Výsledky vyhledávání

Dissertation/ Thesis

Network-based methods to identify mechanisms of action in disease and drug perturbation profiles using high-throughput genomic data

Autor: Pham, Lisa M.

In the past decade it has become increasingly clear that a biological response is rarely caused by a single gene or protein. Rather, it is a result of a myriad of biological factors, constituting a systematic network of biological variables that span

Externí odkaz: https://hdl.handle.net/2144/49042

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Report

Perturbation Detection Through Modeling of Gene Expression on a Latent Biological Pathway Network: A Bayesian hierarchical approach

Autor: Pham, Lisa M., Carvalho, Luis, Schaus, Scott, Kolaczyk, Eric D.

Cellular response to a perturbation is the result of a dynamic system of biological variables linked in a complex network. A major challenge in drug and disease studies is identifying the key factors of a biological network that are essential in dete

Externí odkaz: http://arxiv.org/abs/1409.0503

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The Virtually Cyclic Classifying Space of the Heisenberg Group

Autor: Manion, Andrew, Pham, Lisa, Poelhuis, Jonathan

We are interested in the relationship between the virtual cohomological dimension (or vcd) of a discrete group Gamma and the smallest possible dimension of a model for the classifying space of Gamma relative to its family of virtually cyclic subgroup

Externí odkaz: http://arxiv.org/abs/0812.2192

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