Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Philip A Mudd"'
Autor:
Michael J. Pajor, Satish Munigala, Dan Reynolds, Julie Zeigler, Danaye Gebru, Phillip V. Asaro, Steven J. Lawrence, Stephen Y. Liang, Philip A. Mudd
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Objectives We sought to develop an evidence‐based tool to risk stratify patients diagnosed with seasonal influenza in the emergency department (ED). Methods We performed a single‐center retrospective cohort study of all adult patients di
Externí odkaz:
https://doaj.org/article/4a7c125fe3834231929440601df35e16
Autor:
Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W. Goss, Jane A. O’Halloran, Philip A. Mudd, Mario Roederer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The association of specific immune cell types with SARS-CoV-2 severity is not fully understood. Here the authors analyse PBMC from individuals recovered from COVID-19 and propose immune cell signatures post recovery that are associated with disease s
Externí odkaz:
https://doaj.org/article/4332ecc498cb426a98bc215965288a51
Autor:
Lihua Wang, Daniel Western, Jigyasha Timsina, Charlie Repaci, Won-Min Song, Joanne Norton, Pat Kohlfeld, John Budde, Sharlee Climer, Omar H. Butt, Daniel Jacobson, Michael Garvin, Alan R. Templeton, Shawn Campagna, Jane O’Halloran, Rachel Presti, Charles W. Goss, Philip A. Mudd, Beau M. Ances, Bin Zhang, Yun Ju Sung, Carlos Cruchaga
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106408- (2023)
Summary: Identification of proteins dysregulated by COVID-19 infection is critically important for better understanding of its pathophysiology, building prognostic models, and identifying new targets. Plasma proteomic profiling of 4,301 proteins was
Externí odkaz:
https://doaj.org/article/0a25c4f99ec54638a4fc590b424af29d
Autor:
Marios Koutsakos, Jackson S Turner, M Cristina Vazquez Guillamet, Daniel Reynolds, Tingting Lei, Derek E Byers, Ali H Ellebedy, Philip A Mudd
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract Objectives There is an increasing appreciation for the need to study mucosal antibody responses in humans. Our aim was to determine the utility of different types of samples from the human respiratory tract, specifically nasopharyngeal (NP)
Externí odkaz:
https://doaj.org/article/0889cf52f04a40f68c7ee341b9a9fdcb
Autor:
Frank J. Lin, Alexa Michelle Altman Doss, Hannah G. Davis-Adams, Lucas J. Adams, Christopher H. Hanson, Laura A. VanBlargan, Chieh-Yu Liang, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O’Shaughnessy, Saravanan Raju, Fang R. Zhao, Elise Rizzi, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson S. Turner, Jane A. O’Halloran, Rachel M. Presti, Daved H. Fremont, Peggy L. Kendall, Ali H. Ellebedy, Philip A. Mudd, Michael S. Diamond, Ofer Zimmerman, Brian J. Laidlaw
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAlthough SARS-CoV-2 vaccines have proven effective in eliciting a protective immune response in healthy individuals, their ability to induce a durable immune response in immunocompromised individuals remains poorly understood. Primary antib
Externí odkaz:
https://doaj.org/article/09d941fbe1f542eca1d74a7632944273
Autor:
Bruce K. Patterson, Harish Seethamraju, Kush Dhody, Michael J. Corley, Kazem Kazempour, Jay Lalezari, Alina P.S. Pang, Christopher Sugai, Eisa Mahyari, Edgar B. Francisco, Amruta Pise, Hallison Rodrigues, Helen L. Wu, Gabriela M. Webb, Byung S. Park, Scott Kelly, Nader Pourhassan, Alina Lelic, Lama Kdouh, Monica Herrera, Eric Hall, Benjamin N. Bimber, Matthew Plassmeyer, Raavi Gupta, Oral Alpan, Jane A. O’Halloran, Philip A. Mudd, Enver Akalin, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
International Journal of Infectious Diseases, Vol 103, Iss , Pp 25-32 (2021)
Objective: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global pandemic. Emerging results indicate a dysregulated immune response. Given the role of CCR5 in immune cell migration and inflammation, we investigat
Externí odkaz:
https://doaj.org/article/aa64df75735341c59242e660d8c57951
Autor:
M. Cristina Vazquez Guillamet, MD, Hrishikesh S. Kulkarni, MD, MSCI, Kevin Montes, MD, Maanasi Samant, MD, Preet A. Shaikh, MD, Kevin Betthauser, PharmD, Philip A. Mudd, MD, PhD, Daniel Reynolds, MD, Jane O’Halloran, MD, PhD, Patrick Lyons, MD, Colleen McEvoy, MD, Rodrigo Vazquez Guillamet, MD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 2, p e0343 (2021)
Objectives:. To describe the infectious complications and interleukin-6 trajectories in mechanically ventilated patients with coronavirus disease 2019. Design:. Retrospective cohort study. Setting:. ICUs at Washington University-Barnes Jewish Hospita
Externí odkaz:
https://doaj.org/article/55e0430d02af4a568875531c9f546c26
Autor:
Davide Scozzi, Marlene Cano, Lina Ma, Dequan Zhou, Ji Hong Zhu, Jane A. O’Halloran, Charles Goss, Adriana M. Rauseo, Zhiyi Liu, Sanjaya K. Sahu, Valentina Peritore, Monica Rocco, Alberto Ricci, Rachele Amodeo, Laura Aimati, Mohsen Ibrahim, Ramsey Hachem, Daniel Kreisel, Philip A. Mudd, Hrishikesh S. Kulkarni, Andrew E. Gelman
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Background Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could be used to predict the risk of poor COVID-19 outcomes remains undetermined.Me
Externí odkaz:
https://doaj.org/article/18f9da8346e44ec09eb8792466de3b9a
Autor:
Kenneth E. Remy, Monty Mazer, David A. Striker, Ali H. Ellebedy, Andrew H. Walton, Jacqueline Unsinger, Teresa M. Blood, Philip A. Mudd, Daehan J. Yi, Daniel A. Mannion, Dale F. Osborne, R. Scott Martin, Nitin J. Anand, James P. Bosanquet, Jane Blood, Anne M. Drewry, Charles C. Caldwell, Isaiah R. Turnbull, Scott C. Brakenridge, Lyle L. Moldwawer, Richard S. Hotchkiss
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2021)
COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained vira
Externí odkaz:
https://doaj.org/article/e8dd85cce0b24e16aeb05e045c745304
Autor:
Jackson S. Turner, Aaron Day, Wafaa B. Alsoussi, Zhuoming Liu, Jane A. O’Halloran, Rachel M. Presti, Bruce K. Patterson, Sean P. J. Whelan, Ali H. Ellebedy, Philip A. Mudd
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Prolonged shedding of viral RNA occurs in some individuals following SARS-CoV-2 infection. We perform comprehensive immunologic evaluation of one individual with prolonged shedding. The case subject recovered from severe COVID-19 and tested positive
Externí odkaz:
https://doaj.org/article/726c86b25c71472686c5fd888af25739