Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Phenylalanine analog"'
Autor:
Byungseop Yang, Inchan Kwon
Publikováno v:
Molecular Pharmaceutics. 18:2397-2405
Human serum albumin (HSA) has been used to extend the serum half-life of therapeutic proteins owing to its exceptionally long serum half-life via the neonatal Fc receptor (FcRn)-mediated recycling mechanism. In most cases, only one HSA molecule was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b8d2b01d9fed3d830b55ba8ef1e6a7
https://doi.org/10.1021/acs.molpharmaceut.1c00231
https://doi.org/10.1021/acs.molpharmaceut.1c00231
Publikováno v:
New Journal of Chemistry. 43:12396-12409
Supramolecular hydrogels obtained from fluorenylmethoxycarbonyl (Fmoc)-functionalized phenylalanine and short peptides containing phenylalanine find potential applications in the biomedical field. Although the significance of the phenyl moiety in hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096499064ada1a2e146b2bbc95bb2bee
https://doi.org/10.1039/c9nj01781j
https://doi.org/10.1039/c9nj01781j
Publikováno v:
Organic and Biomolecular Chemistry, Vol. 17, No 28 (2019) pp. 6905-6910
The stereoselective synthesis of chiral macrocycles bearing two aliphatic amide functional groups is reported. After the amidation mediated by TBD, a guanidine derivative, the olefin transposition step is performed with a slight excess of t-BuOK. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1c42e1340c5f080526feda4361dca8
https://archive-ouverte.unige.ch/unige:120385
https://archive-ouverte.unige.ch/unige:120385
Autor:
Joanna Olechowicz, Katarzyna Ciacka, Olga Andrzejczak, Agnieszka Gniazdowska, Paweł Staszek, Renata Bogatek, Kim H. Hebelstrup, Urszula Krasuska
Publikováno v:
Andrzejczak, O, Krasuska, U, Olechowicz, J, Staszek, P, Ciacka, K, Bogatek, R, Hebelstrup, K & Gniazdowska, A 2018, ' Destabilization of ROS metabolism in tomato roots as a phytotoxic effect of meta-tyrosine ', Plant Physiology and Biochemistry, vol. 123, pp. 369-377 . https://doi.org/10.1016/j.plaphy.2017.12.024
meta -Tyrosine ( m -Tyr) is a non-protein amino acid produced in both plants and animals. Primary mode of action of this phenylalanine analog is its incorporation into protein structure leading to formation of aberrant molecules. An increased level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e753b168ef193479c8e5646a7747b8
https://pubmed.ncbi.nlm.nih.gov/29304482
https://pubmed.ncbi.nlm.nih.gov/29304482
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-13 (2017)
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-13 (2017)
Background Lactic acid bacteria (LAB) are receiving more attention to act as cell factories for the production of high-value metabolites. However, the molecular tools for genetic modifying these strains are mainly vector-based double-crossover strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c8d43cc4ef78db85de3a5f862bb52b
https://doi.org/10.1186/s12934-017-0731-8
https://doi.org/10.1186/s12934-017-0731-8
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
Studies of the dental caries pathogen Streptococcus mutans have benefitted tremendously from its sophisticated genetic system. As part of our own efforts to further improve upon the S. mutans genetic toolbox, we previously reported the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750c4d57c07e9fe0bc6c43824d984277
http://journal.frontiersin.org/article/10.3389/fcimb.2017.00202/full
http://journal.frontiersin.org/article/10.3389/fcimb.2017.00202/full
Publikováno v:
Enzyme and Microbial Technology. :44-47
2-Phenylethanol (2-PE) is an aromatic alcohol with a rose scent, which is used in the cosmetics, fragrance and food industries. 2-PE is produced in a few yeast strains by Ehrlich pathway. In this study, Kluyveromyces marxianus was genetically enginee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872010598bf4b9d303fd938d7096b0fa
https://doi.org/10.1016/j.enzmictec.2014.04.011
https://doi.org/10.1016/j.enzmictec.2014.04.011
New ACE Inhibitor Designed from Nicotianamine and Its Docking Pose Prediction Using the Gold Program
Publikováno v:
Journal of Drug Design and Medicinal Chemistry. 5:33
Hypertension is currently one of the most serious health issues worldwide. Nicotianamine, a non-peptide-type amino acid trimer, is ubiquitously present in higher plants and plays a role as an internal metal transporter. It is known that nicotianamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::817f8dd8d9c985a8725ca26b82991411
https://doi.org/10.11648/j.jddmc.20190503.11
https://doi.org/10.11648/j.jddmc.20190503.11
Publikováno v:
Rapid Communications in Mass Spectrometry. 27:835-841
RATIONALE Melphalan is a widely used cytotoxic agent in cancer treatments. This phenylalanine analog has been shown an effective drug in the treatment of breast cancer, multiple myeloma and melanoma of the extremities. A good knowledge of the drug's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fc89fb27fba305fca9cffb6df6da289
https://doi.org/10.1002/rcm.6515
https://doi.org/10.1002/rcm.6515
Autor:
Inchan Kwon, Eun Sil Choi
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152826 (2016)
PLoS ONE
PLoS ONE
Multiple-site-specific incorporation of a noncanonical amino acid into a recombinant protein would be a very useful technique to generate multiple chemical handles for bioconjugation and multivalent binding sites for the enhanced interaction. Previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7736dddecf8e4fafd2456094f9798912
http://europepmc.org/articles/PMC4814082?pdf=render
http://europepmc.org/articles/PMC4814082?pdf=render