Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Philip A, Gruppuso"'
Autor:
Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2356-2379 (2023)
Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity‐dependent labeling (PDL) with biotin follo
Externí odkaz:
https://doaj.org/article/9feb2424ca384d45925ebb57c2e9eae4
Autor:
John C. Santiago, Joan M. Boylan, Faye A. Lemieux, Philip A. Gruppuso, Jennifer A. Sanders, David M. Rand
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background In addition to their well characterized role in cellular energy production, new evidence has revealed the involvement of mitochondria in diverse signaling pathways that regulate a broad array of cellular functions. The mitochondri
Externí odkaz:
https://doaj.org/article/64f354fa81d643da9c7e4dff588f3ae6
Autor:
Anna Chorzalska, Nagib Ahsan, R. Shyama Prasad Rao, Karim Roder, Xiaoqing Yu, John Morgan, Alexander Tepper, Steven Hines, Peng Zhang, Diana O. Treaba, Ting C. Zhao, Adam J. Olszewski, John L. Reagan, Olin Liang, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 630-647 (2018)
The introduction of tyrosine kinase inhibitors (TKI) has transformed chronic myeloid leukemia (CML) into a chronic disease with long‐term survival exceeding 85%. However, resistance of CML stem cells to TKI may contribute to the 50% relapse rate ob
Externí odkaz:
https://doaj.org/article/61e7c5610dee4650acd0483ee9489b8a
Publikováno v:
Obstetrics & Gynecology. 140:408-411
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66766c445edf81a48ca8cb446065dc15
https://doi.org/10.1097/aog.0000000000004893
https://doi.org/10.1097/aog.0000000000004893
Autor:
Juanita K Hodax, Jose Bernardo Quintos, Philip A Gruppuso, Qian Chen, Salomi Desai, Chathuraka T Jayasuriya
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218399 (2019)
Aggrecan is an integral component of the extracellular matrix in cartilaginous tissues, including the growth plate. Heterozygous defects in the aggrecan gene have been identified as a cause of autosomal dominant short stature, bone age acceleration,
Externí odkaz:
https://doaj.org/article/2b0e7354271d45abb5cfad1087ca862c
Autor:
Valerie Zabala, Joan M Boylan, Paul Thevenot, Anderson Frank, Dewahar Senthoor, Varun Iyengar, Hannah Kim, Ari Cohen, Philip A Gruppuso, Jennifer A Sanders
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0227038 (2019)
There are few effective targeted strategies to reduce hepatic ischemia-reperfusion (IR) injury, a contributor to poor outcomes in liver transplantation recipients. It has been proposed that IR injury is driven by the generation of reactive oxygen spe
Externí odkaz:
https://doaj.org/article/12b5b00b6c6e468d98366405ff82160d
Autor:
Eli Y. Adashi, Philip A. Gruppuso
Publikováno v:
Mayo Clinic Proceedings. 97:1771-1773
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81163d4118cf8724b654fab53e233fd4
https://doi.org/10.1016/j.mayocp.2022.07.002
https://doi.org/10.1016/j.mayocp.2022.07.002
Autor:
Philip A Gruppuso, Joan M Boylan, Valerie Zabala, Nicola Neretti, Nebiyu A Abshiru, Jacek W Sikora, Emma H Doud, Jeannie M Camarillo, Paul M Thomas, Neil L Kelleher, Jennifer A Sanders
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203351 (2018)
Chromatin structure, a key contributor to the regulation of gene expression, is modulated by a broad array of histone post-translational modifications (PTMs). Taken together, these "histone marks" comprise what is often referred to as the "histone co
Externí odkaz:
https://doaj.org/article/1caaee12c994468fb5449398614069e4
Publikováno v:
Medical Education Online, Vol 20, Iss 0, Pp 1-8 (2015)
Problem: Programs that encourage scholarly activities beyond the core curriculum and traditional biomedical research are now commonplace among US medical schools. Few studies have generated outcome data for these programs. The goal of the present stu
Externí odkaz:
https://doaj.org/article/fdf1d0d92f5f4edc943b5a20871ef39c
Autor:
Briana Garcia, Heather Francois-Vaughan, Omobola Onikoyi, Stefan Kostadinov, Monique E. De Paepe, Philip A. Gruppuso, Jennifer A. Sanders
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 12, Pp 2685-2691 (2014)
Obesity during childhood and beyond may have its origins during fetal or early postnatal life. At present, there are no suitable in vivo experimental models to study factors that modulate or perturb human fetal white adipose tissue (WAT) expansion, r
Externí odkaz:
https://doaj.org/article/d50cb9754ec946e68337b27ec51d6927