Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Phenazepam"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 199-207 (2024)
Introduction. The presence of the active metabolite (3-hydroxyphenazepam, 3-OH-PHEN), the wide interindividual variability of the therapeutic effect of phenazepam (PHEN), as well as its active moiety in the blood, determine the relevance of therapeut
Externí odkaz:
https://doaj.org/article/14f29716d5054deab514808eb0b7f4c1
Publikováno v:
Arhiv za Higijenu Rada i Toksikologiju, Vol 74, Iss 4, Pp 224-231 (2023)
This review article takes a closer look at a new class of psychoactive substances called designer benzodiazepines (DBZs) and the challenges of their detection. These are adinazolam, clonazolam, deschloroetizolam, diclazepam, etizolam, flualprazolam,
Externí odkaz:
https://doaj.org/article/c2dd4da89e61499b81a3b59266f88992
Publikováno v:
Неотложная медицинская помощь, Vol 12, Iss 2, Pp 217-223 (2023)
BACKGROUND The market of hypnotic and sedative drugs is being updated due to the high toxicity of barbiturates and the limitations of their use. Currently, safer drugs such as Z-drugs, Doxylamine, and some benzodiazepine derivatives are often prescri
Externí odkaz:
https://doaj.org/article/8607265db2804cde80467a575cfd9cff
Publikováno v:
Неотложная медицинская помощь, Vol 12, Iss 1, Pp 37-44 (2023)
AIM OF THE STUDY To study benzodiazepine poisoning in geriatric patients compared to patients of working age.MATERIAL AND METHODS We examined 82 patients with benzodiazepine poisoning, hospitalized in the Department of Acute Poisoning and Somatopsych
Externí odkaz:
https://doaj.org/article/756561a7f5b640ffaf6ed002c1f70068
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 0 (2023)
Introduction. In conducting of therapeutic drug monitoring (TDM), often such situation arises where the drug concentration has measured by different methods or in different laboratories. To combine and analyze the data obtained with different methods
Externí odkaz:
https://doaj.org/article/0cbc345d4f4442b2b1d3766cc436e38c
Publikováno v:
Современная терапия психических расстройств, Vol 2020, Iss 2 (53), Pp 19-25 (2020)
В целях подтверждения биоэквивалентности новой ородиспергируемой (ОДт) лекарственной формы препарата феназепам® и его традиционной пе
Externí odkaz:
https://doaj.org/article/9e27774917994528a1d186c3477a6b38
Autor:
D. V. Ivashchenko, O. V. Tereshchenko, I. I. Temirbulatov, K. A. Akmalova, E. A. Grishina, M. S. Zastrozhin, L. M. Savchenko, E. A. Bryun, D. A. Sychev
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 12, Iss 2, Pp 17-22 (2020)
Phenazepam is a benzodiazepine tranquilizer that is widely used in Russia. The drug is metabolized by cytochrome P450 3A (CYP3A) isozymes. Since their substrates have an affinity for P-glycoprotein, the polymorphic variants in the ABCB1 gene may affe
Externí odkaz:
https://doaj.org/article/9d0c6b0bd07445248026e3297ae469d4
Autor:
Mark Makarov, Yuri I. Sysoev, Oksana Agafonova, Veronika A. Prikhodko, Eduard Korkotian, Sergey V. Okovityi
Publikováno v:
Brain Sciences, Vol 13, Iss 3, p 408 (2023)
One of the most important tasks in neuroscience is the search for theoretical foundations for the development of methods for diagnosing and treating neurological pathology, and for assessing the effect of pharmacological drugs on the nervous system.
Externí odkaz:
https://doaj.org/article/5ee9cd233a6d42d3adfa61f6e24c3daf
Publikováno v:
Неотложная медицинская помощь, Vol 7, Iss 4, Pp 319-324 (2019)
Background. The relative availability of Phenazepam makes it a frequent cause of overdose, suicide and non-medical use. At the same time, it remains insufficiently studied in chemical and toxicological terms.The aim of study. to create an accessible,
Externí odkaz:
https://doaj.org/article/cf8707382eb14fb7b8ae7f9b7969e2c4
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 8, Iss 3, Pp 158-161 (2018)
X-ray powder diffraction is one of the methods used for detection and analysis of polymorphic forms of pharmaceutical substances. The article elucidates the concept of polymorphism, briefly explains physical characteristics of this phenomenon, condit
Externí odkaz:
https://doaj.org/article/8d48a2ecd8e64c23b345d6c82948bd71