Zobrazeno 1 - 10
of 4 517
pro vyhledávání: '"Phase I study"'
Autor:
Tomohiro Yamaki, Maidinamu Yakufujiang, Nobuo Oka, Daisuke Ito, Masaru Odaki, Shigeki Kobayashi, Yoshinori Higuchi
Publikováno v:
Brain Disorders, Vol 13, Iss , Pp 100123- (2024)
Background: Despite evidence regarding the benefits of transcranial direct current stimulation (tDCS) in patients with severe traumatic brain injury, few trials have examined the treatment safety. Therefore, we created a phase I trial in Japan to inv
Externí odkaz:
https://doaj.org/article/9bf8e5f597784125b0a55fa8eeb48e0b
Autor:
Hui Jiang, Qiaoqiao Li, Baoqing Chen, Mian Xi, Kanjiebubi Makelike, Shiliang Liu, Yonghong Hu, Yujia Zhu
Publikováno v:
Cancer Medicine, Vol 12, Iss 14, Pp 15187-15198 (2023)
Abstract Background This phase I study aimed to assess the safety, dose‐limiting toxicity (DLT), maximum tolerated dose (MTD) and preliminary effect of nanoparticle albumin‐bound (nab)‐paclitaxel in combination with concurrent chemoradiotherapy
Externí odkaz:
https://doaj.org/article/4fe0fa39b65d495c92d2f8902825346e
Autor:
Dan Liu, Furong Kou, Jifang Gong, Zhiqiang Wang, Xiaotian Zhang, Jian Li, Yan Li, Jie Li, Jun Zhou, Ming Lu, Xicheng Wang, Zhihao Lu, Yanshuo Cao, Jianjun Zou, Xiaoyu Zhu, Ruihua Xu, Lin Shen
Publikováno v:
Cancer Medicine, Vol 12, Iss 9, Pp 10704-10714 (2023)
Abstract Aim Pyrotinib (an irreversible pan‐ErbB small‐molecular tyrosine kinase inhibitor) was approved in human epidermal growth factor receptor 2 (HER2)‐positive breast cancer and showed great antitumor activity in preclinical studies of gas
Externí odkaz:
https://doaj.org/article/63e320f911764ac5aff79f726b7be149
Autor:
María Victoria Mateos, Felipe Prosper, Jesús Martin Sánchez, Enrique M. Ocio, Albert Oriol, Cristina Motlló, Jean‐Marie Michot, Isidro Jarque, Rebeca Iglesias, María Solé, Sara Martínez, Carmen Kahatt, Salvador Fudio, Gema Corral, Ali Zeaiter, Lola Montilla, Vincent Ribrag
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 3999-4009 (2023)
Abstract Previous studies showed antitumor activity for plitidepsin plus dexamethasone (DXM) in relapsed/refractory multiple myeloma (r/r MM), and in vitro synergism with bortezomib (BTZ) or DXM against MM cells. This phase I trial evaluated plitidep
Externí odkaz:
https://doaj.org/article/b95587b8097742e08480c61a22a7ee24
Akademický článek
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Autor:
Raoof Mustafa, Sullivan Kevin M., Frankel Paul H., Fakih Marwan, Synold Timothy W., Lim Dean, Woo Yanghee, Paz Isaac Benjamin, Fong Yuman, Thomas Rebecca Meera, Chang Sue, Eng Melissa, Tinsley Raechelle, Whelan Richard L., Deperalta Danielle, Reymond Marc A., Jones Jeremy, Merchea Amit, Dellinger Thanh H.
Publikováno v:
Pleura and Peritoneum, Vol 7, Iss 4, Pp 169-177 (2022)
Peritoneal metastasis (PM) from appendiceal cancer or colorectal cancer (CRC) has significant morbidity and limited survival. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) is a minimally invasive approach to treat PM. We aim to conduct
Externí odkaz:
https://doaj.org/article/690153add2fe4855821424097e736092
