Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Philip A Barker"'
Autor:
Aaron D Johnstone, Robin M Hallett, Andrés de Léon, Bruno Carturan, Julien Gibon, Philip A Barker
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199570 (2018)
Axons normally degenerate during development of the mammalian nervous system, but dysregulation of the same genetically-encoded destructive cellular machinery can destroy crucial structures during adult neurodegenerative diseases. Nerve growth factor
Externí odkaz:
https://doaj.org/article/6268038ca52446609ffc32b01461f43d
Autor:
Perrine Gaub, Andrès de Léon, Julien Gibon, Vincent Soubannier, Geneviève Dorval, Philippe Séguéla, Philip A Barker
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150601 (2016)
Neurotrophins activate intracellular signaling pathways necessary for neuronal survival, growth and apoptosis. The most abundant neurotrophin in the adult brain, brain-derived neurotrophic factor (BDNF), is first synthesized as a proBDNF precursor an
Externí odkaz:
https://doaj.org/article/9ec6215505df4cf3be85d54172e79ee7
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60091 (2013)
Photoreceptor neurons (R cells) in the Drosophila eye define a map of visual space by connecting to targets in distinct layers of the optic lobe, with R1-6 cells connecting to the lamina (the first optic ganglion) and R7 and R8 cells connecting to th
Externí odkaz:
https://doaj.org/article/ff5dd81bc1ee45e293d2d0f91a730859
Publikováno v:
J Neurosci
The activation of self-destructive cellular programs helps sculpt the nervous system during development, but the molecular mechanisms used are not fully understood. Prior studies have investigated the role of the APP in the developmental degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3463a4ac007dafe9282566d85fa23a5
https://doi.org/10.1523/jneurosci.0162-22.2022
https://doi.org/10.1523/jneurosci.0162-22.2022
Autor:
Marcela Laura Chaki Borrás, Georgia Colbran, David R. G. Mitchell, Philip J. Barker, Ronald Sluyter, Konstantin Konstantinov
Publikováno v:
Journal of Biomedical Materials Research Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d575acc7f7a3b9946fb1b422c72edf85
https://doi.org/10.1002/jbm.a.37524
https://doi.org/10.1002/jbm.a.37524
Autor:
Andrew C. Smith, Peter M. Wynn, Philip A. Barker, Melanie J. Leng, Steve R. Noble, Andrew Stott
Publikováno v:
International Journal of Speleology, Vol 45, Iss 1, Pp 1-9 (2016)
Palaeoclimate records from northern Iberia are becoming increasingly sought after as this region is one of the most southerly terrestrial locations in Europe to have its climate dictated principally by the North Atlantic. Terrestrial records therefor
Externí odkaz:
https://doaj.org/article/f4279ff07de0454faf75122d52432640
Publikováno v:
Journal of Pain Research. 13:1223-1241
Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation, and survival of sympathetic and sensory afferent neurons during development. A substantial body of evidence, based on both animal and human studies, demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3886bf05ae8c02fd246ac822a71e78b3
https://doi.org/10.2147/jpr.s247472
https://doi.org/10.2147/jpr.s247472
Autor:
Yaser Rehman, Alexander Morlando, Vitor Sencadas, Philip J. Barker, Konstantin Konstantinov, Jared McNamara
Publikováno v:
Journal of Materials Science. 55:8095-8108
The use of TiO2 nanoparticles in sunscreen products has raised concern over their oxidative potential and adverse health effects brought about by their propensity to produce free radicals when exposed to UV radiation. In this study, an investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca03dcd162a5a4819af819329f9d1e9
https://doi.org/10.1007/s10853-020-04598-3
https://doi.org/10.1007/s10853-020-04598-3
Autor:
Marcela Chaki Borras, Shahnaz Bakand, Konstantin Konstantinov, Yaser Rehman, Philip J. Barker, Ronald Sluyter, Alexander Morlando
Publikováno v:
Journal of Materials Chemistry B. 8:4016-4028
The cytotoxic and genotoxic effects of titanium dioxide (TiO2) nanoparticles when exposed to ultraviolet (UV) radiation, particularly wavelengths between 320-400 nm, has raised concern over their safe use in health and cosmetic related products such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ea5dcc28c6100ea9de177d281613ccb
https://doi.org/10.1039/d0tb00629g
https://doi.org/10.1039/d0tb00629g
Publikováno v:
Frontiers in molecular neuroscience. 15
Axons that are physically separated from their soma activate a series of signaling events that results in axonal self-destruction. A critical element of this signaling pathway is an intra-axonal calcium rise that occurs just prior to axonal fragmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bce5f919e91686803d43c67d4d0f2d
https://pubmed.ncbi.nlm.nih.gov/35370552
https://pubmed.ncbi.nlm.nih.gov/35370552