Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Philip, Eaton"'
Autor:
Gerd Heusch, Ioanna Andreadou, Robert Bell, Edoardo Bertero, Hans-Erik Botker, Sean M. Davidson, James Downey, Philip Eaton, Peter Ferdinandy, Bernard J. Gersh, Mauro Giacca, Derek J. Hausenloy, Borja Ibanez, Thomas Krieg, Christoph Maack, Rainer Schulz, Frank Sellke, Ajay M. Shah, Holger Thiele, Derek M. Yellon, Fabio Di Lisa
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102894- (2023)
The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond that by rapid reperfusion
Externí odkaz:
https://doaj.org/article/0fa5d92cdebd454588eef18a999eac76
Autor:
Raphael F. Queiroz, Christopher P. Stanley, Kathryn Wolhuter, Stephanie M. Y. Kong, Ragul Rajivan, Naomi McKinnon, Giang T. H. Nguyen, Antonella Roveri, Sebastian Guttzeit, Philip Eaton, William A. Donald, Fulvio Ursini, Christine C. Winterbourn, Anita Ayer, Roland Stocker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
A major question in redox signaling is how H2O2 oxidizes target protein thiols in the presence of glutathione peroxidases and peroxiredoxins. We reveal signaling by H2O2 via its enzymatic conversion to an alkyl hydroperoxide that stereo-specifically
Externí odkaz:
https://doaj.org/article/16b1acb3e2684793a89d03d6d3dc92b4
Autor:
Alexis Olsho, Trevor I. Smith, Philip Eaton, Charlotte Zimmerman, Andrew Boudreaux, Suzanne White Brahmia
Publikováno v:
Physical Review Physics Education Research, Vol 19, Iss 1, p 013101 (2023)
We developed the Physics Inventory of Quantitative Literacy (PIQL) to assess students’ quantitative reasoning in introductory physics contexts. The PIQL includes several “multiple-choice-multiple-response” (MCMR) items (i.e., multiple-choice qu
Externí odkaz:
https://doaj.org/article/9f75f0514be543d2a5569b17f88f7755
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102155- (2021)
The cellular effects of hydrogen sulfide (H2S) signaling may be partially mediated by the formation of alkyl persulfides from thiols, such as glutathione and protein cysteine residues. Persulfides are potent nucleophiles and reductants and therefore
Externí odkaz:
https://doaj.org/article/ae13c340f5d74bcb98d687fc0772327f
Autor:
M. M. Towhidul Islam, Daniel Tarnowski, Min Zhang, Maximilian Trum, Simon Lebek, Julian Mustroph, Henriette Daniel, Johanna Moellencamp, Steffen Pabel, Samuel Sossalla, Ali El‐Armouche, Viacheslav O. Nikolaev, Ajay M. Shah, Philip Eaton, Lars S. Maier, Can Martin Sag, Stefan Wagner
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 19 (2021)
Background PKARIα (protein kinase A type I‐α regulatory subunit) is redox‐active independent of its physiologic agonist cAMP. However, it is unknown whether this alternative mechanism of PKARIα activation may be of relevance to cardiac excitat
Externí odkaz:
https://doaj.org/article/c41f9e0efc2e43b39a82934e6734a4e4
Autor:
Rebecca L. Charles, Giancarlo Abis, Beatriz F. Fernandez, Sebastian Guttzeit, Roberto Buccafusca, Maria R. Conte, Philip Eaton
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102107- (2021)
Soluble epoxide hydrolase (sEH), an enzyme that broadly regulates the cardiovascular system, hydrolyses epoxyeicosatrienoic acids (EETs) to their corresponding dihydroxyeicosatrienoic acids (DHETs). We previously showed that endogenous lipid electrop
Externí odkaz:
https://doaj.org/article/6c4dfd7f8fb5403ba6f81bf411240c08
Autor:
Rebecca Charles, Philip Eaton
Publikováno v:
Cells, Vol 11, Iss 12, p 1932 (2022)
Cell responses to changes in their redox state are significantly mediated by reversible oxido-reductive post-translational modifications of proteins, potentially altering their activities or interactions. These modifications are important for the hom
Externí odkaz:
https://doaj.org/article/8ee9058cf9ee4bb4b0ef8ed11623062a
Publikováno v:
World Journal of Cardiovascular Diseases. 13:7-20
Publikováno v:
World Journal of Cardiovascular Diseases. 13:236-242
Publikováno v:
The American Journal of Medicine. 136:408-410