Výsledky vyhledávání - "Phenotypic complexity"

Decoding 'Unnecessary Complexity': A Law of Complexity and a Concept of Hidden Variation Behind 'Missing Heritability' in Precision Medicine

Autor: Rama S. Singh

Publikováno v: Journal of Molecular Evolution

The high hopes for the Human Genome Project and personalized medicine were not met because the relationship between genotypes and phenotypes turned out to be more complex than expected. In a previous study we laid the foundation of a theory of comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4b51c4b51d45c5329f21ef5c3b16be
https://pubmed.ncbi.nlm.nih.gov/34341835

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Phenotypic Noise and the Cost of Complexity

Autor: Charles Rocabert, Carole Knibbe, Guillaume Beslon, Samuel Bernard

Publikováno v: EvoLyon 2019
EvoLyon 2019, Nov 2019, Lyon, France
Evolution-International Journal of Organic Evolution
Evolution-International Journal of Organic Evolution, 2020, ⟨10.1111/evo.14083⟩
Evolution-International Journal of Organic Evolution, Wiley, 2020, ⟨10.1111/evo.14083⟩

Experimental studies demonstrate the existence of phenotypic diversity despite constant genotype and environment. Theoretical models based on a single phenotypic character predict that during an adaptation event, phenotypic noise should be positively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decdbcbb433f5f47a273a6a54b5eea9d
https://hal.archives-ouvertes.fr/hal-02402443/file/poster2_v3.pdf

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Genomic Complexity Places Less Restrictions on the Evolution of Young Coexpression Networks than Protein–Protein Interactions

Autor: Yan-Ting Jin, Feng-Biao Guo, Ju Wang, Nini Rao, Meng-Ze Du, Wen Wei

Publikováno v: Genome Biology and Evolution

The differences in evolutionary patterns of young protein–protein interactions (PPIs) among distinct species have long been a puzzle. However, based on our genome-wide analysis of available integrated experimental data, we confirm that young genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ce980bdd0b28fff16973a314ddc1bc
https://doi.org/10.1093/gbe/evw198

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Akademický článek

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Dissertation/ Thesis

Étude de l'évolution des micro-organismes bactériens par des approches de modélisation et de simulation informatique

Autor: Rocabert, Charles

Variation et sélection sont au coeur de l'évolution Darwinienne. Cependant, ces deux mécanismes dépendent de processus eux-mêmes façonnés par l'évolution. Chez les micro-organismes, qui font face à des environnements souvent variables, ces p

Externí odkaz: http://www.theses.fr/2017LYSEI106/document

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Robustness, Evolvability and Phenotypic Complexity: Insights from Evolving Digital Circuits

Autor: Stefano Nolfi, Nicola Milano, Paolo Pagliuca

Publikováno v: Evolutionary intelligence
12 (2019): 83–95. doi:10.1007/s12065-018-00197-z
info:cnr-pdr/source/autori:Milano N.; Pagliuca P.; Nolfi S./titolo:Robustness, evolvability and phenotypic complexity: insights from evolving digital circuits/doi:10.1007%2Fs12065-018-00197-z/rivista:Evolutionary intelligence (Print)/anno:2019/pagina_da:83/pagina_a:95/intervallo_pagine:83–95/volume:12

We show how the characteristics of the evolutionary algorithm influence the evolvability of candidate solutions, i.e. the propensity of evolving individuals to generate better solutions as a result of genetic variation. More specifically, (1+{\lambda

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