Výsledky vyhledávání - "Pham-Huu Chanh"

Aminopyridazine derivatives and TXA2-PGI2 balance

Autor: Catherine Rubat, Coudert P, R. Kaiser, B. Lasserre, J. Couquelet, Pham Huu Chanh

Publikováno v: Prostaglandins, Leukotrienes and Essential Fatty Acids. 40:143-148

Experiments carried out under the conditions adopted showed the strong affinity of aminopyridazine derivatives for the eicosanoids TXA2 and PGI2. But this affinity depended on the chemical structure of the molecule: a small change in the radical graf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa05a7c5792bf7cce8ee567c0a66af2
https://doi.org/10.1016/0952-3278(90)90157-g

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Insulin and Glucagon Impairments in Relation with Islet Cells Morphological Modifications Following Long Term Pancreatic Duct Ligation in the Rabbit – A Model of Non-insulin-dependent Diabete

Autor: B. Lasserre, M. Daumas, A. Pham Huu Chanh, J. Catala, E. Hollande

Publikováno v: International journal of experimental diabetes research

Plasma levels of glucose, insulin and glucagon were measured at various time intervals after pancreatic duct ligation (PDL) in rabbits. Two hyperglycemic periods were observed: one between 15–90 days (peak at 30 days of 15.1 ± 1.2mmol/l, p < 0.01)

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Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit

Autor: A. Pham Huu Chanh, C. Navarro-Delmasure, J. Catala, E. Hollande, B. Lasserre

Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids. 62(5)

Having developed a non-insulin-dependent diabetes mellitus (NIDDM) syndrome model in the rabbit using Wirsung duct ligation, it appeared interesting to use it to study the relationship between glycemia and the plasma levels of TXA(2)and PGI(2), and o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fee21b0d48e65d82af7a04e37a0909
https://pubmed.ncbi.nlm.nih.gov/10883059

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Thromboxane A2 biosynthesis inhibitors: synthesis and evaluation of pyrazolotriazinyl alkanoic acids

Autor: J. Couquelet, C. Navarro-Delmasure, A. Pham Huu Chanh, B. Lasserre, S. Mavel, V. Dossou-Gbete, Coudert P

Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids. 51(3)

A novel series of (6-aryl-4-oxo-pyrazolo 2,3-d] [1,2,5] triazin-3-yl) alkanoic acids was synthesized and evaluated in vitro as thromboxane A 2 (TXA 2 ) biosynthesis inhibitors. The experiments were carried out using arachidonic acid (32.8 μM) as a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b006734c15a2c24bdf29a46402f7b36
https://pubmed.ncbi.nlm.nih.gov/7824529

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Myocardial prostacyclin and thromboxane A2 synthetase activities during ischemia and reperfusion in isolated rabbit heart

Autor: B. Lasserre, V. Dossou-Gbete, A. Pham Huu Chanh, Ramez Chahine

Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids. 43(4)

The aim of the study was to determine the prostacyclin (PGI2) and thromboxane A2 (TXA2) synthetase activities of myocardial tissue and their variation during ischemia and reperfusion. Regional ischemia was induced by 10 min occlusion of the left ante

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb72899ef8b363b40d05c2bf00f355
https://pubmed.ncbi.nlm.nih.gov/1946554

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Comparative effects of some 3-amino 4,6-diarylpyridazines on the biosynthesis in vitro of TXA2 and PGI2- and on the TXA2- and PGI2-synthesizing activities of cardiac tissue

Autor: B. Lasserre, V. Dossou-Gbete, Catherine Rubat, Pham Huu Chanh, R. Kaiser, J. Couquelet, Ramez Chahine, Coudert P

Publikováno v: Prostaglandins, leukotrienes, and essential fatty acids. 39(1)

Some 3-amino 4,6-diarylpyridazine derivatives were tested for their effects on TXA2 and PGI2 biosyntheses in vitro and on the TXA2- and PGI2-synthesizing activities of cardiac tissue. Horse platelet and aorta microsomes were used as sources of thromb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e08f3b7cd7f0a240fe7737c35f63b
https://pubmed.ncbi.nlm.nih.gov/2111026

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The cardiac release of prostacyclin, throm☐ane A2 and anti throm☐ane synthetase factor during the cold ischemic cardiac arrest

Autor: Y. Glock, A. Pham Huu Chanh, C. Navarro-Delmazure, B. Lasserre, Pham Huu Chanh

Publikováno v: Journal of Molecular and Cellular Cardiology. 22:S26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1988a9e093b1b06a6479143804c0f58
https://doi.org/10.1016/0022-2828(90)92022-7

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Taurine and icosanoids in the heart

Autor: A. Pham Huu Chanh, V. Dossou-Gbete, C. Navarro-Delmasure, Pham Huu Chanh, Ramez Chahine

Publikováno v: Prostaglandins, Leukotrienes and Medicine. 28:243-254

Experiments were carried out on non-working isolated rabbit hearts perfused by Tyrode solution: the effects of Taurine introduced into the coronary circulation were studied on the biosynthesis of the anti-thromboxane synthetase factor ("FATS") and on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b594fe9deb584c7c862a2a1a3cb5ba5f
https://doi.org/10.1016/0262-1746(87)90114-4

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