Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Philip B. Miner"'
Publikováno v:
Clinical and Translational Gastroenterology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e761567f618d2ff5fec7f8c492c6c894
https://doi.org/10.14309/ctg.0000000000000598
https://doi.org/10.14309/ctg.0000000000000598
Autor:
Philip B Miner
Publikováno v:
Expert Review of Gastroenterology & Hepatology. 14:71-84
Introduction: As an analogue of uroguanylin plecanatide binds to the Guanylate Cyclase-C receptor activating fluid and ion secretion in the small intestine with the same pH-dependent binding kinetics as the natural ligand. Plecanatide has been FDA ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404b2d52c428be51db76e67b528b9d93
https://doi.org/10.1080/17474124.2020.1722101
https://doi.org/10.1080/17474124.2020.1722101
Autor:
David N Roberts, Philip B Miner
Publikováno v:
Drug, Healthcare and Patient Safety, Vol 2011, Iss default, Pp 1-8 (2011)
David N Roberts1, Philip B Miner21Department of Internal Medicine, Digestive Diseases Section, University of Oklahoma, 2Oklahoma Foundation for Digestive Research, Oklahoma City, Oklahoma, USAAbstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) ar
Externí odkaz:
https://doaj.org/article/86f701ba82134d9385376d54a2dbe6a2
Autor:
David A. Johnson, Charles Pollack, Philip B. Miner, Jing Li, Philip O. Katz, Sergio C. Gatoulis
Publikováno v:
Advances in Therapy
Introduction Reflux symptoms are frequently associated with esophageal acid exposure. However, other potential causes unrelated to acid secretion are possible, and the relationship between acid control and symptomatic improvement remains unclear. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ee609793ee85e7a974496fcf959240
https://doi.org/10.1007/s12325-018-0792-z
https://doi.org/10.1007/s12325-018-0792-z
Autor:
Philip B. Miner
Publikováno v:
Expert Opinion on Pharmacotherapy. 19:1381-1388
Elobixibat is the first in class ileal bile acid transporter (IBAT) inhibitor. IBAT inhibitors block ileal absorption of bile acids by: (1) interrupting the enterohepatic circulation of bile resulting in a fall in serum cholesterol and (2) increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91071c7c7674be7dfd8a3c7efc12f3c3
https://doi.org/10.1080/14656566.2018.1508450
https://doi.org/10.1080/14656566.2018.1508450
Autor:
Kunwar Shailubhai, Blas Prieto, Marianela De La Portilla, Philip B. Miner, Gregory J Wiener, William Koltun, Patrick Griffin, Laura Barrow, Mary Beth Layton, Leslie Magnus
Publikováno v:
The American Journal of Gastroenterology
Objectives: This study assessed the efficacy and safety of plecanatide, a guanylate cyclase-C (GC-C) agonist and the first uroguanylin analog approved for the treatment of chronic idiopathic constipation (CIC). Methods: This phase III, multicenter, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032edc3391e4beb74e947050c6f17d7f
https://doi.org/10.1038/ajg.2016.611
https://doi.org/10.1038/ajg.2016.611
Autor:
Philip B. Miner
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 17(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1621dd1c66a6494a25aa6dac01c25b5
https://pubmed.ncbi.nlm.nih.gov/30153518
https://pubmed.ncbi.nlm.nih.gov/30153518
Autor:
Philip B. Miner
Publikováno v:
Drug safety. 42(5)
Plecanatide, a uroguanylin analog, activates the guanylate cyclase C receptors in the epithelial lining of the gastrointestinal tract in a pH-dependent fashion initiating (1) the conversion of intracellular guanosine triphosphate to cyclic guanosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b45e01057cfdeaa0f140ccdd00ad75
https://pubmed.ncbi.nlm.nih.gov/30649746
https://pubmed.ncbi.nlm.nih.gov/30649746
Autor:
Philip B. Miner
Publikováno v:
Expert opinion on pharmacotherapy. 19(2)
Uroguanylin interacting with intestinal Guanylate Cyclase C (GC-C) receptors plays an important role in gastrointestinal fluid and electrolyte homeostasis. Plecanatide is the first uroguanylin analog that stimulates GC-C receptors on gastrointestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d37dc4639dd4be11d853ee0abec4e4
https://pubmed.ncbi.nlm.nih.gov/29376436
https://pubmed.ncbi.nlm.nih.gov/29376436
Autor:
Philip B. Miner
Publikováno v:
The American Journal of Gastroenterology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d090c4b51d96cf4a836037b33be0173e
https://pubmed.ncbi.nlm.nih.gov/29109497
https://pubmed.ncbi.nlm.nih.gov/29109497