Výsledky vyhledávání - "Philip C, Allen"

Akademický článek

Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

Autor: Kousaku Ohno, Lluis Samaranch, Piotr Hadaczek, John R. Bringas, Philip C. Allen, Vivek Sudhakar, Diane E. Stockinger, Christopher Snieckus, Michael V. Campagna, Waldy San Sebastian, Jerusha Naidoo, Haifeng Chen, John Forsayeth, Ernesto A. Salegio, Granger G.C. Hwa, Krystof S. Bankiewicz

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 47-54 (2019)

Here we evaluated the utility of MRI to monitor intrathecal infusions in nonhuman primates. Adeno-associated virus (AAV) spiked with gadoteridol, a gadolinium-based MRI contrast agent, enabled real-time visualization of infusions delivered either via

Externí odkaz: https://doaj.org/article/5a819b72674d4e9490c437bdab03d8bd

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Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates

Autor: Lluis Samaranch, John Forsayeth, Waldy San Sebastian, Krystof S. Bankiewicz, Ernesto A. Salegio, Philip C. Allen, Piotr Hadaczek, Haifeng Chen, Michael V. Campagna, Jerusha Naidoo, Granger G.C. Hwa, Kousaku Ohno, John Bringas, Vivek Sudhakar, Diane E. Stockinger, Christopher Snieckus

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 47-54 (2019)
Molecular Therapy. Methods & Clinical Development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e868c604fb9c50fcf1cdebefedd028e
http://www.sciencedirect.com/science/article/pii/S2329050118301232

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Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques

Autor: Diane E. Stockinger, Granger G.C. Hwa, Philip C. Allen, Sridhar Samineni, Sara M. Freeman, Jeffrey A. Roberts, Karen L. Bales

Publikováno v: Freeman, SM; Samineni, S; Allen, PC; Stockinger, D; Bales, KL; Hwa, GGC; et al.(2016). Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques. Psychoneuroendocrinology, 66, 185-194. doi: 10.1016/j.psyneuen.2016.01.014. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/3r165814

© 2016 Elsevier Ltd. Oxytocin (OT) is a neuropeptide that mediates a variety of complex social behaviors in animals and humans. Intranasal OT has been used as an experimental therapeutic for human conditions characterized by deficits in social funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60386c7eceabc201d3af342e081f1553
https://doi.org/10.1016/j.psyneuen.2016.01.014

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Targeted Delivery and Tolerability of MRI-Guided CED Infusion into the Cerebellum of Nonhuman Primates

Autor: Ernesto A. Salegio, Michael V. Campagna, Granger G.C. Hwa, Diane E. Stockinger, Philip C. Allen, Yuanquan Song

Publikováno v: Human gene therapy methods. 29(4)

This study explored the feasibility of intraparenchymal delivery (gadoteridol and/or Serotype 5 Adeno-Associated Viral Vector-enhanced Green Fluorescent Protein [AAV5-eGFP]) into the cerebellum of nonhuman primates using real-time magnetic resonance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3849b9bf1feb67067c8517a7be17aa87
https://pubmed.ncbi.nlm.nih.gov/29953257

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Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity

Autor: Krystof S. Bankiewicz, Erich Mohr, Matthias Luz, H. Christian Fibiger, John Bringas, Diane E. Stockinger, Kristen J. Nikula, Chris Boiko, Philip C. Allen, Owen T. Lewis, Max Woolley

Publikováno v: Archives of Toxicology
Archives of toxicology, vol 92, iss 7

Glial cell line-derived neurotrophic factor (GDNF) has demonstrated neurorestorative and neuroprotective effects in rodent and nonhuman primate models of Parkinson’s disease. However, continuous intraputamenal infusion of GDNF (100 µg/day) resulte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe0dbbe8156e443e12d653a0147f36e
https://pubmed.ncbi.nlm.nih.gov/29785638

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Pharmacokinetics of Tenofovir following Intravaginal and Intrarectal Administration of Tenofovir Gel to Rhesus Macaques

Autor: Nicole White, Philip C. Allen, Angela D. M. Kashuba, Jeffrey A. Roberts, Ruili Wang, Joseph Romano, Jeremy Nuttall

Publikováno v: Antimicrobial Agents and Chemotherapy. 56:103-109

Tenofovir gel (1%) is being developed as a microbicide for the prevention of human immunodeficiency virus (HIV) infection and has been shown to reduce transmission to women by 39%. The gel also prevents infection in macaques when applied intravaginal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6515c27d04aa5d26b63667253d2b7443
https://doi.org/10.1128/aac.00597-11

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Microsatellite markers for standardized genetic management of captive colonies of rhesus macaques (Macaca mulatta)

Autor: Andrea Von Dollen, Jennifer D. Kurushima, David Glenn Smith, Jeffrey Rogers, Betsy Ferguson, Ona Alminas, Philip C. Allen, Nicholas W. Lerche, Sreetharan Kanthaswamy

Publikováno v: American Journal of Primatology. 68:73-95

To preserve genetic variability and minimize genetic subdivision among captive Macaca mulatta at each of the U.S. National Institutes of Health (NIH)-sponsored regional research colonies, the genetic structure of each colony must be characterized. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2efccc73286cf2f87d53259abc5e967
https://doi.org/10.1002/ajp.20207

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Thermal and photo-oxidative degradation of poly (5′,6′-bis(trifluoromethyl)-bicyclo [2.2.2] octa-5′,7′-diene-2′,3′-diyl)-1,2-ethenediyl, the Durham polyacetylene precursor polymer, and polyacetylene

Autor: Lucy Margaret Connors, W. James Feast, Chris S Brown, Philip C Allen, Nick S Walker, Munir M. Ahmad, Peter I Clemenson, Jeremy N. Winter, D. C. Bott

Publikováno v: Polymer. 33:4711-4716

The photo-oxidation of the precursor polymer to Durham polyacetylene has been studied by thermal analysis and ultra-violet, infra-red and solid-state nuclear magnetic resonance spectroscopies. It is concluded that the process that is involved in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::902319d803874a6b2dd13a9de380552b
https://doi.org/10.1016/0032-3861(92)90681-l

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Comparative efficacy of a canine distemper-measles and a standard measles vaccine for immunization of rhesus macaques (Macaca mulatta)

Autor: Kari L, Christe, Michael B, McChesney, Abigail, Spinner, Ann N, Rosenthal, Philip C, Allen, Celia R, Valverde, Jeffrey A, Roberts, Nicholas W, Lerche

Publikováno v: Comparative medicine. 52(5)

Measles virus (MV), a highly infective paramyxovirus, has caused sporadic epizootics characterized by high morbidity and increased mortality in nonhuman primates. Measles vaccines for human use, although effective, are cost prohibitive for use in pri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4138e7d6ba7ebabaa550846c2d82c3d3
https://pubmed.ncbi.nlm.nih.gov/12405642

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