Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Phaik-Leng Cheah"'
Publikováno v:
PeerJ, Vol 12, p e17643 (2024)
Background Alzheimer’s disease (AD) is the most common type of dementia that affects the elderly population. Lately, blood-based proteomics have been intensively sought in the discovery of AD biomarkers studies due to the capability to link externa
Externí odkaz:
https://doaj.org/article/726f7e9b4fdc46ce8c9593ee617fc7d0
Publikováno v:
Applied Sciences, Vol 13, Iss 5, p 3071 (2023)
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive and functional impairment. Recent research has focused on the deregulation of microRNAs (miRNAs) in blood as the potential biomarkers for AD. As such, a differential
Externí odkaz:
https://doaj.org/article/5d9dc309e0f149678ad091c85928aaeb
Autor:
Lee Fah Yap, Sook Ling Lai, Anthony Rhodes, Hans Prakash Sathasivam, Maizaton Atmadini Abdullah, Kin-Choo Pua, Pathmanathan Rajadurai, Phaik-Leng Cheah, Selvam Thavaraj, Max Robinson, Ian C. Paterson
Publikováno v:
Infectious Agents and Cancer, Vol 13, Iss 1, Pp 1-6 (2018)
Abstract Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising in Western countries and this has been attributed to human papillomavirus (HPV) infection. p16 expression is a marker for HPV infection and p16 positiv
Externí odkaz:
https://doaj.org/article/b51939456b914631a3b3ca6ea7ff626d
Publikováno v:
PeerJ, Vol 6, p e5530 (2018)
Background Except for a few studies with contradictory observations, information is lacking on the possibility of association between DNA mismatch repair (MMR) status and the presence of cancer stem cells in colorectal carcinoma (CRC), two important
Externí odkaz:
https://doaj.org/article/4ae7e4ed33d54f0ba35418f2d3b08485
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161720 (2016)
Telomeres shorten with physiological aging but undergo substantial restoration during cancer immortalization. Increasingly, cancer studies utilize the archive of formalin-fixed, paraffin-embedded (FFPE) tissues in diagnostic pathology departments. Co
Externí odkaz:
https://doaj.org/article/cb8610ede7c94bdfa2d3bbad2246db08
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168238 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0161720.].
Externí odkaz:
https://doaj.org/article/14302db0b0b043e78ec24ad62cd61f7b
Autor:
Shamsul Mohd Zain, Rosmawati Mohamed, David N Cooper, Rozaimi Razali, Sanjay Rampal, Sanjiv Mahadeva, Wah-Kheong Chan, Arif Anwar, Nurul Shielawati Mohamed Rosli, Anis Shafina Mahfudz, Phaik-Leng Cheah, Roma Choudhury Basu, Zahurin Mohamed
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95604 (2014)
Between 10 and 25% of individuals with non-alcoholic fatty liver disease (NAFLD) develop hepatic fibrosis leading to cirrhosis and hepatocellular carcinoma (HCC). To investigate the molecular basis of disease progression, we performed a genome-wide a
Externí odkaz:
https://doaj.org/article/a543aa02099c4469afb9733498d5a2f0
Autor:
Shamsul Mohd Zain, Zahurin Mohamed, Sanjiv Mahadeva, Sanjay Rampal, Roma Choudhury Basu, Phaik-Leng Cheah, Agus Salim, Rosmawati Mohamed
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58538 (2013)
Angiotensin II type 1 receptor (AGTR1) has been reported to play a fibrogenic role in non-alcoholic fatty liver disease (NAFLD). In this study, five variants of the AGTR1 gene (rs3772622, rs3772627, rs3772630, rs3772633, and rs2276736) were examined
Externí odkaz:
https://doaj.org/article/5705524e1d0a457b8ba17ef2edad06db
Publikováno v:
Malaysian Journal of Pathology; Dec2023, Vol. 45 Issue 3, p473-478, 6p
Autor:
Phaik-Leng Cheah, Chee Shee Chai, Diana Bee-Lan Ong, Chong-Kin Liam, Gwo Fuang Ho, Mau Ern Poh, Adlinda Alip, Yong Kek Pang
Publikováno v:
Cancer Management and Research. 12:5439-5450
Background This study aims to determine the predictors of acquired exon 20 T790M mutation in advanced non-small cell lung cancer (NSCLC) patients harbouring sensitizing epidermal growth factor receptor (EGFR) mutation following the failure of first-