Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Phileno Pinge Filho"'
Autor:
Sergio M. Borghi, Aparecida D. Malvezi, Maria Isabel Lovo-Martins, Victor Fattori, Tiago H. Zaninelli, Mariana M. Bertozzi, Camila R. Ferraz, Thiago M. Cunha, Rubia Casagrande, Marli C. Martins-Pinge, Phileno Pinge-Filho, Waldiceu A. Verri, Jr.
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100897- (2024)
Chagas’ disease is a life-threatening condition caused by Trypanosoma cruzi. Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by T. cruzi can occur in the acute phase
Externí odkaz:
https://doaj.org/article/a1899c10dfa349ae86851ae383fd1dea
Autor:
Terezinha de Jesus Faria, Mariana Carrara Cafêu, Gisele Akiyoshi, Dalva Trevisan Ferreira, Olívio Fernandes Galão, César Cornélio Andrei, Phileno Pinge Filho, Manoel Ronaldo Carvalho Paiva, Aneli de Melo Barbosa, Raimundo Braz-Filho
Publikováno v:
Química Nova, Vol 30, Iss 3, Pp 525-527 (2007)
In vitro bioassays with leave extracts of Erythrina speciosa showed promising activity against Trypanosoma cruzi. From the flowers of E. speciosa two alkaloids were isolated: erysotrine and erythartine. The leaves furnished one alkaloid, nororientali
Externí odkaz:
https://doaj.org/article/dd89b9477b3d4d9d98affb00520f015b
Autor:
Gabriella Maria Andriani, Lais Fernanda de Almeida Spoladori, Marciéli Fabris, Priscila Goes Camargo, Patrícia Morais Lopes Pereira, Jussevania Pereira Santos, Guilherme Bartolomeu-Gonçalves, Lais Alonso, Cesar Armando Contreras Lancheros, Antonio Alonso, Celso Vataru Nakamura, Fernando Macedo, Phileno Pinge-Filho, Lucy Megumi Yamauchi, Marcelle de Lima Ferreira Bispo, Eliandro Reis Tavares, Sueli Fumie Yamada-Ogatta
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionCryptococcus neoformans is one of the leading causes of invasive fungal infections worldwide. Cryptococcal meningoencephalitis is the main challenge of antifungal therapy due to high morbidity and mortality rates, especially in low- and m
Externí odkaz:
https://doaj.org/article/fa9ac02878f4489fae440abbd9a51c20
Autor:
Patrícia Morais Lopes Pereira, Bruna Terci Fernandes, Vitória Ribeiro dos Santos, Weslei Roberto Correia Cabral, Maria Isabel Lovo-Martins, Lais Alonso, César Armando Contreras Lancheros, Jéssica Carreira de Paula, Priscila Goes Camargo, Helena Tiemi Suzukawa, Antônio Alonso, Fernando Macedo, Celso Vataru Nakamura, Eliandro Reis Tavares, Marcelle de Lima Ferreira Bispo, Lucy Megumi Yamauchi, Phileno Pinge-Filho, Sueli Fumie Yamada-Ogatta
Publikováno v:
Pathogens, Vol 12, Iss 8, p 1012 (2023)
For decades, only two nitroheterocyclic drugs have been used as therapeutic agents for Chagas disease. However, these drugs present limited effectiveness during the chronic phase, possess unfavorable pharmacokinetic properties, and induce severe adve
Externí odkaz:
https://doaj.org/article/cd8105990eb3421886d57a95c9d6cb19
Autor:
Vera Lúcia Hideko Tatakihara, Aparecida Donizette Malvezi, Rito Santo Pereira, Bruno Fernando Cruz Lucchetti, Lucas Felipe Dos Santos, Rubens Cecchini, Lucy Megumi Yamauchi, Sueli Fumie Yamada-Ogatta, Katrina M. Miranda, Waldiceu A. Verri, Marli Cardoso Martins-Pinge, Phileno Pinge-Filho
Publikováno v:
Pathogens, Vol 12, Iss 8, p 1063 (2023)
Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical disease prevalent in Latin America. Infected patients are treated to eliminate the parasite, reduce the cardiomyopathy risk, and interrupt the disease transmission cycle. The W
Externí odkaz:
https://doaj.org/article/6f4676c9be2945059b5b9683424621b8
Autor:
Laís Fernanda de Almeida Spoladori, Gabriella Maria Andriani, Isabela Madeira de Castro, Helena Tiemi Suzukawa, Ana Carolina Ramos Gimenes, Guilherme Bartolomeu-Gonçalves, Kelly Ishida, Gerson Nakazato, Phileno Pinge-Filho, Rayanne Regina Beltrame Machado, Celso Vataru Nakamura, Galdino Andrade, Eliandro Reis Tavares, Lucy Megumi Yamauchi, Sueli Fumie Yamada-Ogatta
Publikováno v:
Antibiotics, Vol 12, Iss 5, p 861 (2023)
Candida auris has been found to be a persistent colonizer of human skin and a successful pathogen capable of causing potentially fatal infection, especially in immunocompromised individuals. This fungal species is usually resistant to most antifungal
Externí odkaz:
https://doaj.org/article/9540526405034ac1b56ff3e43c94376c
Autor:
Sergio M. Borghi, Victor Fattori, Felipe A. Pinho-Ribeiro, Talita P. Domiciano, Milena M. Miranda-Sapla, Tiago H. Zaninelli, Rubia Casagrande, Phileno Pinge-Filho, Wander R. Pavanelli, Jose C. Alves-Filho, Fernando Q. Cunha, Thiago M. Cunha, Waldiceu A. Verri
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-23 (2019)
Abstract Background The cellular and molecular pathophysiological mecha\nisms of pain processing in neglected parasitic infections such as leishmaniasis remain unknown. The present study evaluated the participation of spinal cord glial cells in the p
Externí odkaz:
https://doaj.org/article/1444f579f42046eebfc3a07041fec0fc
Autor:
Lorena de Jager, Camila Borecki Vidigal, Blenda Hyedra de Campos, Gabriela Souza Reginato, Lorena Maria Fernandes, Deborah Ariza, Carolina Matias Higashi-Mckeown, Mariana Marques Bertozzi, Fernanda Soares Rasquel de Oliveira, Waldiceu Aparecido Verri Jr, Graziela Scalianti Ceravolo, Carlos César Crestani, Phileno Pinge-Filho, Marli Cardoso Martins-Pinge
Publikováno v:
Nitric Oxide. :49-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::277f944d683f2116bcf541924ce8b56c
https://doi.org/10.1016/j.niox.2023.04.003
https://doi.org/10.1016/j.niox.2023.04.003
Autor:
Sergio M. Borghi, Victor Fattori, Thacyana T. Carvalho, Vera L. H. Tatakihara, Tiago H. Zaninelli, Felipe A. Pinho-Ribeiro, Camila R. Ferraz, Larissa Staurengo-Ferrari, Rubia Casagrande, Wander R. Pavanelli, Fernando Q. Cunha, Thiago M. Cunha, Phileno Pinge-Filho, Waldiceu A. Verri
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The neglected tropical infirmity Chagas disease (CD) presents high mortality. Its etiological agent T. cruzi is transmitted by infected hematophagous insects. Symptoms of the acute phase of the infection include fever, fatigue, body aches, and headac
Externí odkaz:
https://doaj.org/article/6d64d561de114af8a0fc8fdb5b350c8b
Autor:
Natalia Veronez da Cunha, Fernanda Novi Cortegoso Lopes, Carolina Panis, Rubens Cecchini, Phileno Pinge-Filho, Marli Cardoso Martins-Pinge
Publikováno v:
Clinical and Experimental Hypertension, Vol 39, Iss 1, Pp 50-57 (2017)
It has been suggested that nitric oxide (NO) from iNOS source is involved in inflammation and oxidative stress, and hypertension in obese subjects involves an inflammatory process. However, no study evaluated the participation of iNOS inhibition on c
Externí odkaz:
https://doaj.org/article/8fd35505d787409fab07c772c5d3ffa1