Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Phalguni A. Alladi"'
Autor:
S. N. Suresh, Aravinda K. Chavalmane, Malini Pillai, Veena Ammanathan, D. J. Vidyadhara, Haorei Yarreiphang, Shashank Rai, Abhik Paul, James P. Clement, Phalguni A. Alladi, Ravi Manjithaya
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Mechanistic insights into aggrephagy, a selective basal autophagy process to clear misfolded protein aggregates, are lacking. Here, we report and describe the role of Estrogen Related Receptor α (ERRα, HUGO Gene Nomenclature ESRRA), new molecular p
Externí odkaz:
https://doaj.org/article/7773f462a4df4bb7a7da10d3bab13297
Autor:
Anu Mary Varghese, Mausam Ghosh, Savita Kumari Bhagat, K. Vijayalakshmi, Veeramani Preethish-Kumar, Seena Vengalil, Pradeep-Chandra-Reddy Chevula, Saraswati Nashi, Kiran Polavarapu, Meenakshi Sharma, Rupinder Singh Dhaliwal, Mariamma Philip, Atchayaram Nalini, Phalguni Anand Alladi, Talakad N. Sathyaprabha, Trichur R. Raju
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Cerebrospinal fluid from amyotrophic lateral sclerosis patients (ALS-CSF) induces neurodegenerative changes in motor neurons and gliosis in sporadic ALS models. Search for identification of toxic factor(s) in CSF revealed an enhan
Externí odkaz:
https://doaj.org/article/56747c5928d646cd97f314edd90ee00d
Autor:
Suresh SN, Janhavi Pandurangi, Ravi Murumalla, Vidyadhara DJ, Lakshmi Garimella, Achyuth Acharya, Shashank Rai, Abhik Paul, Haorei Yarreiphang, Malini S Pillai, Mridhula Giridharan, James P Clement, Phalguni Anand Alladi, Taslimarif Saiyed, Ravi Manjithaya
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 260-273 (2019)
Background: Plethora of efforts fails to yield a single drug to reverse the pathogenesis of Parkinson's disease (PD) and related α-synucleopathies. Methods: Using chemical biology, we identified a small molecule inhibitor of c-abl kinase, PD180970 t
Externí odkaz:
https://doaj.org/article/5fa4a5ea36dd41c3a5a47d5140b05e73
Autor:
Pooja-Shree Mishra, K. Vijayalakshmi, A. Nalini, T. N. Sathyaprabha, B. W. Kramer, Phalguni Anand Alladi, T. R. Raju
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-18 (2017)
Abstract Background Microglial cell-associated neuroinflammation is considered as a potential contributor to the pathophysiology of sporadic amyotrophic lateral sclerosis. However, the specific role of microglia in the disease pathogenesis remains to
Externí odkaz:
https://doaj.org/article/429f7de2858c495c99dce2a7a3cc8d70
Autor:
H. J. Jyothi, Bidisha Bhaduri, Maithily Hingmire, Priyansha Verma, T. C. Yasha, Phalguni Anand Alladi
Publikováno v:
Healthy Ageing and Longevity ISBN: 9783031224676
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63c25e28b6da39fabfbf90b872d5dab6
https://doi.org/10.1007/978-3-031-22468-3_12
https://doi.org/10.1007/978-3-031-22468-3_12
Autor:
Shruthi Shanmukha, Gayathri Narayanappa, Atchayaram Nalini, Phalguni Anand Alladi, Trichur R. Raju
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 4 (2018)
Skeletal muscle atrophy is the most prominent feature of amyotrophic lateral sclerosis (ALS), an adult-onset neurodegenerative disease of motor neurons. However, the contribution of skeletal muscle to disease progression remains elusive. Our previous
Externí odkaz:
https://doaj.org/article/0a94cb27e1f041d3b8a27103426d125b
Publikováno v:
Neurotoxicity Research. 39:1892-1907
Parkinson disease (PD) prevalence varies by ethnicity. In an earlier study, we replicated the reduced vulnerability to PD in an admixed population, using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-susceptible C57BL/6 J, MPTP-resistant CD-1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd237d86092b88f63ea981a4b2317b7c
https://doi.org/10.1007/s12640-021-00439-6
https://doi.org/10.1007/s12640-021-00439-6
Autor:
Haorei Yarreiphang, D J Vidyadhara, Anand Krishnan Nambisan, Trichur R Raju, BK Chandrashekar Sagar, Phalguni Anand Alladi
Identification of genetic mutations in Parkinson’s disease (PD) promulgates the genetic nature of disease susceptibility. Resilience-associated genes being unknown till date, the normal genetic makeup of an individual may be determinative too. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a391cf9d0e29ae860554a054865069
https://doi.org/10.1101/2022.10.05.511004
https://doi.org/10.1101/2022.10.05.511004
Autor:
Aditi Naskar, Albert Stezin, Arpitha Dharmappa, Shantala Hegde, Mariamma Philip, Nitish Kamble, Jitender Saini, K. Sandhya, Utpal Tatu, Ravi Yadav, Pramod Kumar Pal, Phalguni Anand Alladi
Publikováno v:
ACS chemical neuroscience. 13(7)
Parkinson's disease (PD) with cognitive impairment (PDCI) is essentially diagnosed through clinical and neuropsychological examinations. There is a need to identify biomarkers to foresee cognitive decline in them. We performed label-free unbiased non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::972479e6e25bb25c150f51d7e517c65a
https://pubmed.ncbi.nlm.nih.gov/35200010
https://pubmed.ncbi.nlm.nih.gov/35200010
Autor:
Bidisha Bhaduri, Phalguni Anand Alladi
Publikováno v:
The Biology of Glial Cells: Recent Advances ISBN: 9789811683121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48912f9cc69216dce6eba2b914cf373d
https://doi.org/10.1007/978-981-16-8313-8_15
https://doi.org/10.1007/978-981-16-8313-8_15