Zobrazeno 1 - 10
of 2 171
pro vyhledávání: '"Pharmacokinetic properties"'
Autor:
Said Rammali, Abderrazak Idir, Marouane Aherkou, Alin Ciobică, Fatima Zahra Kamal, Mohamed El Aalaoui, Abdellatif Rahim, Abdelkrim khattabi, Zyad Abdelmajid, Abderrahim Aasfar, Vasile Burlui, Gabriela Calin, Ioannis Mavroudis, Bouchaib Bencharki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract This study aimed to explore the antioxidant potential of the ethyl acetate extract of Streptomyces coeruleofuscus SCJ strain, along with its inhibitory effects on the triple-negative human breast carcinoma cell line (MDA-MB-468). The ethyl a
Externí odkaz:
https://doaj.org/article/65070100696a40faa393e7550aa66617
Autor:
Yan Peng, Ying Peng, Wei Zhang, Siyi Zhang, Huiqian Peng, Zhen Li, Bo Li, Linyi Liu, Linsheng Zhuo, Zhen Wang, Junbo Wu, Weifan Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionN-phenyl-2-(aniline) analog N53 is a previously discovered dual inhibitor of Topo I and COX-2, which exhibited significant anti-colon cancer activity in vitro, but the poor solubility and moderate anti-cancer activity in vivo hindered its
Externí odkaz:
https://doaj.org/article/c904f946c6d5490a92cbc774ccf20004
Autor:
Nadia Arrousse, Elyor Berdimurodov, Mariia Bogacheva, Fathiah Zakham, Soukaina Esslali, Sghir EL Kadiri, Mustapha Taleb, Olli Vapalahti
Publikováno v:
Heliyon, Vol 10, Iss 19, Pp e38587- (2024)
The threat of emerging viral outbreaks has increased the need for fast and effective development of therapeutics against emerging pathogens. One approach is to modify the structure of existing therapeutic agents to achieve the desired antiviral prope
Externí odkaz:
https://doaj.org/article/321af51b8e5c4d7abeec4c6514dfe6d1
Autor:
R. Yuvashri, Era Dravida Thendral, D. Reuben Jonathan, A. Anish Fathima, K. Laavanya, G. Usha
Publikováno v:
Chemical Physics Impact, Vol 9, Iss , Pp 100663- (2024)
In this work, a series of curcumin derivatives have been synthesized using Claisen Schmidt condensation reaction & Schotten-Baumann reaction, and they were screened through in-silico and in-vitro analysis to determine their capacity as a potential ag
Externí odkaz:
https://doaj.org/article/204c8b2bb1914fd19bf4f49c0a7d5635
Autor:
Di Yang, Xiaoxu Cheng, Meiling Fan, Dong Xie, Zhiqiang Liu, Fei Zheng, Yulin Dai, Zifeng Pi, Hao Yue
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Wu-tou decoction (WTD), a traditional Chinese medicine prescription, is used to treat rheumatoid arthritis (RA). It works by controlling intestinal flora and its metabolites, which in turn modulates the inflammatory response and intestinal b
Externí odkaz:
https://doaj.org/article/5e7e007a2903445490f5a2da1ad081d2
Autor:
Chijing Zuo, Fulong Yan, Jie Wang, Yulong Zhu, Wenhui Luo, Yan Liu, Wanhui Liang, Weidong Yu, Jingwei Zhang, Daiyin Peng, Xiaodong Ma, Can Peng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Ischemic stroke is the second most common chronic disease worldwide and is associated with high morbidity and mortality. Thromboembolism and platelet aggregation are the most characteristic features of stroke. Other than aspirin, no sta
Externí odkaz:
https://doaj.org/article/420159efc7554f579e13e7463351d40d
Autor:
Sabrina Kelly Silva Alves, Cássio Silva Sousa, Edilanne Katrine Amparo Viana, Hellen Cris Araújo Souza, Maycon Douglas Araújo Souza, Arthur Serejo Neves Ribeiro, Vanessa de Sousa do Vale, Muhammad Torequl Islam, Joabe Lima Araújo, Jefferson Almeida Rocha
Publikováno v:
Drugs and Drug Candidates, Vol 2, Iss 4, Pp 781-795 (2023)
SARS-CoV-2 (severe acute respiratory distress syndrome coronavirus 2) is the causative agent for the novel coronavirus disease 2019 (COVID-19). It raises serious biosecurity questions due to its high contagious potential, thereby triggering rapid and
Externí odkaz:
https://doaj.org/article/2a8d4779056c4c8eb0a66cb5d8039a3b
Autor:
Akhileshwar Kumar Srivastava, Divya Singh, Priya Yadav, Monika Singh, Sandeep Kumar Singh, Ajay Kumar
Publikováno v:
Stresses, Vol 3, Iss 3, Pp 615-628 (2023)
To cure SARS-CoV-2 infection, the repurposing of conventional antiviral drugs is currently advocated by researchers, though their action is not very effective. The present study, based on in silico methods, was intended to increase the therapeutic po
Externí odkaz:
https://doaj.org/article/a27c8e65c9644a429081957db18c9f9b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.