Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Phil N, Newsome"'
1
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance
Autor: Raluca Pais, Rachel Ostroff, Stephen Harrison, Lars Friis Mikkelsen, Elisabeth Erhardtsen, Sudha Shankar, Kimmo Porthan, Jérôme Boursier, Antonia Sinisi, Michael Kalutkiewicz, Sven Francque, Miljen Martic, Vanessa Pellegrinelli, Phil N. Newsome, Guido Hanauer, Hannele Yki-Järvinen, Rebecca Darlay, Joel Myers, Carla Yunis, Salvatore Petta, Mette Skalshøi Kjær, Pablo Ortiz, Ann K. Daly, James H. Clark, Dina Tiniakos, Yasaman Vali, Hadi Zafarmand, Matej Orešič, Maurizio Parola, Estelle Sandt, Lori L. Jennings, Matt Kelly, Tuulia Hyötyläinen, Detlef Schuppan, Céline Fournier, Chiara Rosso, Diane E. Shevell, Maria Manuela Tonini, Paul Hockings, Aidan McGlinchey, Salma Akhtar, Mette Juul Fisker, Morten A. Karsdal, Diane Whalley, Melissa R. Miller, Aldo Trylesinski, Mattias Ekstedt, Stefan Neubauer, Jeremy M. Palmer, Partho Sen, Michael Pavlides, Per Qvist, Isabel Fernández, Luca Miele, Fabio Marra, Stergios Kechagias, Richard Torstenson, Katherine Johnson, Jean-François Dufour, Elisabetta Bugianesi, M. Julia Brosnan, George V. Papatheodoridis, Kay M. Pepin, Daniel Guldager Kring Rasmussen, Henrik Landgren, Rachel Queen, Simon Cockell, Michael Allison, Patrick M.M. Bossuyt, Rocío Gallego-Durán, Christian Rosenquist, Leigh Alexander, Elizabeth Shumbayawonda, Michele Vacca, Antonio Vidal-Puig, David Wenn, Rémy Hanf, Oscar Millet, Michalina Zatorska, R. Myers, José M. Mato, Jenny Lee, Theresa Tuthill, James Twiss, Ramy Younes, Peter Leary, Lynda Doward, Kristy Wonders, Guruprasad P. Aithal, Sarah Charlton, Vlad Ratziu, Cecília M. P. Rodrigues, Christian Trautwein, Helena Cortez-Pinto, Gideon Ho, Matt J. Barter, Judith Ertle, Jörn M. Schattenberg, Maria-Magdalena Balp, Yang-Lin Liu, Clifford A. Brass, Olivier Govaere, Amalia Gastaldelli, Sergio Rodriguez Cuenca, Pierre Chaumat, Fiona Oakley, Luca Valenti, Simon J. Cockell, Saskia W.C. van Mil, Ferenc E. Mózes, Andreas Geier, Timothy Hardy, Pierre Bedossa, Andrea Dennis, Richard L. Ehman, Charlotte Erpicum, Karine Clément, Jeremy F. L. Cobbold, Christopher P. Day, Rajarshi Banerjee, Manuel Romero-Gómez, Quentin M. Anstee, Adriaan G. Holleboom, Heather J. Cordell, Kevin L. Duffin, Diana Julie Leeming
Publikováno v: JHEP Reports, 4(2):100409. Elsevier
JHEP Reports
JHEP Reports, Vol 4, Iss 2, Pp 100409-(2022)
JHEP reports 4(2), 100409 (2022). doi:10.1016/j.jhepr.2021.100409
Background & Aims Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods We profiled 2,083 ser
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c39a3a5921e0d464a7b2b93c40ef52c
https://pure.amc.nl/en/publications/increased-serum-mir193a5p-during-nonalcoholic-fatty-liver-disease-progression(bd6dd66c-d686-4b4d-be46-956a848f1f3b).html
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2
Prevalence of High-risk Nonalcoholic Steatohepatitis (NASH) in the United States: Results From NHANES 2017–2018
Autor: Eduardo Vilar-Gomez, Raj Vuppalanchi, Andrea Mladenovic, Niharika Samala, Samer Gawrieh, Phil N. Newsome, Naga Chalasani
Publikováno v: Clinical Gastroenterology and Hepatology. 21:115-124.e7
The population prevalence of high-risk non-alcoholic steatohepatitis (NASH), defined as nonalcoholic fatty liver disease activity score ≥4 and fibrosis stage ≥2, is unknown. The FibroScan-AST (FAST) score, calculated using liver stiffness measure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1196ff973853aea7773681c8a221f35a
https://doi.org/10.1016/j.cgh.2021.12.029
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4
Origin-Specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence Their Behavior After Infusion
Autor: Lozan, Sheriff, Asma, Alanazi, Lewis S C, Ward, Carl, Ward, Hafsa, Munir, Julie, Rayes, Mohammed, Alassiri, Steve P, Watson, Phil N, Newsome, G E, Rainger, Neena, Kalia, Jon, Frampton, Helen M, McGettrick, Gerard B, Nash
Publikováno v: Stem Cells (Dayton, Ohio)
We investigated the adhesive behavior of mesenchymal stem cells (MSC) in blood, which might influence their fate when infused as therapy. Isolated human bone marrow MSC (BMMSC) or umbilical cord MSC (UCMSC) adhered efficiently from flow to the matrix
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9e7fe9068268c68a25bb101f535b8dc1
https://pubmed.ncbi.nlm.nih.gov/29488279
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5
The Orphan liver Diseases
Autor: Phil N. Newsome, Reenam Khan
Publikováno v: In Clinical Practice ISBN: 9783319431253
A 46-year-old Caucasian male was referred to the gastroenterology clinic with abdominal distension and jaundice. His medical history included chronic obstructive pulmonary disease. He had a five pack-year smoking history and was a teetotaller. He had
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9477941ce59ed3f938a3bfc20baaabdd
https://doi.org/10.1007/978-3-319-43126-0_9
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8
Early nitisinone treatment reduces the need for liver transplantation in children with tyrosinaemia type 1 and improves post-transplant renal function
Autor: David C. Bartlett, Patrick J. McKiernan, C. Lloyd, Phil N. Newsome
Publikováno v: Journal of inherited metabolic disease. 37(5)
Tyrosinaemia type 1 (HT1) is a rare disorder of tyrosine metabolism leading to liver failure and hepatocellular carcinoma. Treatment previously consisted of dietary restriction and orthotopic liver transplantation (OLT) but was transformed by the int
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4a1b257bcec0094f050036134a7ccb
https://pubmed.ncbi.nlm.nih.gov/24515874
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9
Crosstalk between mesenchymal stem cells and endothelial cells leads to downregulation of cytokine-induced leukocyte recruitment
Autor: Phil N. Newsome, Jon Frampton, Gerard B. Nash, Helen M. McGettrick, G. Ed Rainger, N. Thin Luu, Christopher D. Buckley
Publikováno v: Stem cells (Dayton, Ohio). 31(12)
Mesenchymal stem cells (MSC) have immunomodulatory properties, but their effects on endothelial cells (EC) and recruitment of leukocytes are unknown. We cocultured human bone marrow-derived MSC with EC and found that MSC could downregulate adhesion o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf50f3eae50407796bbd224fc02fc9a
https://pubmed.ncbi.nlm.nih.gov/23939932
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10
Plasma succinylacetone is persistently raised after liver transplantation in tyrosinaemia type 1
Autor: Patrick J. McKiernan, Mary Anne Preece, Phil N. Newsome, Elisabeth Holme, David C. Bartlett, C. Lloyd
Publikováno v: Journal of inherited metabolic disease. 36(1)
Tyrosinaemia type 1 (HT1) is a rare disorder leading to accumulation of toxic metabolites such as succinylacetone (SA) and a high risk of hepatocellular carcinoma. Children with HT1 traditionally required liver transplantation (OLT) and while the nee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48af63f94c28b1a02bb49bf4c59e17b4
https://pubmed.ncbi.nlm.nih.gov/22456946
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