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pro vyhledávání: '"Phenoxybenzamine Hydrochloride"'
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Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 191:113618
The current United States Pharmacopeia–National Formulary (USP–NF) and the British Pharmacopoeia phenoxybenzamine (PBA) hydrochloride drug substance and drug product monographs describe an HPLC procedure for the determination of a specified impur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad803006024c5a6014967ab1458ceaa
https://doi.org/10.1016/j.jpba.2020.113618
https://doi.org/10.1016/j.jpba.2020.113618
Autor:
Zhen-Hua Chen, Mao-Hua Ding, Weilin Jin, Yi Bao, Wei Sun, Xiaojun Wu, Zhen Cai, Hongkang Hu, Chen-ran Zhang, Xian-Bin Lin, Yi Chen, Jun Qian, Cheng-yin Lu, Guohan Hu, Lei Jiang, Jue-Yu Zhou
Publikováno v:
Tumor Biology. 37:2901-2908
Phenoxybenzamine hydrochloride (PHEN) is a selective antagonist of both α-adrenoceptor and calmodulin that exhibits anticancer properties. The aim of this study was to explore the anti-tumor function of PHEN in glioma. Cell proliferation assay was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835eb290b14943fc5e6ebf54a0db3ed4
https://doi.org/10.1007/s13277-015-4102-y
https://doi.org/10.1007/s13277-015-4102-y
Publikováno v:
Tetrahedron Letters. 56:5269-5271
A simple and efficient synthesis of chiral drugs (R)-mexiletine 1, an anti-arrhythmic drug and (R)-phenoxybenzamine hydrochloride 2, an anti-hypertensive drug has been described via controlled reductive ring opening of chiral aziridine as a key step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08d817ce33daaec0c782d0b34de0f21d
https://doi.org/10.1016/j.tetlet.2015.07.032
https://doi.org/10.1016/j.tetlet.2015.07.032
Publikováno v:
Journal of Luminescence. 137:162-167
A new, rapid and sensitive flow-injection chemiluminescence (FI-CL) method was developed and validated for the determination of two alpha (α)-adrenoreceptor blockers: phentolamine mesylate (PM) and phenoxybenzamine hydrochloride (PH). The method was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9352f68b909c019aecdec0a6b12e7d4
https://doi.org/10.1016/j.jlumin.2012.12.030
https://doi.org/10.1016/j.jlumin.2012.12.030
Publikováno v:
Tetrahedron: Asymmetry. 21:2825-2829
A practical and highly efficient enantioselective synthesis of ( R )-phenoxybenzamine hydrochloride has been described for the first time using Jacobsen’s hydrolytic kinetic resolution of a terminal epoxide as a key step and source of chirality.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e446056d97ed9f1405be0c1fea56ad
https://doi.org/10.1016/j.tetasy.2010.11.011
https://doi.org/10.1016/j.tetasy.2010.11.011
Publikováno v:
Journal of Analytical Chemistry. 64:847-852
A sequential injection analysis (SIA) system is described for the determination of phenoxybenzamine hydrochloride and metoclopramide using spectrophotometer as detector. The method is based on the detection of an unstable red intermediate compound re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cefb0f353f4b85d40f72bef52c3025
https://doi.org/10.1134/s1061934809080139
https://doi.org/10.1134/s1061934809080139
Autor:
Meltem Önder, Esra Adişen
Publikováno v:
Journal of the American Academy of Dermatology. 60:325-328
Cutaneous leiomyomas are benign neoplasms with smooth muscle differentiation. The), are painful tumors of the skin. Nearly 90% of patients report lesion-associated pain, characteristically precipitated by cold or trauma. In the published literature,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2216e3008638afb6d23d0d51bb90c96e
https://doi.org/10.1016/j.jaad.2008.05.044
https://doi.org/10.1016/j.jaad.2008.05.044
Autor:
Jan B.A. Habraken, Jan Booij, Berthe L. F. van Eck-Smit, Hein J. Verberne, Frits Moet, Jos Eersels, G. Aernout Somsen, Kora de Bruin
Publikováno v:
European journal of nuclear medicine and molecular imaging, 33(4), 483-490. Springer Verlag
PURPOSE: No-carrier-added (nca) MIBG is primarily associated with specific uptake (i.e. uptake-1 mechanism). We evaluated the hypothesis that nca MIBG will be less influenced by changes in extra-neuronal uptake (i.e. uptake-2 mechanism) compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573374f08d2a881e7dd3a8243bd3f4ff
https://doi.org/10.1007/s00259-005-0022-1
https://doi.org/10.1007/s00259-005-0022-1
Publikováno v:
University of Western Australia
The stability of phenoxybenzamine hydrochloride in various oral liquids was studied. Phenoxybenzamine hydrochloride powder or capsules were combined with various vehicles to prepare 10-mL formulations with a drug concentration of 2 mg/mL and a 20-mL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c5d83e50712616aeb4d2e5f6e684f3
https://doi.org/10.1093/ajhp/54.18.2073
https://doi.org/10.1093/ajhp/54.18.2073