Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Philip A. de Groot"'
Autor:
Eline D. Postma, Lucas G. F. Couwenberg, Roderick N. van Roosmalen, Jordi Geelhoed, Philip A. de Groot, Pascale Daran-Lapujade
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Saccharomyces cerevisiae, whose evolutionary past includes a whole-genome duplication event, is characterized by a mosaic genome configuration with substantial apparent genetic redundancy. This apparent redundancy raises questions about the
Externí odkaz:
https://doaj.org/article/9fec022a25b345548d1f5c50c2ad643e
Autor:
Tyler W. Doughty, Iván Domenzain, Aaron Millan-Oropeza, Noemi Montini, Philip A. de Groot, Rui Pereira, Jens Nielsen, Céline Henry, Jean-Marc G. Daran, Verena Siewers, John P. Morrissey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Fermentation parameters of industrial processes are often not the ideal growth conditions for industrial microbes. Here, the authors reveal that young genes are more responsive to environmental stress than ancient genes using a new gene age assignmen
Externí odkaz:
https://doaj.org/article/453efe3e004741ae8e4b9a901b4ed692
Autor:
Mark Levisson, Constantinos Patinios, Sascha Hein, Philip A. de Groot, Jean-Marc Daran, Robert D. Hall, Stefan Martens, Jules Beekwilder
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Anthocyanins are polyphenolic pigments which provide pink to blue colours in fruits and flowers. There is an increasing demand for anthocyanins, as food colorants and as health-promoting substances. Plant production of anthocyanin
Externí odkaz:
https://doaj.org/article/915e3fb1d6ae4254a995c1d7a9a43c26
Publikováno v:
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-18 (2017)
Abstract Background The ease of use of CRISPR-Cas9 reprogramming, its high efficacy, and its multiplexing capabilities have brought this technology at the forefront of genome editing techniques. Saccharomyces pastorianus is an aneuploid interspecific
Externí odkaz:
https://doaj.org/article/9bcb5ab347a34aff8b7dfec10477d2e8
Autor:
Rachel Gehlen, Roxanne G. Moesbergen, CuiCui Bai, Philip G. de Groot, A.J.Gerard Jansen, Joost C.M. Meijers, Bas de Laat, Jasper A. Remijn
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 5, Pp 102470- (2024)
Background: Life-long vitamin K antagonist (VKA) therapy is recommended as a standard of care in antiphospholipid syndrome (APS) patients with thrombosis. Concerns have been raised about the validity of international normalized ratio (INR) measuremen
Externí odkaz:
https://doaj.org/article/bd6652518e4547ebb4598a4644552091
Autor:
Jinmi Zou, Siyu Sun, Ilaria De Simone, Hugo ten Cate, Philip G. de Groot, Bas de Laat, Mark Roest, Johan W.M. Heemskerk, Frauke Swieringa
Publikováno v:
TH Open, Vol 08, Iss 02, Pp e232-e242 (2024)
Background Agonist-induced platelet activation, with the integrin αIIbβ3 conformational change, is required for fibrinogen binding. This is considered reversible under specific conditions, allowing a second phase of platelet aggregation. The signal
Externí odkaz:
https://doaj.org/article/a1a44a63b65c416f94bc44b92ad11959
Autor:
Romy M.W. Kremers, Stéphane Zuily, Hilde Kelchtermans, Tessa C. Peters, Saartje Bloemen, Véronique Regnault, H. Coenraad Hemker, Philip G. de Groot, Denis Wahl, Bas de Laat
Publikováno v:
Blood Advances, Vol 2, Iss 11, Pp 1315-1324 (2018)
Abstract: Antiphospholipid syndrome (APS) is a condition in which the presence of antibodies against phospholipid-binding proteins is associated with thrombophilia and/or pregnancy morbidity. Although antiphospholipid antibodies have anticoagulant ch
Externí odkaz:
https://doaj.org/article/7767c9c787474847b0d80b489c894b54
Autor:
Paolo Durigutto, Claudia Grossi, Maria Orietta Borghi, Paolo Macor, Francesca Pregnolato, Elena Raschi, Michael P. Myers, Philip G. de Groot, Pier Luigi Meroni, Francesco Tedesco
Publikováno v:
Haematologica, Vol 104, Iss 4 (2019)
Clinical studies have reported different diagnostic/predictive values of antibodies to domain 1 or 4/5 of β2glycoproteinI in terms of risk of thrombosis and pregnancy complications in patients with antiphospholipid syndrome. To obtain direct evidenc
Externí odkaz:
https://doaj.org/article/49cd3e6bfacb4bf988f49f0dfaf1da92
Autor:
Romy de Laat-Kremers, Denis Wahl, Stéphane Zuily, Marisa Ninivaggi, Veronique Regnault, Jacek Musial, Philip G. de Groot, Katrien Devreese, Bas de Laat
Publikováno v:
Blood. 140:8388-8390
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30d510fb6638a5ff95c826bf100dfc65
https://doi.org/10.1182/blood-2022-163181
https://doi.org/10.1182/blood-2022-163181
Autor:
Nikolett Wohner, Peter J. Lenting, Bas de Laat, Philip G de Groot, Vincent Muczynski, Silvie Sebastian, Dana Huskens
Publikováno v:
Journal of Thrombosis and Haemostasis, 20(3), 755-766. Wiley
Background Platelet-binding Von Willebrand Factor (VWF) strings assemble upon stimulated secretion from endothelial cells. Objectives To investigate the efficiency of platelet binding to multi-molecular VWF bundles secreted from endothelial cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a923af7e5a12044e9ffd80f58a79b2e2
https://cris.maastrichtuniversity.nl/en/publications/29a0b9da-23fe-420b-9e20-3be13c5b6076
https://cris.maastrichtuniversity.nl/en/publications/29a0b9da-23fe-420b-9e20-3be13c5b6076