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Autor:
Terry Hauser, Kristen G. Jordan, Yun-De Xiao, Patrick M. Lippiello, Merouane Bencherif, John W. James, Jason Speake, Sharon R. Letchworth, Jiahui Zhang, Mazurov Anatoly A, Phil S. Hammond, Katherine M. Van Dyke
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:813-823
Nicotinic α4β2* agonists are known to be effective in a variety of preclinical pain models, but the underlying mechanisms of analgesic action are not well-understood. In the present study, we characterized activation and desensitization properties