Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Philip Chowienczyk"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Several studies suggest that central (aortic) blood pressure (cBP) is a better marker of cardiovascular disease risk than peripheral blood pressure (pBP). The morphology of the pBP wave, usually assessed non-invasively in the arm, differs significant
Externí odkaz:
https://doaj.org/article/8c7a96271cd44d58b88e4bc9d856b300
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0245026 (2021)
One of the European gold standard measurement of vascular ageing, a risk factor for cardiovascular disease, is the carotid-femoral pulse wave velocity (cfPWV), which requires an experienced operator to measure pulse waves at two sites. In this work,
Externí odkaz:
https://doaj.org/article/8b0c22e681634ddfab69f8477163370c
Autor:
Ludovica Bognoni, Marina Cecelja, Tarique Hussain, Gerald Greil, Tim Spector, Philip Chowienczyk, J. Kennedy Cruickshank
Publikováno v:
Artery Research, Vol 26, Iss 4 (2020)
Background: Carotid-femoral Pulse Wave Velocity (cfPWV) is the gold-standard measure of arterial stiffness. Accuracy of non-invasive cfPWV as meters per second is impeded by surface estimates of aortic length. Our aim was to compare cfPWV measured us
Externí odkaz:
https://doaj.org/article/6cc92d8e89c643788f664fa636849fdc
Autor:
Kevin O'Gallagher, Husain Shabeeh, Shahzad Munir, Ali Roomi, Benyu Jiang, Antoine Guilcher, Sally Brett, Philip Chowienczyk
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 16 (2020)
Background Basal release of nitric oxide (NO) from the vascular endothelium regulates the tone of muscular arteries and resistance vasculature. Effects of NO on muscular arteries could be particularly important during exercise when shear stress may s
Externí odkaz:
https://doaj.org/article/3a593dd980bf4660aa27684372f3d59c
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
Background: Arterial stiffness, as measured by pulse wave velocity (PWV) is dependent on arterial blood pressure but whether this dependence varies with age is unknown. The objective of this study was to determine to what degree pressure-dependence v
Externí odkaz:
https://doaj.org/article/d2c8cbd0796544e8973012d561145df0
Publikováno v:
Healthcare Technology Letters (2019)
Mental stress is a major burden for our society. Invasive and non-invasive methods have been proposed to monitor and quantify it using various sensors on and off body. In this Letter, the authors investigated the use of the arm photoplethysmogram (PP
Externí odkaz:
https://doaj.org/article/581b1a681e8f4f04991b7c50edafef37
Autor:
Toby Andrew, Cassandra D Calloway, Sarah Stuart, Sang Hoon Lee, Raj Gill, Gail Clement, Philip Chowienczyk, Tim D Spector, Ana M Valdes
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22332 (2011)
The mitochondrial theory of ageing proposes that damage to mitochondria and diminished mitochondrial DNA (mtDNA) repair are major contributors to cellular dysfunction and age-related diseases. We investigate the prevalence of heteroplasmy in the mtDN
Externí odkaz:
https://doaj.org/article/acccda3c7bef451fbe3eeae8169618f5
Autor:
Luke Dancy, Ana Rita Cabaco, Andrew J. Webb, Ali Roomi, Kevin O'Gallagher, Philip Chowienczyk, Narbeh Melikian, Haotian Gu, Ajay M. Shah, Matthew Ryan
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology
Inorganic nitrite is a source of nitric oxide (NO) and is considered as a potential therapy in settings where endogenous NO bioactivity is reduced and left ventricular (LV) function impaired. However, the effects of nitrite on human cardiac contracti
Autor:
Haotian Gu, Knut Matre, Johannes Just Hjertaas, Philip Chowienczyk, John C. Chambers, Eva Gerdts, Sahrai Saeed, Eigir Einarsen
Publikováno v:
European Heart Journal-Cardiovascular Imaging
650–657
650–657
Aims First-phase ejection fraction (EF1), the EF at the time to peak aortic jet velocity, has been proposed as a novel marker of peak systolic function in aortic stenosis (AS). This study aimed to explore the association of myocardial contractility a
Autor:
Molly O'Callaghan-Latham, Geoffrey Charles-Edwards, Leanne Smith, Nicolas Basty, Eslem Kusaslan, Wendy L. Hall, Peter R. Ellis, Maria D'Annibale, Haris Shuaib, Lucy Francis, Dimitra Christodoulou, Brandon Whitcher, Vita Dikariyanto, Sarah Berry, May Robertson, Camille Palanche, Philip Chowienczyk
Publikováno v:
The American Journal of Clinical Nutrition
Dikariyanto, V, Smith, L, Francis, L, Robertson, M, Kusaslan, E, Callaghan-Latham, M, Palanche, C, D'Annibale, M, Christodoulou, D, Basty, N, Whitcher, B, Shuaib, H, Charles-Edwards, G, Chowienczyk, P, Ellis, P, Berry, S & Hall, W 2020, ' Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial. ', American Journal of Clinical Nutrition, vol. 111, no. 6, pp. 1178-1189 . https://doi.org/10.1093/ajcn/nqaa100
Dikariyanto, V, Smith, L, Francis, L, Robertson, M, Kusaslan, E, Callaghan-Latham, M, Palanche, C, D'Annibale, M, Christodoulou, D, Basty, N, Whitcher, B, Shuaib, H, Charles-Edwards, G, Chowienczyk, P, Ellis, P, Berry, S & Hall, W 2020, ' Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial. ', American Journal of Clinical Nutrition, vol. 111, no. 6, pp. 1178-1189 . https://doi.org/10.1093/ajcn/nqaa100
Background There is convincing evidence that daily whole almond consumption lowers blood LDL cholesterol concentrations, but effects on other cardiometabolic risk factors such as endothelial function and liver fat are still to be determined. Objectiv