philipp Henneke, Tim Planche, Ken Laing, Alison Bedford Russell, Kathryn A. Harris
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226817 (2020)
PLoS ONE
PLoS ONE
Background A large proportion of neonates are treated for presumed bacterial sepsis with broad spectrum antibiotics even though their blood cultures subsequently show no growth. This study aimed to investigate PCR-based methods to identify pathogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e019a849cbe22f3f2728bf1bb4e111
https://openaccess.sgul.ac.uk/id/eprint/111608/1/Oeser_EOS_PCR_PLoSOne2020.pdf
https://openaccess.sgul.ac.uk/id/eprint/111608/1/Oeser_EOS_PCR_PLoSOne2020.pdf
Autor:
Alice H Li, Simon J Waddell, Jason Hinds, Chad A Malloff, Manjeet Bains, Robert E Hancock, Wan L Lam, Philip D Butcher, Richard W Stokes
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11066 (2010)
H37Rv and H37Ra are well-described laboratory strains of Mycobacterium tuberculosis derived from the same parental strain, H37, that show dramatically different pathogenic phenotypes.In this study, the transcriptomes of the two strains during axenic
Externí odkaz:
https://doaj.org/article/780a64bf82654027a3fca32b503b54a2
Autor:
Natalie J Garton, Simon J Waddell, Anna L Sherratt, Su-Min Lee, Rebecca J Smith, Claire Senner, Jason Hinds, Kumar Rajakumar, Richard A Adegbola, Gurdyal S Besra, Philip D Butcher, Michael R Barer
Publikováno v:
PLoS Medicine, Vol 5, Iss 4, p e75 (2008)
BackgroundTuberculous sputum provides a sample of bacilli that must be eliminated by chemotherapy and that may go on to transmit infection. A preliminary observation that Mycobacterium tuberculosis cells contain triacylglycerol lipid bodies in sputum
Externí odkaz:
https://doaj.org/article/c43881be510240439f751f7dc9ae3b6d
Autor:
Ruth Stavrum, Håvard Valvatne, Trond H Bø, Inge Jonassen, Jason Hinds, Philip D Butcher, Harleen M S Grewal
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1973 (2008)
The Beijing family of Mycobacterium tuberculosis is dominant in countries in East Asia. Genomic polymorphisms are a source of diversity within the M. tuberculosis genome and may account for the variation of virulence among M. tuberculosis isolates. T
Externí odkaz:
https://doaj.org/article/1b460c5b6d784d1b81be76b1e9921b06
Autor:
Ludovic Tailleux, Simon J Waddell, Mattia Pelizzola, Alessandra Mortellaro, Michael Withers, Antoine Tanne, Paola Ricciardi Castagnoli, Brigitte Gicquel, Neil G Stoker, Philip D Butcher, Maria Foti, Olivier Neyrolles
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1403 (2008)
Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium tuberculosis,
Externí odkaz:
https://doaj.org/article/65e48e15cfcc4b5bad153688fefb88e7
Autor:
Philip D. Butcher, Jody Phelan, Judith R. Glynn, Martin L. Hibberd, Taane G. Clark, Amelia C. Crampin, Paula J. Gomez-Gonzalez, Nuria Andreu, Susana Campino, Paola Florez de Sessions
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact on transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa27d3664237e2d3e762affb515f92
https://openaccess.sgul.ac.uk/id/eprint/110782/1/s41598-019-41692-2.pdf
https://openaccess.sgul.ac.uk/id/eprint/110782/1/s41598-019-41692-2.pdf