Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Philip C. Gordge"'
1
Expression of enzymes of covalent protein modification during regulated and dysregulated proliferation of mammary epithelial cells: PKA, PKC and NMT
Autor: William R. Miller, Philip C Gordge, Roger A. Clegg
Publikováno v: Advances in Enzyme Regulation. 39:175-203
Three proteins are functionally interlinked in the targeting of protein phosphorylation catalyzed by the C-subunit of PKA: PKA itself, AKAPs and NMT. Furthermore, in a variety of biological contexts, mechanisms exist whereby PKA and PKC are able to m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1443cfc4bcdd2c876fb5775e98ebe2
https://doi.org/10.1016/s0065-2571(98)00011-9
Zobrazit plný text záznamu
2
Properties of a Resiniferatoxin-stimulated, Calcium Inhibited but Phosphatidylserine-dependent Kinase, which is Distinct from Protein Kinase C Isotypes α, β1γ, δ, ε and η
Autor: Philip C. Gordge, A.T. Evans, B. Thomas, Pawan Sharma, N. Shaun, Peter J. Parker, Fred J. Evans, W. J. Ryves
Publikováno v: Journal of Pharmacy and Pharmacology. 47:297-306
We have separated a resiniferatoxin-stimulated histone-kinase activity from human neutrophils, elicited mouse macrophages and murine alveolar macrophages by hydroxyapatite chromatography. The assay conditions for resiniferatoxin kinase were optimized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e9b0891d503a023a3fca46058f3e48d
https://doi.org/10.1111/j.2042-7158.1995.tb05799.x
Zobrazit plný text záznamu
4
Platelet protein phosphorylation and protein kinase C activation by phorbol esters with different biological activity and a novel synergistic response with Ca2+ ionophore
Autor: Susan F. Brooks, Fred J. Evans, A. Tudor Evans, Alex Toker, Philip C. Gordge, Alastair Aitken
Publikováno v: European Journal of Biochemistry. 188:431-437
Phorbol esters with different biological activities have been tested for their ability to induce the phosphorylation of human platelet proteins. We have shown that only the potent platelet aggregatory phorbol esters were able to stimulate the phospho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e951de79155e6dd48e97be9e78dd923a
https://doi.org/10.1111/j.1432-1033.1990.tb15420.x
Zobrazit plný text záznamu
5
The potent irritancy of the daphnane orthoester, resiniferatoxin, exhibits features of a mixed aetiology
Autor: Philip C. Gordge, A. Tudor Evans, Vaneeta Sahni, Fred J. Evans
Publikováno v: Journal of Pharmacy and Pharmacology. 44:361-363
Resiniferatoxin-induced erythema of mouse ear was shown to possess characteristics of both a phorbol ester-mediated response and that induced by the neurogenic irritant, capsaicin. Whereas the response to the phorbol ester, sapintoxin D, was delayed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04db27d451202b3753f9ea01d310d92
https://doi.org/10.1111/j.2042-7158.1992.tb03622.x
Zobrazit plný text záznamu
6
HL-60 cell differentiation induced by phorbol- and 12-deoxyphorbol-esters
Autor: Saša M. Dimitrijevic, Fred J. Evans, W. Jonathan Ryves, Philip C. Gordge
Publikováno v: Carcinogenesis. 15(11)
The human promyelocytic leukaemia cell (HL-60) undergoes differentiation into a macrophage-like form when exposed to both tumour promoting- and non-promoting phorbol esters. We have investigated the effect of the two non-promoting phorbol esters, 12-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d27689a9a5cd6f5f06b1a326958e92
https://pubmed.ncbi.nlm.nih.gov/7955099
Zobrazit plný text záznamu
7
12-Deoxyphorbol-13-O-phenylacetate-20-acetate is not protein kinase C-beta isozyme-selective in vivo
Autor: Fred J. Evans, W. J. Ryves, Philip C. Gordge, D K Ways, S C Kiley, Peter J. Parker, Andrée R. Olivier
Publikováno v: Carcinogenesis. 15(2)
The phorbol ester, 12-deoxyphorbol-13-O-phenylacetate-20-acetate (DOPPA) has been shown to activate specifically the protein kinase C (PKC)-beta 1 isozyme in vitro (1). We have investigated the potential of DOPPA as a PKC-beta 1/2 isozyme-specific ag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708eeb848643b67811bb9a88c89059e1
https://pubmed.ncbi.nlm.nih.gov/8313525
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje