Zobrazeno 1 - 10
of 495
pro vyhledávání: '"Phalguni Gupta"'
Autor:
Jan Kristoff, Mariana L. Palma, Tatiana M. Garcia-Bates, Chengli Shen, Nicolas Sluis-Cremer, Phalguni Gupta, Charles R. Rinaldo, Robbie B. Mailliard
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 295-306 (2019)
Background: Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4+ T cells within those who are infected. Finding a safe and effective means to induce latency reversal
Externí odkaz:
https://doaj.org/article/bf3cb0e7aa5a452fabd01ba01eb02660
Publikováno v:
Bio-Protocol, Vol 9, Iss 10 (2019)
The latent HIV-1 viral reservoir in resting CD4+ (rCD4+) T cells represents a major barrier to an HIV-1 cure. There is an ongoing effort to identify therapeutic approaches that will eliminate or reduce the size of this reservoir. However, clinical in
Externí odkaz:
https://doaj.org/article/8e553b8fec6d493f9e8eb64f92864a80
Publikováno v:
Al Ameen Journal of Medical Sciences, Vol 08, Iss 01, Pp 45-49 (2015)
Objectives: Radiotherapy is an integral part of Cancer management. The unavailability of adequate number of teletherapy machines in developing countries like India has compounded upon the increasing incidence of Cancer, leading to a huge deficit betw
Externí odkaz:
https://doaj.org/article/dc3110d8fe8c4f0282543263febfd8f8
Autor:
Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, Charles R. Rinaldo
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
Externí odkaz:
https://doaj.org/article/129f6269170b45fa8e4f31ad97e64932
Autor:
Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, Charles R. Rinaldo
Publikováno v:
mBio, Vol 7, Iss 3 (2016)
ABSTRACT Curing HIV-1 infection will require elimination of persistent cellular reservoirs that harbor latent virus in the face of combination antiretroviral therapy (cART). Proposed immunotherapeutic strategies to cure HIV-1 infection include enhanc
Externí odkaz:
https://doaj.org/article/8cdc6aa18bb14393afbdb23f988cb829
Autor:
Giovanna Rappocciolo, Mariel Jais, Paolo Piazza, Todd A. Reinhart, Stella J. Berendam, Laura Garcia-Exposito, Phalguni Gupta, Charles R. Rinaldo
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT HIV-1-infected nonprogressors (NP) inhibit disease progression for years without antiretroviral therapy. Defining the mechanisms for this resistance to disease progression could be important in determining strategies for controlling HIV-1 in
Externí odkaz:
https://doaj.org/article/81e4fa9071a544f0b23ab381825ea254
Autor:
Matthew P Wood, Amy L Cole, Piotr Ruchala, Alan J Waring, Lisa C Rohan, Preston Marx, Patrick M Tarwater, Phalguni Gupta, Alexander M Cole
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55478 (2013)
Fusion inhibitors are a class of antiretroviral drugs used to prevent entry of HIV into host cells. Many of the fusion inhibitors being developed, including the drug enfuvirtide, are peptides designed to competitively inhibit the viral fusion protein
Externí odkaz:
https://doaj.org/article/184cd43f85334e159d10842125ac60d7
Autor:
Colleen R Eade, Camila Diaz, Matthew P Wood, Kathryn Anastos, Bruce K Patterson, Phalguni Gupta, Amy L Cole, Alexander M Cole
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50106 (2012)
Bacterial vaginosis (BV) is the most commonly treated female reproductive tract affliction, characterized by the displacement of healthy lactobacilli by an overgrowth of pathogenic bacteria. BV can contribute to pathogenic inflammation, preterm birth
Externí odkaz:
https://doaj.org/article/ecfa43b76bda4296bb6bfe2cae14b69d
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32539 (2012)
Although there are different strains of HIV-1 in a chronically infected individual, only one or limited virus strains are successfully transmitted to a new individual. The reason for this "transmission bottleneck" is as yet unknown.A human cervical e
Externí odkaz:
https://doaj.org/article/d467656964bc4d9d9875673d89cd3e1c
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25956 (2011)
To investigate the geographical origin and evolution dynamics of HIV-1 subtype C infection in India.Ninety HIV-1 subtype C env gp120 subtype C sequences from India were compared with 312 env gp120 reference subtype C sequences from 27 different count
Externí odkaz:
https://doaj.org/article/29b095fbd0504d2382f99a103a3d01df