Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Pharmacomicrobiomics"'
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract In the absence of an effective vaccine or curative treatment for HIV, the global HIV/AIDS epidemic continues despite significant advances in treatment and prevention. Antiretroviral therapy (ART) drugs have transformed HIV from a terminal il
Externí odkaz:
https://doaj.org/article/5baa91bc72b14912ba70e38cd904e29e
Autor:
Maja Đanić, Nikolija Marković, Tijana Ostojić, Milena Kojić, Slavica Lazarević, Momir Mikov, Nebojša Pavlović
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Acquiring sufficient knowledge and understanding the importance of intestinal microbiota and probiotics in health and disease, as well as their potential for interactions with concurrently administered drugs, can significantly inf
Externí odkaz:
https://doaj.org/article/a5419a2363ff4e28a7bb0c7f1d16fd5d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Tylosin, an antibiotic with a long history in treating respiratory bacterial infections, has unknown effects on the gut microbiota of healthy and infected pigs. The study aimed to investigate the effect of a therapeutic dose of tylosin on sw
Externí odkaz:
https://doaj.org/article/636c2351e7d646d0a845a4d99407392f
Autor:
Maja Đanić, Nebojša Pavlović, Dragana Zaklan, Bojan Stanimirov, Slavica Lazarević, Hani Al-Salami, Momir Mikov
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundGliclazide, a second-generation sulfonylurea derivative still widely used as a second-line treatment for type 2 diabetes mellitus, is well known to be subject to interindividual differences in bioavailability, leading to variations in thera
Externí odkaz:
https://doaj.org/article/39ca9e30567c4902bffa620778be1fd3
Autor:
Janine Ziemons, Lars E. Hillege, Romy Aarnoutse, Judith de Vos-Geelen, Liselot Valkenburg-van Iersel, Jasper Mastenbroek, Robin van Geel, David J. M. Barnett, Sander S. Rensen, Ardy van Helvoort, Lotte H. J. Dopheide, Guus Roeselers, John Penders, Marjolein L. Smidt, Koen Venema
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background 5-Fluorouracil (5-FU) is used as an antineoplastic agent in distinct cancer types. Increasing evidence suggests that the gut microbiota might modulate 5-FU efficacy and toxicity, potentially affecting the patient’s prognosis. Th
Externí odkaz:
https://doaj.org/article/8c054ca32f3b4fc89ee48efa04a62aa6
Akademický článek
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Autor:
WANG Na, HAN Xiaohong
Publikováno v:
Xiehe Yixue Zazhi, Vol 14, Iss 5, Pp 932-938 (2023)
Despite the rapid development of antitumor drugs, the limited drug response rate and adverse drug reactions have severely limited their clinical application. In recent years, the concept of 'pharmacomicrobiomics' has emerged, and more and more studie
Externí odkaz:
https://doaj.org/article/5b3b60278af74ee783133d3623b62721
Autor:
Karolina Kaźmierczak-Siedlecka, Nikola Bulman, Paweł Ulasiński, Bartosz Kamil Sobocki, Karol Połom, Luigi Marano, Leszek Kalinowski, Karolina Skonieczna-Żydecka
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTIntestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotransformation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobioti
Externí odkaz:
https://doaj.org/article/fd83a32c9db747bcaebfda4f879ea61e
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTPrevotella copri is an abundant member of the human gastrointestinal microbiome, whose relative abundance has curiously been associated with positive and negative impacts on diseases, such as Parkinson’s disease and rheumatoid arthritis. Ye
Externí odkaz:
https://doaj.org/article/76a335cb768b4e46837ce7e988bda93f
Autor:
Stacyann Bailey, Keith Fraser
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The gut microbiome has been implicated in a multitude of human diseases, with emerging evidence linking its microbial diversity to osteoporosis. This review article will explore the molecular mechanisms underlying perturbations in the gut microbiome
Externí odkaz:
https://doaj.org/article/dc3e277e62eb4c2f8fe11578781d8c7f