Zobrazeno 1 - 10
of 1 818
pro vyhledávání: '"Pharmacokinetic interaction"'
Autor:
Serena Di Cosimo, José Manuel Pérez-García, Meritxell Bellet, Florence Dalenc, Miguel J. Gil Gil, Manuel Ruiz-Borrego, Joaquín Gavilá, Elena Aguirre, Peter Schmid, Frederik Marmé, Joseph Gligorov, Andreas Schneeweiss, Joan Albanell, Pilar Zamora, Duncan Wheatley, Eduardo Martínez de Dueñas, Kepa Amillano, Eileen Shimizu, Miguel Sampayo-Cordero, Javier Cortés, Antonio Llombart-Cussac
Publikováno v:
Breast, Vol 76, Iss , Pp 103761- (2024)
Background: The capsule formulation of CDK4/6 inhibitor palbociclib has reduced solubility at gastric pH > 4.5 and may have decreased activity when used with proton-pump inhibitors (PPI). Herein, we report the effect of PPI on palbociclib capsule act
Externí odkaz:
https://doaj.org/article/d3b96315025744e9a531e42906d8d57a
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 4, Pp 661-666 (2023)
Both curcumin and naproxen possess the activity of pain relief, which makes it possible to co-administrate these drugs in the same prescription. This study aimed to assess the potential pharmacokinetic interaction of naproxen with curcumin in rats. S
Externí odkaz:
https://doaj.org/article/a549fa428dd4421086563311e5c5c59c
Autor:
Mei Zhang, Ze-En Li, Ming-Hui Duan, Yan Dai, Yang-Guang Jin, Yue Liu, Yan-Ni Zhang, Xing-Ping Li, Fan Yang
Publikováno v:
Poultry Science, Vol 103, Iss 2, Pp 103373- (2024)
ABSTRACT: This study investigates the combined effects of chitooligosaccharide (COS) and florfenicol (FLO) on the inhibition of Escherichia coli in vitro, as well as the pharmacokinetic interactions between these compounds in healthy chickens. The mi
Externí odkaz:
https://doaj.org/article/aed8746990f74fa1b10a06a89f984ae2
Autor:
Huitao Gao, Hongzhong Liu, Xin Zheng, Xinge Cui, Stephanie Bricout-Hennel, Arnaud Lucien, Pauline Lauruol, Yaqin Wang, Xue Wang, Hongyun Wang, Chen Rui
Publikováno v:
Acta Materia Medica, Vol 2, Iss 1, Pp 84-95 (2023)
S05590 is a fixed-dose combination of perindopril tert-butylamine 4 mg/indapamide 1.25 mg, and S06593 is a fixed-dose combination of perindopril arginine 5 mg/indapamide 1.25 mg/amlodipine 5 mg. The purpose of this study was to determine whether phar
Externí odkaz:
https://doaj.org/article/bbb1e308c7e64178b0ef8316785c484b
Autor:
Taísa Busaranho Franchin, Jonata Augusto de Oliveira, Caroline Damico Candido, Evelin dos Santos Martins, Elias Carvalho Padilha, Michel Leandro de Campos, Rosângela Gonçalves Peccinini
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2023)
Abstract Tuberculosis treatment consists of a drug combination, where isoniazid is the core drug and alcoholism is a factor highly related to poor patient compliance with the therapy. CYP2E1 is an enzyme involved both in the metabolism of ethanol and
Externí odkaz:
https://doaj.org/article/20097610c5e04839bb9bda02a24498f4
Publikováno v:
Poultry Science, Vol 102, Iss 1, Pp 102225- (2023)
ABSTRACT: The study aimed to investigate the possible role of efflux transporter proteins in the pharmacokinetics of enrofloxacin (ENR) in broilers in the model of co-administration of activated charcoal (AC) or cyclosporine A (CsA). The concentratio
Externí odkaz:
https://doaj.org/article/4758c66d6b1f4326820e658b79da82e8
Akademický článek
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Publikováno v:
Metabolites, Vol 13, Iss 8, p 897 (2023)
Because of the high research and development cost of new drugs, the long development process of new drugs, and the high failure rate at later stages, combining past drugs has gradually become a more economical and attractive alternative. However, the
Externí odkaz:
https://doaj.org/article/2c4395a9fe9d4f78b8e72e2c188335a9
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 30-39 (2021)
Combined oral contraception and treatment of new coronavirus infection (COVID-19): issues of drug interaction This article examines the interaction of combined oral contraceptives with drugs recommended in the treatment of new coronavirus infection (
Externí odkaz:
https://doaj.org/article/df49f69474054052b3bc80ac010395ea
Autor:
Jannarin Nontakham, Pongpun Siripong, Hitoshi Sato, Savita Chewchinda, Kuntarat Arunrungvichian, Jantana Yahuafai, Arman Syah Goli, Vilasinee Hirunpanich Sato
Publikováno v:
Heliyon, Vol 8, Iss 6, Pp e09764- (2022)
Context: Direct evidence of Triphala-drug interactions has not been provided to date. Objective: This study was aimed to determine the effects of Triphala on cytochrome P450 (CYP) isoforms and P-glycoprotein (P-gp) in vitro, and to investigate pharma
Externí odkaz:
https://doaj.org/article/9bb006d6b8d842ba8b03970d137999b9