Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Philip, Kantoff"'
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
Supplementary Figure 1. Mutation rates by cohort. Supplementary Figure 2. ERCC2 mutations. Supplementary Figure 3. ERCC2 mutation status and overall survival. Supplementary Figure 4. ERCC2 mutations occur in highly conserved regions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8792ad3b88aeda063804861e8c6f6416
https://doi.org/10.1158/2159-8290.22530441.v1
https://doi.org/10.1158/2159-8290.22530441.v1
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
Significantly altered genes in clinical subsets. MutSigCV ranked lists for significantly mutated genes in the non-responders only (n = 25), the responders only (n = 25), and the ERCC2WT responders only (n = 16).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d07307f4a0dcf996e6c43fbcf71ea9
https://doi.org/10.1158/2159-8290.22530429
https://doi.org/10.1158/2159-8290.22530429
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
All alterations in responders and non-responders. All somatic mutations and short insertion/deletions are listed, with additional annotations regarding genomic coordinates, protein change, allelic fractions, and validation status (if available).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40133a4082187bb738360e273059e22
https://doi.org/10.1158/2159-8290.22530435.v1
https://doi.org/10.1158/2159-8290.22530435.v1
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
Damaging scores for alterations. This table shows the damaging scores (Methods) for nonsynonymous alterations (missense, nonsense, splice site, frame shift) studied in this cohort. The damaging score was derived as follows: missense mutations were sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91f1091a20cb4acd7244665f0b3b289
https://doi.org/10.1158/2159-8290.22530426.v1
https://doi.org/10.1158/2159-8290.22530426.v1
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
Treatment information and sequencing metrics for all patients The treatment information and raw sequencing metrics, including mean target coverage, for each case is listed here. In addition, the mutation rate data referred to in the Results and repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334e7c5c1a23aa228e4f0a2210a13b46
https://doi.org/10.1158/2159-8290.22530438.v1
https://doi.org/10.1158/2159-8290.22530438.v1
Autor:
Jonathan E. Rosenberg, Levi A. Garraway, Alan D'Andrea, Stacey Gabriel, David B. Solit, Dean F. Bajorin, Toni K. Choueiri, Bernard H. Bochner, Philip Kantoff, Gad Getz, Michael Lawrence, Jesse Boehm, Victor Reuter, Justine A. Barletta, Sabina Signoretti, Angela Qu, Deborah Farlow, Namrata Gupta, Samira Bahl, Richard Bambury, Elizabeth A. Guancial, Jaegil Kim, Ilana Garcia-Grossman, John Sfakianos, Kevin W. O'Connor, Gregory V. Kryukov, Irina Ostrovnaya, Cong Zhu, Hikmat Al-Ahmadie, Nikhil Wagle, Gopa Iyer, Philip Kim, Kent W. Mouw, Eliezer M. Van Allen
Selective alteration enrichment. This table shows the results of applying Fisher's Exact Test to a tabulated set of predicted damaging somatically altered genes in responders compared to non-responders. A Benjamini-Hochberg/FDR q-value is reported fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686145a458813471867ea00283df35b4
https://doi.org/10.1158/2159-8290.22530423
https://doi.org/10.1158/2159-8290.22530423
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a1d5ad71950008144484ceac754a37
https://doi.org/10.1158/1078-0432.c.6524298
https://doi.org/10.1158/1078-0432.c.6524298
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Supplementary Methods, Table S1, Figures S1-7. Methods for quantitative multiplex proteomics imaging (QMPI) Clinical studies: Statistical plan Table S1. Clinical Validation Study. Comparison of Predictive Value of the 8-Biomarker Assay for Favorable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a775876007c847964815ceef0082305
https://doi.org/10.1158/1078-0432.22459749
https://doi.org/10.1158/1078-0432.22459749
Autor:
Neil J Shah, Vaibhav G Patel, Xiaobo Zhong, Luis Pina, Jessica E Hawley, Emily Lin, Benjamin A Gartrell, Victor Adorno Febles, David R Wise, Qian Qin, George Mellgard, Himanshu Joshi, Jones T Nauseef, David A Green, Panagiotis J Vlachostergios, Daniel H Kwon, Franklin Huang, Bobby Liaw, Scott Tagawa, Philip Kantoff, Michael J Morris, William K Oh
Publikováno v:
JNCI cancer spectrum, vol 6, iss 3
Background TMPRSS2, a cell surface protease regulated by androgens and commonly upregulated in prostate cancer (PCa), is a necessary component for SARS-CoV-2 viral entry into respiratory epithelial cells. Previous reports suggested a lower risk of SA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8587fb98b8dc993f295884242068e9a
https://doi.org/10.1093/jncics/pkac035
https://doi.org/10.1093/jncics/pkac035
Autor:
José Luis Ferreira Duque, Kevin R. Loughlin, Rosalyn M. Adam, Philip Kantoff, Eduardo Mazzucchi, Michael R. Freeman
Publikováno v:
Clinics, Vol 61, Iss 5, Pp 401-408 (2006)
PURPOSE: This study focused on circulating levels of vascular endothelial growth factor in patients with prostate cancer compared to a normal population. METHODS: We analyzed 26 normal individuals and 80 patients with prostate cancer. Blood was drawn
Externí odkaz:
https://doaj.org/article/7901235cb4894cff85d7eedd0eee3cdd