Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Phi T. Nguyen"'
Autor:
Elena Carazo-Arias, Phi T. Nguyen, Marley Kass, Hyun Jung Jee, Katherine M. Nautiyal, Valerie Magalong, Lilian Coie, Valentine Andreu, Mark M. Gergues, Huzefa Khalil, Huda Akil, Danusa Mar Arcego, Michael Meaney, Christoph Anacker, Benjamin A. Samuels, John E. Pintar, Irina Morozova, Sergey Kalachikov, Rene Hen
Publikováno v:
Biological Psychiatry. 92:952-963
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e439cd1c373d9f224f32488ab6afa0
https://doi.org/10.1016/j.biopsych.2022.05.030
https://doi.org/10.1016/j.biopsych.2022.05.030
Autor:
Aimee W. Kao, Austin L Wang, Anand Patwardhan, Michael Grabe, Phi T. Nguyen, Kean-Hooi Ang, Anna V. Molofsky, Carolina Alquezar, Michelle R. Arkin, Marcus Y. Chin, Mackenzie Welch
Publikováno v:
ACS Sensors
ACS sensors, vol 6, iss 6
ACS sensors, vol 6, iss 6
Lysosomes are important sites for macromolecular degradation, defined by an acidic lumenal pH of ∼4.5. To better understand lysosomal pH, we designed a novel, genetically encoded, fluorescent protein (FP)-based pH biosensor called Fluorescence Indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2415b35c8d9c812672f8372fce4396ee
https://doi.org/10.1021/acssensors.0c02318
https://doi.org/10.1021/acssensors.0c02318
Autor:
Leah C, Dorman, Phi T, Nguyen, Caroline C, Escoubas, Ilia D, Vainchtein, Yinghong, Xiao, Peter V, Lidsky, Haruna, Nakajo, Nicholas J, Silva, Christian, Lagares-Linares, Ellen Y, Wang, Sunrae E, Taloma, Beatriz, Cuevas, Hiromi, Nakao-Inoue, Brianna M, Rivera, Bjoern, Schwer, Carlo, Condello, Raul, Andino, Tomasz J, Nowakowski, Anna V, Molofsky
Publikováno v:
bioRxiv : the preprint server for biology.
Microglia, the innate immune cells of the brain, are exquisitely sensitive to dynamic changes in the neural environment. Using single cell RNA sequencing of the postnatal somatosensory cortex during topographic remapping, we identified a type I inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77fff49b25e7b36499cbc1dc125ab87a
https://pubmed.ncbi.nlm.nih.gov/35233577
https://pubmed.ncbi.nlm.nih.gov/35233577
An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
Autor:
Nicholas Stevers, Tanvi Joshi, Kristle Garcia, Hani Goodarzi, Hun-Way Hwang, Sohit Miglani, Andrei Goga, Phi T. Nguyen, Steven Zhang, Hosseinali Asgharian, Martin Dodel, Juliane Winkler, Faraz K. Mardakheh, Daniel Markett, Albertas Navickas, Lisa Fish, Bruce Culbertson
Cancer cells often co-opt post-transcriptional regulatory mechanisms to achieve pathologic expression of gene networks that drive metastasis. Translational control is a major regulatory hub in oncogenesis, however its effects on cancer progression re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48536ebba8b49f8b57135497019f00dc
https://doi.org/10.1101/2021.10.04.463118
https://doi.org/10.1101/2021.10.04.463118
Autor:
Caroline C. Escoubas, Leah C. Dorman, Phi T. Nguyen, Christian Lagares-Linares, Haruna Nakajo, Sarah R. Anderson, Beatriz Cuevas, Ilia D. Vainchtein, Nicholas J. Silva, Yinghong Xiao, Peter V. Lidsky, Ellen Y. Wang, Sunrae E. Taloma, Hiromi Nakao-Inoue, Bjoern Schwer, Raul Andino, Tomasz J. Nowakowski, Anna V. Molofsky
SummaryMicroglia are brain resident phagocytes that can engulf synaptic components and extracellular matrix as well as whole neurons. However, whether there are unique molecular mechanisms that regulate these distinct phagocytic states is unknown. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32d4dfab35cc3d1bbd40ad782fcefd82
https://doi.org/10.1101/2021.04.29.441889
https://doi.org/10.1101/2021.04.29.441889
Akademický článek
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Autor:
Mazen A. Kheirbek, Jerika J. Barron, Leah C. Dorman, Phi T. Nguyen, Ilia D. Vainchtein, Rafael T. Han, Hiromi Nakao-Inoue, Ari B. Molofsky, Simon Pan, Anna V. Molofsky, Sunrae E. Taloma
Publikováno v:
Cell
Cell, vol 182, iss 2
Cell, vol 182, iss 2
Synapse remodeling is essential to encode experiences into neuronal circuits. Here, we define a molecular interaction between neurons and microglia that drives experience-dependent synapse remodeling in the hippocampus. We find that the cytokine inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7e9287e241721fc0543de43e166c1c
https://europepmc.org/articles/PMC7497728/
https://europepmc.org/articles/PMC7497728/
Autor:
Jessica Sullivan, Oliver Hofmann, Scott B. Ficarro, John N. Hutchinson, Jarrod A. Marto, Roland Csépányi-Kömi, Erzsébet Ligeti, Phi T. Nguyen, Éva Wisniewski, Amy J. Wagers, Leo D. Wang
Publikováno v:
Blood. 128:1465-1474
Protein phosphorylation is a central mechanism of signal transduction that both positively and negatively regulates protein function. Large-scale studies of the dynamic phosphorylation states of cell signaling systems have been applied extensively in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66bbc794aa8df09dfefee696a11447b
https://doi.org/10.1182/blood-2016-05-711424
https://doi.org/10.1182/blood-2016-05-711424
Autor:
R. Grant Rowe, Amy J. Wagers, Samantha J. Ross, Leo D. Wang, George Q. Daley, Silvia Coma, Ronald Mathieu, Phi T. Nguyen, Patricia Sousa, Areum Han, Antony Rodriguez, Daniel S. Pearson
Publikováno v:
The Journal of Experimental Medicine
Daley and collaborators show that endogenous Lin28b drives erythroid-dominant fetal hematopoiesis and that decreases in Lin28b activate adult granulocyte-predominant hematopoiesis.
For appropriate development, tissue and organ system morphogenes
For appropriate development, tissue and organ system morphogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3935fb87bb27725e4d7b52391e7a7a9d
https://doi.org/10.1084/jem.20151912
https://doi.org/10.1084/jem.20151912
Autor:
John G. Miller, Elliott C. Chien, Omar Akil, Leah C. Dorman, Shane A. Liddelow, Anna V. Molofsky, Phi T. Nguyen, Ilia D. Vainchtein, Kevin W. Kelley, Ben A. Barres, Satoru Joshita, Jeanne T. Paz, Frances S. Cho, Gregory Chin, Hiromi Nakao-Inoue, Ari B. Molofsky
Publikováno v:
Science (New York, N.Y.). 359(6381)
Call to action The developing brain initially makes more synapses than it needs. With further development, excess synapses are pruned away, leaving mature circuits. Synapses can be eliminated by microglia, which engulf and destroy them. Vainchtein et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260c92bda52ed55acc074228e6e8e9e6
https://pubmed.ncbi.nlm.nih.gov/29563573
https://pubmed.ncbi.nlm.nih.gov/29563573