Zobrazeno 1 - 10
of 460
pro vyhledávání: '"Philip A. Wolf"'
Autor:
Hugo J. Aparicio, Jayandra J. Himali, Alexa S. Beiser, Kendra L. Davis‐Plourde, Ramachandran S. Vasan, Carlos S. Kase, Philip A. Wolf, Sudha Seshadri
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)
BackgroundWe investigated how body weight affects survival after stroke, leveraging the availability of multiple prestroke body mass index (BMI) measurements and using a nested case‐control design in a community‐based sample. Methods and ResultsW
Externí odkaz:
https://doaj.org/article/febd8dae1bf746d4ac87bb1765fb2add
Autor:
José R. Romero, Sarah R. Preis, Alexa Beiser, Charles DeCarli, Ralph B. D'Agostino, Philip A. Wolf, Ramachandran S. Vasan, Joseph F. Polak, Sudha Seshadri
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 3 (2016)
BackgroundCarotid atherosclerosis is associated with subclinical ischemic cerebrovascular disease, but its role in hemorrhage‐prone small vessel disease—represented by cerebral microbleed (CMB)—is unclear, although vascular risk factors underli
Externí odkaz:
https://doaj.org/article/7d0dfdef4e6c44a3807fd22b08140af0
Autor:
Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Chao-Qiang Lai, Serkalem Demissie, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph B. D'Agostino, Sr., Christopher J. O'Donnell
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 5, Pp 990-996 (2006)
Genetic variation at the apolipoprotein A5 gene (APOA5) is associated with increased triglyceride concentrations, a risk factor for atherosclerosis. Carotid intimal medial thickness (IMT) is a surrogate measure of atherosclerosis burden. We sought to
Externí odkaz:
https://doaj.org/article/58149b458b7545428f0771051665d54e
Autor:
Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph A. D’Agostino, Sr., Christopher J. O’Donnell
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1868-1875 (2004)
The aim of this study was to determine the association between APOE genotype and carotid atherosclerosis, defined as intimal-medial thickness (IMT) and stenosis, and to assess if other cardiovascular risk factors modify this association. A total of 1
Externí odkaz:
https://doaj.org/article/7a98ff5d204b4942874631ecff9fff68
Autor:
David J. Werring, Yunyun Xiong, Sudha Seshadri, Yuki Takashima, Philip A. Wolf, Vincent Mok, Yusuke Yakushiji, Lenore J. Launer, Sarah R. Preis, Hideo Hara, Jose R. Romero, Toshio Imaizumi, Yoshito Tsushima, Alexa S. Beiser, Mark A. van Buchem, Duncan Wilson, Thanh G. Phan, Zhaolu Wang, Gareth Ambler, Charles DeCarli, Velandai Srikanth, Katsuhiko Kohara, Ding Ding, Villi Gudnason, Hyung-Min Kwon, Shuhei Yamaguchi, Andreas Charidimou
Publikováno v:
Neurology, vol 92, iss 10
Neurology, 92(10), E1086-E1097
Neurology
Neurology, 92(10), E1086-E1097
Neurology
ObjectiveWe investigated differences in the anatomical distribution of cerebral microbleeds (CMBs) on MRI, hypothesized to indicate the type of underlying cerebral small vessel disease (SVD), between Eastern and Western general populations.MethodsWe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236f3f352ce10b9bf18690d76e241def
https://doi.org/10.1212/wnl.0000000000007039
https://doi.org/10.1212/wnl.0000000000007039
Autor:
Stephen R Williams, Qiong Yang, Fang Chen, Xuan Liu, Keith L Keene, Paul Jacques, Wei-Min Chen, Galit Weinstein, Fang-Chi Hsu, Alexa Beiser, Liewei Wang, Ebony Bookman, Kimberly F Doheny, Philip A Wolf, Michelle Zilka, Jacob Selhub, Sarah Nelson, Stephanie M Gogarten, Bradford B Worrall, Sudha Seshadri, Michèle M Sale, Genomics and Randomized Trials Network, Framingham Heart Study
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004214 (2014)
Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such as stroke, cardiovascular di
Externí odkaz:
https://doaj.org/article/285e16861ae94f8baee356f1e4b0a31a
Autor:
Joshua C Bis, Anita DeStefano, Xiaoming Liu, Jennifer A Brody, Seung Hoan Choi, Benjamin F J Verhaaren, Stéphanie Debette, M Arfan Ikram, Eyal Shahar, Kenneth R Butler, Rebecca F Gottesman, Donna Muzny, Christie L Kovar, Bruce M Psaty, Albert Hofman, Thomas Lumley, Mayetri Gupta, Philip A Wolf, Cornelia van Duijn, Richard A Gibbs, Thomas H Mosley, W T Longstreth, Eric Boerwinkle, Sudha Seshadri, Myriam Fornage
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99798 (2014)
BACKGROUND:Stroke, the leading neurologic cause of death and disability, has a substantial genetic component. We previously conducted a genome-wide association study (GWAS) in four prospective studies from the Cohorts for Heart and Aging Research in
Externí odkaz:
https://doaj.org/article/2645886fc6524434813771f7b79b3270
Autor:
Jose Rafael Romero, Melissa eMercado, Alexa S Beiser, Aleksandra ePikula, Sudha eSeshadri, Margaret eKelly-Hayes, Philip A Wolf, Carlos S Kase
Publikováno v:
Frontiers in Neurology, Vol 4 (2013)
Background/ objective: Transient global amnesia (TGA) is a temporary amnestic syndrome characterized by lack of other focal neurological deficits. Cerebrovascular disease, migraine and seizures have been suggested as underlying mechanisms. TGA may be
Externí odkaz:
https://doaj.org/article/4b72836bc3ba46c9a554a83e8a8e137a
Autor:
Gyungah Jun, Juliet A Moncaster, Carolina Koutras, Sudha Seshadri, Jacqueline Buros, Ann C McKee, Georges Levesque, Philip A Wolf, Peter St George-Hyslop, Lee E Goldstein, Lindsay A Farrer
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43728 (2012)
Multiple lines of evidence suggest that specific subtypes of age-related cataract (ARC) and Alzheimer disease (AD) are related etiologically. To identify shared genetic factors for ARC and AD, we estimated co-heritability of quantitative measures of
Externí odkaz:
https://doaj.org/article/c8f03ea3915946bb98eea25a66147125
Autor:
Charles DeCarli, Sarah R. Preis, Katherine J. Bangen, Mark W. Bondi, Lisa Delano-Wood, Rhoda Au, Philip A. Wolf, Adam M. Brickman, David J. Libon
Publikováno v:
Alzheimer Disease & Associated Disorders. 32:50-56
Introduction We examined associations between magnetic resonance imaging (MRI) markers of cerebrovascular disease and neurodegeneration with mild cognitive impairment (MCI) diagnosis at baseline and conversion from normal cognition to MCI at follow-u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a702f500d5182d9c31de337ad70acd58
https://doi.org/10.1097/wad.0000000000000215
https://doi.org/10.1097/wad.0000000000000215