Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pharnuk Suthipinijtham"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 63:19-26
Irofulven (MGI 114, NSC 683863) is a semisynthetic derivative of illudin S, a natural product present in the Omphalotus illudins (Jack O'Lantern) mushroom. This novel agent produces DNA damage, that in contrast to other agents, is predominately ignor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e73e7ca3527c20a53533ac7ab98435
https://doi.org/10.1007/s00280-008-0703-0
https://doi.org/10.1007/s00280-008-0703-0
Publikováno v:
Investigational New Drugs. 26:407-415
The novel agent Irofulven (HMAF, NSC 683863) has demonstrated significant antitumor activity against solid tumors in various xenograft models and human clinical trials. The antitumor potential of combining irofulven with 72 different anti-metabolite,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f8a01ad2213a0e5dfee114a2ff9adc
https://doi.org/10.1007/s10637-008-9113-8
https://doi.org/10.1007/s10637-008-9113-8
Publikováno v:
Mammalian Genome. 12:664-667
Chromatin remodeling complexes are important factors in the regulation of RNA transcription, DNA replication, recombination, and repair. Two major types of chromatin remodeling enzymes appear to be highly conserved: the ATP-dependent remodeling compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abb25f955e4a2ec684949f39c789606
https://doi.org/10.1007/s003350020036
https://doi.org/10.1007/s003350020036
Autor:
McMorris Tc, Michael J. Kelner, Leita A. Estes, Nicole A. Trani, Rafael Rojas, Pharnuk Suthipinijtham, Tami R. Velasco
Publikováno v:
Investigational new drugs. 20(3)
The aim of this study was to determine the antitumor activity of irofulven when administered in combination with a variety of antimitotic agents. Irofulven in combination with either paclitaxel or docetaxel demonstrated synergistic activity in both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c7f8497e03e5634b9227071bbff520
https://pubmed.ncbi.nlm.nih.gov/12201490
https://pubmed.ncbi.nlm.nih.gov/12201490
Publikováno v:
Investigational New Drugs; Oct2008, Vol. 26 Issue 5, p407-415, 9p, 1 Diagram, 2 Charts, 4 Graphs