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In-vitro and in-vivo evaluation of taste-masked cetirizine hydrochloride formulated in oral lyophilisates

Autor: Leon Paul Grother, Philip Axe, Joerg Breitkreutz, Maren Preis

Publikováno v: International Journal of Pharmaceutics. 491:8-16

The use of solid oral dosage forms is typically favored with regard to stability and ease of administration. The aim of this study was to investigate whether cyclodextrins (CD) or ion exchange resins (IER) could be used to taste-mask cetirizine HCl w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea0133ff12580bd9bb07d9669125058
https://doi.org/10.1016/j.ijpharm.2015.06.002

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Getting the measure of eutrophication in the Baltic Sea: towards improved assessment principles and methods

Autor: Ulrich Claussen, Hermanni Kaartokallio, Maria Laamanen, Alf Norkko, Seppo Knuuttila, Samuli Korpinen, Jacob Carstensen, Vivi Fleming-Lehtinen, Anna Villnäs, Jesper H. Andersen, Philip Axe, Elzbieta Lysiak-Pastuszak, Georg Martin, Guenther Nausch, Aiste Kubiliute, Flemming Møhlenberg, Ciarán Murray, Marko Järvinen, Hermanni Backer

Publikováno v: Andersen, J, Axe, P, Backer, H, Carstensen, J, Claussen, U, Fleming-Lehtinen, V, Järvinen, M, Kaartokallio, H, Knuuttila, S, Korpinen, S, Kubiliute, A, Laamanen, M, Lysiak-Pastuszak, E, Martin, G, Murray, C, Møhlenberg, F, Nausch, G, Norkko, A & Villnäs, A 2011, ' Getting the measure of eutrophication in the Baltic Sea: towards improved assessment principles and methods ', Biogeochemistry, vol. 106, pp. 137-156 . https://doi.org/10.1007/s10533-010-9508-4

The eutrophication status of the entire Baltic Sea is classified using a multi-metric indicator- based assessment tool. A total of 189 areas are assessed using indicators where information on reference conditions (RefCon), and acceptable devi- ation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2ae6faa76a74499bfa77c4713b1a9d
https://doi.org/10.1007/s10533-010-9508-4

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Reorganization of a large marine ecosystem due to atmospheric and anthropogenic pressure: a discontinuous regime shift in the Central Baltic Sea

Autor: Bärbel Müller-Karulis, Philip Axe, Rabea Diekmann, Georgs Kornilovs, Christian Möllmann, Maris Plikshs

Publikováno v: Global Change Biology. 15:1377-1393

Marine ecosystems such as the Baltic Sea are currently under strong atmospheric and anthropogenic pressure. Besides natural and human-induced changes in climate, major anthropogenic drivers such as overfishing and anthropogenic eutrophication are sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa06d6c9849622e9e980a8b261d69afc
https://doi.org/10.1111/j.1365-2486.2008.01814.x

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Temporal development of coastal ecosystems in the Baltic Sea over the past two decades

Autor: Lena Bergström, Anna Gårdmark, Didzis Ustups, Heikki Peltonen, Ivars Putnis, Arno Põllumäe, Pavel Gasyukov, Bärbel Müller-Karulis, Philip Axe, Grete E. Dinesen, Outi Heikinheimo, Lena Szymanek, Jens Olsson, Henn Ojaveer, Mart Simm, Maciej T. Tomczak

Publikováno v: Olsson, J, Tomczak, M, Ojaveer, H, Gårdmark, A, Põllumäe, A, Muller-Karulis, B, Ustups, D, Dinesen, G E, Peltonen, H, Putnis, I, Szymanek, L, Simm, M, Heikinheimo, O, Gasyukov, P, Axe, P & Bergström, L 2015, ' Temporal development of coastal ecosystems in the Baltic Sea over the past two decades ', ICES Journal of Marine Science, vol. 72, no. 9, pp. 2539-2548 . https://doi.org/10.1093/icesjms/fsv143

Swedish Agency for Water Management, Gothenburg, Sweden*Corresponding author: tel: +46 10 478 41 44; e-mail: jens.olsson@slu.seOlsson,J.,Tomczak,M.T.,Ojaveer,H.,Ga˚rdmark,A.,Po˜lluma¨e,A.,Mu¨ller-Karulis,B.,Ustups,D.,Dinesen,G.E.,Peltonen,H.,Putn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983d03a13aa1cafd3c0ab83902fbcbff
https://orbit.dtu.dk/en/publications/c6fa1369-3261-429b-a623-b76518e8e82c

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Hypoxia is increasing in the coastal zone of the Baltic Sea

Autor: Juris Aigars, Tatjana Eremina, Sunhild Wilhelms, Jakob Walve, Lovisa Zillén, Miguel Rodriguez Medina, Christer Lannegren, Philip Axe, Elzbieta Lysiak-Pastuszak, Britt-Marie Haahti, Nijole Remeikaite-Nikiene, Daniel J. Conley, A. A. Maximov, Jonne Kotta, Erik Bonsdorff, Ulf Larsson, Jacob Carstensen, Christoph Humborg, Per Jönsson

Publikováno v: Conley, D J, Carstensen, J, Aigars, J, Axe, P, Bonsdorff, E, Eremina, T, Haahti, B-M, Humborg, C, Jonsson, P, Kotta, J, Lännegren, C, Larsson, U, Maximov, A, Medina, M R, Lysiak-Pastuszak, E, Remeikaite-Nikiene, N, Walve, J, Wilhelms, S & Zillén, L 2011, ' Hypoxia is increasing in the coastal zone of the Baltic Sea ', Environmental Science & Technology (Washington), vol. 45, pp. 6777-6783 . https://doi.org/10.1021/es201212r
Environmental Science & Technology

Hypoxia is a well-described phenomenon in the offshore waters of the Baltic Sea with both the spatial extent and intensity of hypoxia known to have increased due to anthropogenic eutrophication, however, an unknown amount of hypoxia is present in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c7aae7b190a1d151403fc03eb4ce5f
https://pure.au.dk/portal/da/publications/hypoxia-is-increasing-in-the-coastal-zone-of-the-baltic-sea(2cf95071-630b-4179-b01a-0d0286e4aaed).html

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A pyridinium cation-π interaction sensor for the fluorescent detection of alkyl halides

Autor: Ysé Nonne, John S. Fossey, Louise Male, Shinji Yamada, Philip Axe, Souad A. Elfeky, Kabir Ahmed, Claire Amiable, Tony D. James, Steven D. Bull, Wenbo Chen

Publikováno v: Chemical communications (Cambridge, England). 47(1)

N-Alkylation of a novel pyridine sensor results in pyridinium salts whose conformations are stabilised by pyridinium cation–π interactions resulting in a fluorescent response that can be used to sense the presence of alkylating agents in solution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3eb8789b9408fd5dd4315e493297fb
https://pubmed.ncbi.nlm.nih.gov/20601994

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An enantiopure pseudo-C3-symmetric titanium triflate with propeller-like chirality as a catalyst for asymmetric sulfoxidation reactions

Autor: Matthew G. Davidson, Steven D. Bull, John E. Warren, Philip Axe, Diane E. J. E. Robinson, William L. Mitchell, Matthew D. Jones

Publikováno v: Dalton transactions (Cambridge, England : 2003). (46)

A chiral pseudo-C(3)-symmetric titanium triflate that employs the point chirality of a single stereogenic centre to control the propeller chirality of its aryl rings has been used to catalyse an asymmetric sulfoxidation reaction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ba2eeddc810454611bb6e98f6ef269
https://pubmed.ncbi.nlm.nih.gov/19921048

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A simple method for confidence rating of eutrophication status classifications

Autor: Hermanni Kaartokallio, Ciarán Murray, Jesper H. Andersen, Philip Axe, Jarle Molvær

Publikováno v: Marine pollution bulletin. 60(6)

We report the development of a methodology for assessing confidence in ecological status classifications. The method presented here can be considered as a secondary assessment, supporting the primary assessment of eutrophication or ecological status.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8c11de632dffb2bb8b21561dc12122
https://pubmed.ncbi.nlm.nih.gov/20381096

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