Zobrazeno 1 - 10
of 487
pro vyhledávání: '"Philip A, Lee"'
Autor:
Stephen G. Gonsalves, Leorey N. Saligan, Christopher M. Bergeron, Philip R. Lee, Kenneth W. Fishbein, Richard G. Spencer, Marta Zampino, Xinyi Sun, Jennifer Yeong-Shin Sheng, Vered Stearns, Michael Carducci, Luigi Ferrucci, Nada Lukkahatai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Physical impairments following cancer treatment have been linked with the toxic effects of these treatments on muscle mass and strength, through their deleterious effects on skeletal muscle mitochondrial oxidative capacity. Accordingly, we d
Externí odkaz:
https://doaj.org/article/9a93988e21354dae911d216638a56ee3
Autor:
Qu Tian, Philip R. Lee, Qi Yang, Anne Z. Moore, Bennett A. Landman, Susan M. Resnick, Luigi Ferrucci
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 138-148 (2024)
Abstract Background Mitochondrial dysfunction may contribute to brain and muscle health through inflammation or fat infiltration in the muscle, both of which are associated with cognitive function and mobility. We aimed to examine the association bet
Externí odkaz:
https://doaj.org/article/7029d685323c402b8766e254cc90e490
Autor:
Khushbu J. Patel, David Yang, John R. Best, Colleen Chambers, Philip E. Lee, Alexandre Henri‐Bhargava, Clark R. Funnell, Dean J. Foti, Jacqueline A. Pettersen, Howard H. Feldman, Haakon B. Nygaard, Ging‐Yuek R. Hsiung, Mari L. DeMarco
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION In the Investigating the Impact of Alzheimer's Disease Diagnostics in British Columbia (IMPACT‐AD BC) study, we aimed to understand how Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker testing—used in medical car
Externí odkaz:
https://doaj.org/article/0b3ef9451f9848b3a2c74e5b3e057d1f
Autor:
Chaofeng Lou, Hongbin Yang, Hua Deng, Mengting Huang, Weihua Li, Guixia Liu, Philip W. Lee, Yun Tang
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Chemical mutagenicity is a serious issue that needs to be addressed in early drug discovery. Over a long period of time, medicinal chemists have manually summarized a series of empirical rules for the optimization of chemical mutagenicity. H
Externí odkaz:
https://doaj.org/article/ab66073423da40079716e4a89cc25c52
Autor:
Brian T. Chung, Yaewon Kim, Jeremy W. Gordon, Hsin-Yu Chen, Adam W. Autry, Philip M. Lee, Jasmine Y. Hu, Chou T. Tan, Chris Suszczynski, Susan M. Chang, Javier E. Villanueva-Meyer, Robert A. Bok, Peder E.Z. Larson, Duan Xu, Yan Li, Daniel B. Vigneron
Publikováno v:
NeuroImage, Vol 280, Iss , Pp 120350- (2023)
Hyperpolarized (HP) 13C Magnetic Resonance Imaging (MRI) was applied for the first time to image and quantify the uptake and metabolism of [2–13C]pyruvate in the human brain to provide new metabolic information on cerebral energy metabolism. HP [2
Externí odkaz:
https://doaj.org/article/80b16af2de2f411fa0d9596665bfcda9
Autor:
Nicholas F G Chen, Chrispin Chaguza, Luc Gagne, Matthew Doucette, Sandra Smole, Erika Buzby, Joshua Hall, Stephanie Ash, Rachel Harrington, Seana Cofsky, Selina Clancy, Curtis J Kapsak, Joel Sevinsky, Kevin Libuit, Daniel J Park, Peera Hemarajata, Jacob M Garrigues, Nicole M Green, Sean Sierra-Patev, Kristin Carpenter-Azevedo, Richard C Huard, Claire Pearson, Kutluhan Incekara, Christina Nishimura, Jian Ping Huang, Emily Gagnon, Ethan Reever, Jafar Razeq, Anthony Muyombwe, Vítor Borges, Rita Ferreira, Daniel Sobral, Silvia Duarte, Daniela Santos, Luís Vieira, João Paulo Gomes, Carly Aquino, Isabella M Savino, Karinda Felton, Moneeb Bajwa, Nyjil Hayward, Holly Miller, Allison Naumann, Ria Allman, Neel Greer, Amary Fall, Heba H Mostafa, Martin P McHugh, Daniel M Maloney, Rebecca Dewar, Juliet Kenicer, Abby Parker, Katharine Mathers, Jonathan Wild, Seb Cotton, Kate E Templeton, George Churchwell, Philip A Lee, Maria Pedrosa, Brenna McGruder, Sarah Schmedes, Matthew R Plumb, Xiong Wang, Regina Bones Barcellos, Fernanda M S Godinho, Richard Steiner Salvato, Aimee Ceniseros, Mallery I Breban, Nathan D Grubaugh, Glen R Gallagher, Chantal B F Vogels
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002151 (2023)
The 2022 multicountry mpox outbreak concurrent with the ongoing Coronavirus Disease 2019 (COVID-19) pandemic further highlighted the need for genomic surveillance and rapid pathogen whole-genome sequencing. While metagenomic sequencing approaches hav
Externí odkaz:
https://doaj.org/article/f6624948d6784e6da2c1bd198855dab0
Publikováno v:
Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract UDP-glucuronosyltransferases (UGTs) have gained increasing attention as they play important roles in the phase II metabolism of drugs. Due to the time-consuming process and high cost of experimental approaches to identify the metabolic fate
Externí odkaz:
https://doaj.org/article/5985e5343f9b4bc0a22e6d73152296bd
Autor:
Denise H. Daudelin, Laura E. Peterson, Lisa C. Welch, Redonna Chandler, Mridu Pandey, Farzad Noubary, Philip L. Lee, Harry P. Selker
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 16-21 (2020)
The Clinical and Translational Science Award (CTSA) Consortium and the National Center for Advancing Translational Science (NCATS) undertook a Common Metrics Initiative to improve research processes across the national CTSA Consortium. This was imple
Externí odkaz:
https://doaj.org/article/7988cbd9ce2e46efb5614a3367406e6f
Autor:
Philip, Tracey Lee-Ann
The study aimed to explore women entrepreneurs’ experiences using social capital to develop their manufacturing businesses. Social capital has apparent benefits for developing women-owned businesses. The manufacturing sector has traditionally been
Externí odkaz:
http://hdl.handle.net/2263/81679
Publikováno v:
Journal of Neurosurgery. :1-6
OBJECTIVE The stereoelectroencephalography (SEEG) procedure provides a unique 3D overview of the seizure-onset zone. Although the success of SEEG relies on the accuracy of depth electrode implantation, few studies have investigated how different impl