Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Philip A. Waghorn"'
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is an increasing cause of chronic liver disease characterized by steatosis, inflammation, and fibrosis which can lead to cirrhosis, hepatocellular carcinoma, and mortality. Quantitative, noninvasive metho
Externí odkaz:
https://doaj.org/article/327b39d031bd46df9de3f4c4aba0cf0e
Autor:
Philip A. Waghorn, Diego S. Ferreira, Derek J. Erstad, Nicholas J. Rotile, Ricard Masia, Chloe M. Jones, Chuantao Tu, Mozhdeh Sojoodi, Yin-ching I. Chen, Franklin Schlerman, Jeremy Wellen, Robert V. P. Martinez, Kenneth K. Tanabe, Bryan C. Fuchs, Peter Caravan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/5dff62519d184cbbbad8e11434fc02ef
Autor:
Yin-Ching Chen, Philip A. Waghorn, Ivy A. Rosales, Gunisha Arora, Derek J. Erstad, Nicholas J. Rotile, Chloe M. Jones, Diego S. Ferreira, Lan Wei, Robert V. P. Martinez, Franklin J. Schlerman, Jeremy Wellen, Bryan C. Fuchs, Robert B. Colvin, Ilknur Ay, Peter Caravan
Publikováno v:
Journal of the American Society of Nephrology.
Autor:
Katherine A. Vallis, Madalena Tarsounas, Tom Brown, Afaf H. El-Sagheer, Martin R. Gill, Philip A. Waghorn, Bas M. Bavelaar, Mark R. Jackson
Telomerase is expressed in the majority (>85%) of tumors, but has restricted expression in normal tissues. Long-term telomerase inhibition in malignant cells results in progressive telomere shortening and reduction in cell proliferation. Here we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28019c487d490888c1e3a57acc17d76
https://doi.org/10.1158/0008-5472.c.6511004.v1
https://doi.org/10.1158/0008-5472.c.6511004.v1
Autor:
Katherine A. Vallis, Madalena Tarsounas, Tom Brown, Afaf H. El-Sagheer, Martin R. Gill, Philip A. Waghorn, Bas M. Bavelaar, Mark R. Jackson
The supplementary data file contains mass spectrometry (MS) and size exclusion chromatography (SEC) data to confirm DTPA-, 111In-, and fluorophore-labeling of oligonucleotides, TRAP assay control experiments, quantification of fluorophore-oligonucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03923d9e8b7d739f4dcdf22d1291c251
https://doi.org/10.1158/0008-5472.22421717.v1
https://doi.org/10.1158/0008-5472.22421717.v1
Autor:
Mozhdeh Sojoodi, Derek J. Erstad, Franklin J. Schlerman, Peter Caravan, Chuantao Tu, Nicholas J. Rotile, Kenneth K. Tanabe, Bryan C. Fuchs, Ricard Masia, Diego dos Santos Ferreira, Jeremy W. Wellen, Philip A. Waghorn, Yin-ching I. Chen, Chloe M. Jones, Robert V. Martinez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Non-alcoholic steatohepatitis (NASH) is an increasing cause of chronic liver disease characterized by steatosis, inflammation, and fibrosis which can lead to cirrhosis, hepatocellular carcinoma, and mortality. Quantitative, noninvasive methods for ch
Autor:
Jonathan R. Dilworth, Helena C. Quilter, Gabriele Kociok-Köhn, Rüdiger M. Exner, Sophia Sarpaki, Fernando Cortezon-Tamarit, Sofia I. Pascu, Philip A. Waghorn, Ruggero Dondi, Ian M. Eggleston, Valeria Ciaffaglione, Haobo Ge, Stanley W. Botchway, Samuel P. Godfrey
Publikováno v:
Bioconjugate Chemistry
Over the past decade, porphyrin derivatives have emerged as invaluable synthetic building blocks and theranostic kits for the delivery of cellular fluorescence imaging and photodynamic therapy. Tetraphenylporphyrin (TPP), its metal complexes, and rel
Autor:
Peter Caravan, Nicholas J. Rotile, Franklin J. Schlerman, Chuantao Tu, Yin-ching I. Chen, Ricard Masia, Derek J. Erstad, Diego dos Santos Ferreira, Jeremy W. Wellen, Philip A. Waghorn, Bryan C. Fuchs, Kenneth K. Tanabe, Chloe M. Jones, Mozhdeh Sojoodi, Robert V. Martinez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Autor:
Ole Tietz, Philip A. Waghorn, Robert Carlisle, Mark R. Jackson, Lei Song, Martin R. Gill, Irini Skaripa-Koukelli, Madalena Tarsounas, Bas M. Bavelaar, Sarah Able, Katherine A. Vallis
Publikováno v:
Molecular Pharmaceutics
Telomerase represents an attractive target in oncology as it is expressed in cancer but not in normal tissues. The oligonucleotide inhibitors of telomerase represent a promising anticancer strategy, although poor cellular uptake can restrict their ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc6ba5b5cd67a99da8a217626dd2550
https://ora.ox.ac.uk/objects/uuid:ef1fdf06-d47c-4d62-b7f0-c056d58b0ace
https://ora.ox.ac.uk/objects/uuid:ef1fdf06-d47c-4d62-b7f0-c056d58b0ace
Autor:
Peter Caravan, Diego dos Santos Ferreira, Nicholas J. Rotile, Richard L. Gieseck, Kenneth K. Tanabe, Gunisha Arora, Thomas A. Wynn, Bryan C. Fuchs, Philip A. Waghorn
Publikováno v:
Invest Radiol
RATIONALE AND OBJECTIVES: Fibrosis is characterized by progressive replacement of normal tissue by extracellular matrix. Diagnosis relies on biopsies as noninvasive methods for detection and quantification of fibrosis are still limited. This work aim